Methyl 3-amino-4-chlorobenzoate
- Product Name
- Methyl 3-amino-4-chlorobenzoate
- CAS No.
- 40872-87-5
- Chemical Name
- Methyl 3-amino-4-chlorobenzoate
- Synonyms
- Intedanib Impurity 5;Methyl 3-Amino-4-chlorobenzene;METHYL 3-AMINO-4-CHLOROBENZOATE;METHYL, 4-CHLORO-3-AMINOBENZOATE;Methyl3-Amino-4-chlorobenzoate>3-amino-4-chloro-2-methylbenzoate;Amino chlorobenzoic acid methyl ester;3-AMINO-4-CHLOROBENZOIC ACID METHYL ESTER;Methyl 3-AMino-4-chlorobenzoate, 98.0%(GC&T;Benzoic acid, 3-aMino-4-chloro-, Methyl ester
- CBNumber
- CB3211933
- Molecular Formula
- C8H8ClNO2
- Formula Weight
- 185.61
- MOL File
- 40872-87-5.mol
Methyl 3-amino-4-chlorobenzoate Property
- Melting point:
- 83 °C
- Boiling point:
- 292.1±20.0 °C(Predicted)
- Density
- 1.311±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- crystalline powder
- pka
- 1.51±0.10(Predicted)
- color
- Pale lemon/gold
- CAS DataBase Reference
- 40872-87-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M1778
- Product name
- Methyl 3-Amino-4-chlorobenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $54
- Updated
- 2024/03/01
- Product number
- M1778
- Product name
- Methyl 3-Amino-4-chlorobenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $181
- Updated
- 2024/03/01
- Product number
- M328668
- Product name
- Methyl 3-Amino-4-chlorobenzoate
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- OR2041
- Product name
- Methyl 3-Amino-4-chlorobenzoate
- Packaging
- 25g
- Price
- $58
- Updated
- 2021/12/16
- Product number
- 4658-5-X6
- Product name
- Methyl 3-amino-4-chlorobenzoate
- Packaging
- 25g
- Price
- $64
- Updated
- 2021/12/16
Methyl 3-amino-4-chlorobenzoate Chemical Properties,Usage,Production
Synthesis
To a solution of 3-amino-4-chlorobenzoic acid (15.0 g, 88.0 mmol) in methanol (90.0 mL), thionyl chloride (13.0 mL) was added drop-wise at 0 °C. The resulting mixture was refluxed for 12h. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The residue was diluted with water (150 mL) and extracted with ethyl acetate. The organic layer was washed with sodium bicarbonate (50 mL) and brine solution (50 mL) and dried over sodium sulfate. The organic layer was removed under a rotary evaporator to yield Methyl 3-amino-4-chlorobenzoate (15.0 g, 92.5 per cent) as an off-white solid. 1H NMR (400 MHz, CDC13) δ 3.88 (s, 3H), 4.26 (brs, 2H), 7.29 (d, J = 8.2 Hz, 1H), 7.34-7.37 (dd, J = 1.9, 8.2 Hz, 1H), 7.45 (d, J = 1.9 Hz, 1H).
Methyl 3-amino-4-chlorobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 3-amino-4-chlorobenzoate Suppliers
- Tel
- --
- Fax
- --
- y.barysheva@ukrorgsynth.com
- Country
- Ukraine
- ProdList
- 6230
- Advantage
- 38
- Tel
- --
- Fax
- --
- enamine@enamine.net
- Country
- Ukraine
- ProdList
- 6216
- Advantage
- 67
View Lastest Price from Methyl 3-amino-4-chlorobenzoate manufacturers
- Product
- methyl 3-amino-4-chlorobenzoate 40872-87-5
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-25