ChemicalBook > CAS DataBase List > 6-Chloropyridazin-3-amine

6-Chloropyridazin-3-amine

Product Name
6-Chloropyridazin-3-amine
CAS No.
5469-69-2
Chemical Name
6-Chloropyridazin-3-amine
Synonyms
3-AMINO-6-CHLOROPYRIDAZINE;6-AMino-3-chloropyridazine;6-Chloropyridazin-3-amine, 3-Amino-6-chloro-1,2-diazine;3-Amino-6-chL;oropyridazine;BUTTPARK 44\01-57;TIMTEC-BB SBB005487;Risdiplam Impurity 7;Chloridazon Impurity 4;6-chloro-3-pyridazinamin
CBNumber
CB3189300
Molecular Formula
C4H4ClN3
Formula Weight
129.55
MOL File
5469-69-2.mol
More
Less

6-Chloropyridazin-3-amine Property

Melting point:
210 °C
Boiling point:
363.2±22.0 °C(Predicted)
Density 
1.437±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
4.06±0.10(Predicted)
color 
Light Brown to Brown
BRN 
110918
InChI
InChI=1S/C4H4ClN3/c5-3-1-2-4(6)8-7-3/h1-2H,(H2,6,8)
InChIKey
DTXVKPOKPFWSFF-UHFFFAOYSA-N
SMILES
C1(N)=NN=C(Cl)C=C1
CAS DataBase Reference
5469-69-2(CAS DataBase Reference)
EPA Substance Registry System
3-Pyridazinamine, 6-chloro- (5469-69-2)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22-22
Safety Statements 
26-36/37/39-22-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
A1817
Product name
3-Amino-6-chloropyridazine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$60
Updated
2025/07/31
TCI Chemical
Product number
A1817
Product name
3-Amino-6-chloropyridazine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$174
Updated
2025/07/31
TRC
Product number
A603511
Product name
3-Amino-6-chloropyridazine
Packaging
100g
Price
$965
Updated
2021/12/16
TRC
Product number
A603511
Product name
3-Amino-6-chloropyridazine
Packaging
5g
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
069641
Product name
3-Amino-6-chloropyridazine
Purity
98%
Packaging
25g
Price
$66
Updated
2021/12/16
More
Less

6-Chloropyridazin-3-amine Chemical Properties,Usage,Production

Chemical Properties

Brown Solid

Uses

3-Amino-6-chloropyridazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Definition

ChEBI: 3(S)-hydroxy-13-cis-eicosenoyl-CoA is a member of pyridazines.

Synthesis

141-30-0

5469-69-2

The general procedure for the synthesis of 3-amino-6-chloropyridazine from 3,6-dichloropyridazine was as follows: 3,6-dichloropyridazine (107,500 mg, 3.36 mmol) was slowly added to 2.0 M ammonia methanol solution (NH3 in MeOH, 17 mL, 33.6 mmol). The reaction mixture was heated at 130 °C for 96 h and subsequently cooled to room temperature. After the reaction was completed, water was carefully added. The organic compounds were extracted with ethyl acetate and the combined organic phases were washed with saturated aqueous sodium chloride solution. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by column chromatography to afford the target compound 3-amino-6-chloropyridazine (108d, 265 mg, 61% yield) as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CD3OD) δ 6.95 (d, J = 9.6 Hz, 1H), 7.34 (d, J = 9.2 Hz, 1H) and 13C NMR (100 MHz, CD3OD) δ 119.8, 131.1, 147.1, 161.5.

References

[1] Patent: WO2013/59587, 2013, A1. Location in patent: Page/Page column 74; 75
[2] Patent: EP2768509, 2017, B1. Location in patent: Paragraph 0237; 0238
[3] Journal of Heterocyclic Chemistry, 2013, vol. 50, # 5, p. 1165 - 1173
[4] Organic and Biomolecular Chemistry, 2010, vol. 8, # 18, p. 4131 - 4136
[5] Patent: WO2007/26623, 2007, A1. Location in patent: Page/Page column 6-7

6-Chloropyridazin-3-amine Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Ethanol 3,6-Dichloropyridazine

Preparation Products

More
Less

6-Chloropyridazin-3-amine Suppliers

Americas 1 Belgium 2 Canada 1 China 386 Europe 1 France 1 Germany 7 India 17 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 18 United States 40 Global 477
shanghai huiyu
Tel
15380804498
Email
330062898@qq.com
Country
China
ProdList
241
Advantage
58
Chemtour Biotech Co., Ltd
Tel
+8617327281506
Email
market@chemtour.com
Country
China
ProdList
1521
Advantage
58
Nanjing Puxin Pharmaceutical Technology Co., Ltd
Tel
17366295326
Fax
QQ360829978
Email
puxinpharma_2017@126.com
Country
China
ProdList
2444
Advantage
58
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
993
Advantage
62
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12000
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16077
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6945
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
skychemical Co.Ltd
Tel
021-20958197 20965099
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
1183
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1931
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Changzhou Wanyao Biotechnology Co., Ltd.
Tel
0519-89185693 15312551983
Fax
0519-89185693
Email
2410037592@qq.com
Country
China
ProdList
261
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
3997
Advantage
55
Wuhan Haizheng Industry & Trade Development Co. Ltd
Tel
027-8866 0053/88660577/88660578
Fax
027-8899 1911
Country
China
ProdList
1073
Advantage
55
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098, 021-37212705 021-37212706, 13391256916
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
570
Advantage
55
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Ascepion Pharmaceuticals, Inc.
Tel
+86-512-86881668
Fax
+86-512-62956001
Country
China
ProdList
100
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
More
Less

View Lastest Price from 6-Chloropyridazin-3-amine manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-Amino-6-chloropyridazine 5469-69-2
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-02
Dideu Industries Group Limited
Product
6-Chloropyridazin-3-amine 5469-69-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-01
Zhuozhou Wenxi import and Export Co., Ltd
Product
6-Chloropyridazin-3-amine 5469-69-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11

5469-69-2, 6-Chloropyridazin-3-amineRelated Search:

Hydrochlorothiazide Bis(2-ethylhexyl)amine Pyridazin-3-amine ALTRENOGEST Relugolix Impurity 1 Relugolix Impurity 10 Chemtrue-RL-N5 Relugolix Impurity 2 Triallylamine 3-Aminophenol Glycine Dibenzylamine 6-Aminocaproic acid Sulfachloropyridazine sodium Hydralazine Thioridazine Tris(hydroxymethyl)aminomethane 2-((2,6-difluorobenzyl)(ethoxycarbonyl)amino)-4-((dimethylamino)methyl)-5-(4-nitrophenyl)thiophene-3-carboxylic acid

  • BUTTPARK 44\01-57
  • AMINO(3-)-6-CHLOROPYRIDAZINE
  • 6-CHLOROPYRIDAZIN-3-AMINE
  • 6-CHLORO-3-PYRIDAZINYLAMINE
  • 6-CHLOROPYRIDAZIN-3-YLAMINE
  • 6-Chloropyridazin-3-amine, 3-Amino-6-chloro-1,2-diazine
  • 3-AMino-6-chloropyridazine CAS 5469-69-2
  • 6-Chloropyridazinyl-3-amine
  • Pyridazine, 3-amino-6-chloro-
  • Pyridazine, 3-amino-6-chloro- (8CI)
  • 6-Chloropyridazin-3-amine(96%)
  • 3-Pyridazinamine, 6-chloro-
  • 3-Amino-6-chL
  • oropyridazine
  • 3-AMINO-6-CHLOROPYRIDAZINE
  • TIMTEC-BB SBB005487
  • 6-chloro-3-pyridazinamin
  • 3-AMINO-6-CHLOROPYRIDAZINE,6-CHLOROPYRIDAZIN-3-AMINE
  • 6-Chloro-3-aminopyridazine
  • 3-Amino-6-chloropyrazine
  • 3-AMINO-6-CHLOROPYRIDAZINE 98%
  • 6-Chloropyridazin-3-amine ,98%
  • 6-Chloro-3-pyridazinamine
  • 3-AMINO-6-CHLOROPYDIRAZINE
  • 3-Amino-6-chloropyradazine
  • 3-Amino-6-chloropyridazine ,98%
  • 6-AMino-3-chloropyridazine
  • 6-chloropyridazin-3-amine(SALTDATA: FREE)
  • 3-Amino-6-chloropyridazine &gt
  • 6-Chloropyridazin-3-amine ISO 9001：2015 REACH
  • 3-Amino-6-chloro pyridizine
  • Chloridazon Impurity 4
  • Risdiplam Impurity 7
  • 5469-69-2
  • 5496-69-2
  • 5496-69-9
  • amine| alkyl chloride
  • Chemical Amines
  • Pyrazines, Pyrimidines & Pyridazines
  • Pyridazine series
  • Amines
  • Pyrazines, Pyrimidines & Pyridazines
  • API intermediates
  • pyridazine
  • Building Blocks
  • blocks
  • Heterocycles
  • Amines and Anilines
  • Risdiplam