3,5-Dimethyl-4-nitro-1H-pyrazole

Product Name: 3,5-Dimethyl-4-nitro-1H-pyrazole
CAS No.: 14531-55-6
Chemical Name: 3,5-Dimethyl-4-nitro-1H-pyrazole
Synonyms: AKOS 90439;AKOS B001468;ART-CHEM-BB B001468;TIMTEC-BB SBB009217;3,5-DiMethyl-4-nitro;3,5-Dimethyl-4-nitropyrazole>3,5-DIMETHYL-4-NITRO-1H-PYRAZOLE;4-NITRO-3,5-DIMETHYL-1H-PYRAZOLE;1H-Pyrazole, 3,5-dimethyl-4-nitro-;1H-Pyrazole,3,5-dimethyl-4-nitro-(9CI)
CBNumber: CB3198467
Molecular Formula: C5H7N3O2
Formula Weight: 141.13
MOL File: 14531-55-6.mol

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3,5-Dimethyl-4-nitro-1H-pyrazole Property

Melting point:: 125.0 to 129.0 °C
Boiling point:: 325°C(lit.)
Density: 1.339±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 10.75±0.50(Predicted)
color: White to Almost white
λmax: 274nm(CHCl3)(lit.)
InChI: InChI=1S/C5H7N3O2/c1-3-5(8(9)10)4(2)7-6-3/h1-2H3,(H,6,7)
InChIKey: OFQCJVVJRNPSET-UHFFFAOYSA-N
SMILES: N1C(C)=C([N+]([O-])=O)C(C)=N1
CAS DataBase Reference: 14531-55-6(CAS DataBase Reference)

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Safety

RTECS: UQ6585000
HazardClass: IRRITANT
HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D4425
Product name: 3,5-Dimethyl-4-nitropyrazole
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $40
Updated: 2025/07/31

TCI Chemical

Product number: D4425
Product name: 3,5-Dimethyl-4-nitropyrazole
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $194
Updated: 2025/07/31

TRC

Product number: D480550
Product name: 3,5-Dimethyl-4-nitro-1H-pyrazole
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Chem-Impex

Product number: 43650
Product name: 3,5-Dimethyl-4-nitropyrazole,≥98%(GC)
Purity: ≥98%(GC)
Packaging: 5G
Price: $48.54
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD40735
Product name: 3,5-Dimethyl-4-nitRopyRazole
Packaging: 10g
Price: $107
Updated: 2021/12/16

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3,5-Dimethyl-4-nitro-1H-pyrazole Chemical Properties,Usage,Production

Uses

As Pyrazoles compound, 3,5-Dimethyl-4-nitro-1H-pyrazole has the key structures in numerous compounds of therapeutic importance. Compounds containing this ring system are known to display diverse pharmacological activities, for example as antimalarial agents , anti-inflammatory agents, and against cardiovascular disease.^[1]

Synthesis

2033-45-6

14531-55-6

General procedure for the synthesis of 3,5-dimethyl-4-nitropyrazole from 3,5-dimethyl-4-iodopyrazole: 1. 3,5-dimethyl-4-iodopyrazole (1 mmol) was dissolved in tetrahydrofuran (THF, 10 mL). 2. Add Fuajasite catalyst (250 mg) to the above solution. 3. Concentrated nitric acid (density 1.52 g/cm3, 10 mL) was added slowly. 4. Stir the reaction mixture at room temperature until the reaction is complete. 5. 5. Upon completion of the reaction, the catalyst was filtered to recover the catalyst. 6. 6. The filtrate was extracted several times with dichloromethane. 7. 7. The organic phases were combined and concentrated in vacuum to remove the solvent to give 3,5-dimethyl-4-nitropyrazole.

References

[1] Edward R T Tiekink, James L Wardell, Solange M S V Wardell. “3,5-Dimethyl-1-(4-nitro-phen-yl)-1H-pyrazole.” Acta crystallographica. Section E, Structure reports online 68 Pt 4 (2012): o1018.

3,5-Dimethyl-4-nitro-1H-pyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Dimethyl-4-nitro-1H-pyrazole Suppliers

Americas 1 China 116 Europe 2 Germany 2 India 2 Japan 1 Russia 2 The Netherlands 1 Ukraine 1 United Kingdom 6 United States 13 Global 147

Pure Chemistry Scientific Inc.

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TimTec Corporation

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View Lastest Price from 3,5-Dimethyl-4-nitro-1H-pyrazole manufacturers

Honest Joy Holdings Limited

Product: 3,5-Dimethyl-4-nitro-1H-pyrazole 14531-55-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.1%
Supply Ability: 100 tons
Release date: 2022-01-26

Career Henan Chemical Co

Product: 3,5-Dimethyl-4-nitro-1H-pyrazole 14531-55-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 500kg/month
Release date: 2019-08-01

14531-55-6, 3,5-Dimethyl-4-nitro-1H-pyrazoleRelated Search:

Dacthal 3,5-Dimethylpyrazole Dimethyl carbonate N,N-Dimethylformamide Dimethyl sulfoxide Pyraclostrobin Dimethyl ether Pyrazole Dimethyl fumarate ETHANE Dimethyl sulfate Dimethyl disulfide Zolpidem tartrate Zolpidem 2,5-dimethyl-4-nitro-2H-pyrazole-3- 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE 4-Nitropyrazole 1-ACETYL-3(5)-(HEPTAFLUORO-1-PROPYL)-5(3)-METHYL-4-(NITRO)PYRAZOLE

ART-CHEM-BB B001468

AKOS 90439

AKOS B001468

4-NITRO-3,5-DIMETHYL-1H-PYRAZOLE

3,5-DIMETHYL-4-NITRO-1H-PYRAZOLE

TIMTEC-BB SBB009217

5-23-05-00160 (Beilstein Handbook Reference)

1H-Pyrazole,3,5-dimethyl-4-nitro-(9CI)

3,5-dimethyl-4-nitro-1H-pyrazole(SALTDATA: FREE)

3,5-DiMethyl-4-nitro

3,5-Dimethyl-4-nitropyrazole&gt

1H-Pyrazole, 3,5-dimethyl-4-nitro-

14531-55-6

NITRO