enniatin A1

Product Name: enniatin A1
CAS No.: 4530-21-6
Chemical Name: enniatin A1
Synonyms: enniatin A1;2-(N-Methyl-L-valine)enniatin A;(3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone;Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]
CBNumber: CB32079106
Molecular Formula: C35H61N3O9
Formula Weight: 667.879
MOL File: 4530-21-6.mol

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enniatin A1 Property

Melting point:: 116-117 °C
Boiling point:: 840.5±65.0 °C(Predicted)
Density: 1.027±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: soluble10mg/mL
form: White to off-white crystalline solid.
pka: -1.44±0.70(Predicted)

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Safety

Hazard Codes: T
Risk Statements: 23/24/25
Safety Statements: 45
RIDADR: 2811
WGK Germany: 3
HazardClass: 6.1(a)
PackingGroup: I

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E5161
Product name: Enniatin A1
Purity: from Gnomonia errabunda, ≥95% (HPLC)
Packaging: 1mg
Price: $211
Updated: 2024/03/01

Cayman Chemical

Product number: 17457
Product name: Enniatin A1
Purity: ≥99%
Packaging: 1mg
Price: $166
Updated: 2024/03/01

Cayman Chemical

Product number: 17457
Product name: Enniatin A1
Purity: ≥99%
Packaging: 5mg
Price: $698
Updated: 2024/03/01

TRC

Product number: E555995
Product name: Enniatin A1
Packaging: 1mg
Price: $175
Updated: 2021/12/16

Usbiological

Product number: E3222-27
Product name: Enniatin A1
Packaging: 1mg
Price: $426
Updated: 2021/12/16

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enniatin A1 Chemical Properties,Usage,Production

Uses

Enniatins are a family of depsipeptide ionophores, produced several Fusarium species. More recently, the effects of the ennitins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumour action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex and has previously not been available for investigation.

Uses

Enniatins are a family of depsipeptide ionophores produced by several Fusarium species. Recently, the effects of the enniatins on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A1 is one of four major analogues of the enniatin complex .

Uses

Enniatin A1 is a mycotoxin capable of creating negative CNS effects due to their ability to cross the blod-brain barrier. Secondary metabolite of microbes, it is associated with mold, moisture damage and asthma development.

Definition

ChEBI: An enniatin obtained from formal cyclocondensation of one N-[(2R)-2-hydroxy-3-methylbutanoyl]-N-methyl-L-valine and two N-[(2R)-2-hydroxy-3-methylbu anoyl]-N-methyl-L-isoleucine units.

Biochem/physiol Actions

Enniatins are a group of cyclohexadepsipeptide mycotoxins produced by Gnomonia errabuda and several Fusaria species, with phytotoxic, antibiotic, and insecticidal activities. Enniatins function as ionophors by their incorporation into the cellular membrane to form dimeric structures that transport monovalent ions across the membrane (especially the mitochondrial membranes) affecting oxidative phosphorylation uncoupling. It has been demonstrated that enniatins have a cytotoxic effect on human cancer cells. Furthermore, incubation of H4IIE hepatoma cells with enniatins strongly diminished phosphorylation of the ERK (p44/p42).

enniatin A1 Preparation Products And Raw materials

Raw materials

Preparation Products

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enniatin A1 Suppliers

China 53 India 1 United Kingdom 1 United States 8 Global 63

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View Lastest Price from enniatin A1 manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: enniatin A1 4530-21-6
Price: US $25.00-11.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-12

4530-21-6, enniatin A1Related Search:

GRAMICIDIN A BEAUVERICIN ENNIATIN B enniatin B1 enniatin A

Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-valyl]

enniatin A1

2-(N-Methyl-L-valine)enniatin A

(3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

4530-21-6

C35H61N3O9