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enniatin A1

Product Name
enniatin A1
CAS No.
4530-21-6
Chemical Name
enniatin A1
Synonyms
enniatin A1;2-(N-Methyl-L-valine)enniatin A;(3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
CBNumber
CB32079106
Molecular Formula
C35H61N3O9
Formula Weight
667.879
MOL File
4530-21-6.mol
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enniatin A1 Property

Melting point:
116-117 °C
Boiling point:
840.5±65.0 °C(Predicted)
Density 
1.027±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble10mg/mL
form 
White to off-white crystalline solid.
pka
-1.44±0.70(Predicted)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
45
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1(a)
PackingGroup 
I
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E5161
Product name
Enniatin A1
Purity
from Gnomonia errabunda, ≥95% (HPLC)
Packaging
1mg
Price
$211
Updated
2024/03/01
Cayman Chemical
Product number
17457
Product name
Enniatin A1
Purity
≥99%
Packaging
1mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
17457
Product name
Enniatin A1
Purity
≥99%
Packaging
5mg
Price
$698
Updated
2024/03/01
TRC
Product number
E555995
Product name
Enniatin A1
Packaging
1mg
Price
$175
Updated
2021/12/16
Usbiological
Product number
E3222-27
Product name
Enniatin A1
Packaging
1mg
Price
$426
Updated
2021/12/16
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enniatin A1 Chemical Properties,Usage,Production

Uses

Enniatins are a family of depsipeptide ionophores, produced several Fusarium species. More recently, the effects of the ennitins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex and has previously not been available for investigation.

Uses

Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex .

Uses

Enniatin A1 is a mycotoxin capable of creating negative CNS effects due to their ability to cross the blod-brain barrier. Secondary metabolite of microbes, it is associated with mold, moisture damage and asthma development.

Definition

ChEBI: An enniatin obtained from formal cyclocondensation of one N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-valine and two N-[(2R)-2-hydroxy-3-methylbu anoyl]-N-methyl-L-isoleucine units.

Biochem/physiol Actions

Enniatins are a group of cyclohexadepsipeptide mycotoxins produced by Gnomonia errabuda and several Fusaria species, with phytotoxic, antibiotic, and insecticidal activities. Enniatins function as ionophors by their incorporation into the cellular membrane to form dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. It has been demonstrated that enniatins have a cytotoxic effect on human cancer cells. Furthermore, incubation of H4IIE hepatoma cells with enniatins strongly diminished phosphorylation of the ERK (p44/p42).

enniatin A1 Preparation Products And Raw materials

Raw materials

Preparation Products

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enniatin A1 Suppliers

Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
11438
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Qingdao IniKem BioPharmaTech Co.,Ltd
Tel
0532-58268780
Fax
-
Email
sales@inikem.com
Country
China
ProdList
294
Advantage
55
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9952
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
3004654993@qq.com
Country
China
ProdList
8861
Advantage
60
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View Lastest Price from enniatin A1 manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
enniatin A1 4530-21-6
Price
US $25.00-11.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2024-08-12

4530-21-6, enniatin A1Related Search:


  • Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
  • enniatin A1
  • 2-(N-Methyl-L-valine)enniatin A
  • (3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone
  • 4530-21-6
  • C35H61N3O9