ChemicalBook > CAS DataBase List > 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol

4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol

Product Name: 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol
CAS No.: 40951-69-7
Chemical Name: 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol
Synonyms: Taxiresinol;4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol;1,2-Benzenediol, 4-[(2S,3R,4R)-tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)-2-furanyl]-
CBNumber: CB32277524
Molecular Formula: C19H22O6
Formula Weight: 346.37
MOL File: 40951-69-7.mol

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4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Property

Melting point:: 157-158 °C(Solv: methanol (67-56-1))
Boiling point:: 590.3±50.0 °C(Predicted)
Density: 1.331±0.06 g/cm3(Predicted)
pka: 9.60±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0013730
Product name: (+)-TAXIRESINOL
Purity: 95.00%
Packaging: 5MG
Price: $501.31
Updated: 2021/12/16

Arctom

Product number: CFN97744
Product name: Taxiresinol
Packaging: 5mg
Price: $463
Updated: 2021/12/16

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4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Chemical Properties,Usage,Production

Uses

Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity[1].

in vivo

Taxiresinol (100 mg/kg, oral administration, once) shows significant antinociceptive activity against p-benzoquinone-induced abdominal contractions in mice^[1].

Animal Model:	Male Swiss albino mice (20-25 g)^[1]
Dosage:	100 mg/kg
Administration:	Oral administration, sixty minutes after the oral administration of test sample, the mice were intraperitoneally injected with 0.1 ml/10 g body weight of 2.5% (v/v) p-benzoquinone solution in distilled H2O.
Result:	Showed significant antinociceptive activity against p-benzoquinone-induced abdominal contractions (writhing movements) in mice, with a inhibitory ratio of 37.8%.

References

[1] Küpeli E, et al. Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L. J Ethnopharmacol. 2003 Dec;89(2-3):265-70. DOI:10.1071/bi9760365

4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol Suppliers

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40951-69-7, 4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediolRelated Search:

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4-[Tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-hydroxymethylfuran-2-yl]-1,2-benzenediol

Taxiresinol

1,2-Benzenediol, 4-[(2S,3R,4R)-tetrahydro-4-[(4-hydroxy-3-methoxyphenyl)methyl]-3-(hydroxymethyl)-2-furanyl]-

40951-69-7