ChemicalBook > CAS DataBase List > (S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane

(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane

Product Name
(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
CAS No.
60456-22-6
Chemical Name
(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
Synonyms
(S)-(-)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE;(S)-(-)-4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE;)-2,2-dimethyL;S-Chloropropanediol acetonide;(S)-3-Chloro-1,2-propandiol acetonide;(S)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE;(S)-(-)-3-Chloro-1,2-propandiol acetonoide;S-4-chloromethyl-2,2-dimethyl-1,3-dioxoane;(S)-2,2-Dimethyl-4-Chlormethyl-1,3-Dioxolane;(S)-2,2-Dimethyl-4-Chloromethyl-1,3-Dioxolane
CBNumber
CB3197501
Molecular Formula
C6H11ClO2
Formula Weight
150.6
MOL File
60456-22-6.mol
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(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane Property

Boiling point:
63 °C37 mm Hg(lit.)
alpha 
-42 º (neat 24 ºC)
Density 
1.103 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.434(lit.)
Flash point:
123 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
soluble in Chloroform, Ethyl Acetate
form 
clear liquid
color 
Colorless to Almost colorless
Specific Gravity
1.103
BRN 
7409638
InChI
InChI=1S/C6H11ClO2/c1-6(2)8-4-5(3-7)9-6/h5H,3-4H2,1-2H3/t5-/m1/s1
InChIKey
BNPOTXLWPZOESZ-RXMQYKEDSA-N
SMILES
O1C[C@@H](CCl)OC1(C)C
CAS DataBase Reference
60456-22-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
10-41-36/37/38-25
Safety Statements 
16-26-36-45-37/39-36/39
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
JH6950000
HazardClass 
3
PackingGroup 
III
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H301Toxic if swalloed

H318Causes serious eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
456144
Product name
(S)-(?)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane
Purity
98%
Packaging
5g
Price
$37.5
Updated
2025/07/31
Sigma-Aldrich
Product number
456144
Product name
(S)-(?)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane
Purity
98%
Packaging
1g
Price
$23
Updated
2023/06/20
TCI Chemical
Product number
C1796
Product name
(S)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
Purity
>97.0%(GC)(T)
Packaging
1g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
C1796
Product name
(S)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$77
Updated
2025/07/31
TRC
Product number
C369395
Product name
(S)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane
Packaging
50g
Price
$755
Updated
2021/12/16
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(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane Chemical Properties,Usage,Production

Description

(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is a colorless transparent liquid at room temperature and pressure. It is sensitive to acidic substances and is prone to decomposition reactions when encountering acidic substances. The chlorine atoms in its structure can undergo nucleophilic substitution reactions under the attack of organic amines and phenolic substances. This compound is an impurity of landiolol and is used for new drug research and experimental use.

Chemical Properties

(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is clear colorless to yellow liquid

Uses

(S)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane is often used in biosynthetic preparations.

Uses

(S)-(?)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane can be used as a building block in the synthesis of hydroxylated polyamine analogs of biological importance.

(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane Suppliers

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View Lastest Price from (S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane； Landiolol impurity53 60456-22-6
Price
US $0.00-0.00/BOX
Min. Order
1BOX
Purity
99%
Supply Ability
1KG 100KG 1MT
Release date
2025-04-28
Hebei Chuanghai Biotechnology Co., Ltd
Product
(S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane 60456-22-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-18
Shaanxi Dideu New Materials Co. Ltd
Product
(S)-(-)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane 60456-22-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2024-11-08

60456-22-6, (S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolaneRelated Search:

DIMETHYLTHEXYLSILYL CHLORIDE Dimethyl sulfide ETHANE Dimethyl ether Chlorodimethylphenylsilane 1,3-Dioxolane Dimethyl sebacate Dimethyl sulfoxide Dimethyl sulfate Dimethyl carbonate N,N-Dimethylformamide Poly(dimethylsiloxane) tert-Butyldimethylsilyl chloride Dimethyl fumarate CHLORODIMETHYLVINYLSILANE N,N-Dimethylacetamide (S)-(+)-3-Chloro-1,2-propanediol (R)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE

  • 1,3-DIOXOLANE, 4-(CHLOROMETHYL)-2,2-DIMETHYL-, (4S)-
  • (S)-(-)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane 98%
  • (S)-(-)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE
  • (S)-3-CHLORO-1,2-PROPANEDIOL ACETONIDE
  • (S)-(-)-4-(CHLOROMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
  • (S)-(+)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
  • (S)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE
  • S-Chloropropanediol acetonide
  • (S)-2,2-Dimethyl-4-Chloromethyl-1,3-Dioxolane
  • 1,3-Dioxolane,4-(chloromethyl)-2,2-dimethyl-,(4S)-(9CI)
  • (S)-(-)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane, 98%, ee 98%
  • (S)-(-)-4-CHLOROMETHYL-2,2-DIMETHYL-1,3-DIOXOLANE , EE 98%
  • (S)-(-)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane,98%
  • (S)-(-)-3-Chloro-1,2-propandiol acetonoide
  • S-4-chloromethyl-2,2-dimethyl-1,3-dioxoane
  • (S)-2,2-Dimethyl-4-Chlormethyl-1,3-Dioxolane
  • (S)-(-)-4-(ChloroMethyl)-2,2-diMethyl-1,3-dioxolane, 98% 5GR
  • (S)-3-Chloro-1,2-propandiol acetonide
  • (S)-4-Chloromethyl-2,2-dimethyl-1,3-dioxolane &gt
  • )-2,2-dimethyL
  • (<i>S</i>)-(?)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane
  • 60456-22-6
  • HALOGEN
  • Glycidyl Compounds, etc. (Chiral)
  • Chiral Building Blocks
  • Dioxolanes
  • Dioxanes & Dioxolanes
  • Organic Building Blocks
  • Protected Alcohols
  • Asymmetric Synthesis
  • HALOMETYL
  • API intermediates
  • Chiral Building Blocks
  • Dioxanes & Dioxolanes
  • Dioxolanes
  • Glycidyl Compounds, etc. (Chiral)
  • Synthetic Organic Chemistry
  • Chiral Building Blocks
  • Organic Building Blocks
  • Protected Alcohols