ChemicalBook > CAS DataBase List > Tropisetron

Tropisetron

Product Name
Tropisetron
CAS No.
89565-68-4
Chemical Name
Tropisetron
Synonyms
CS-348;icf205-930;TROPICACID;TROPISETRON;β-Tropisetron;SS-TROPISETRON;BETA-TROPISETRON;Tropisetron USP/EP/BP;Tropisetron (ICS 205930);TROPISHTRON HYDROCHLORIDE
CBNumber
CB3236404
Molecular Formula
C17H20N2O2
Formula Weight
284.35
MOL File
89565-68-4.mol
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Tropisetron Property

Melting point:
201-202 °C
Boiling point:
448.5±35.0 °C(Predicted)
Density 
1.26
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: soluble
form 
solid
pka
15.38±0.30(Predicted)
color 
white
CAS DataBase Reference
89565-68-4(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-1146
Product name
Tropisetron
Purity
>98.0%
Packaging
10mg
Price
$79
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005560
Product name
TROPISETRON
Purity
95.00%
Packaging
10MG
Price
$203.7
Updated
2021/12/16
ChemScene
Product number
CS-1146
Product name
Tropisetron
Purity
>98.0%
Packaging
50mg
Price
$317
Updated
2021/12/16
AK Scientific
Product number
H833
Product name
beta-Tropisetron
Packaging
50mg
Price
$458
Updated
2021/12/16
ChemScene
Product number
CS-1146
Product name
Tropisetron
Purity
>98.0%
Packaging
100mg
Price
$554
Updated
2021/12/16
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Tropisetron Chemical Properties,Usage,Production

Description

Tropisetron is the third selective 5HT3-antagonist, after ondansetron and granisetron, to be introduced for the management of nausea and vomiting induced by cancer chemotherapy. Similar to the other two 5HT3-antagonists, vopisetron is superior to metoclopramide. The compound has also been reported to have antiarrhythmic activity.

Chemical Properties

Crystallized, melting point 201-202°C (dichloromethane-ethyl acetate). Tropisetron Monohydroehloride: C17H20N2O2-HCl. [105826-92-4]. Melting point 283-285°C (decomposition).

Originator

Sandoz (Switzerland)

Uses

A substance that is used to prevent nausea and vomiting caused by chemotherapy.

Definition

ChEBI: An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.

brand name

Novaban

Hazard

Human systemic effects.

Tropisetron Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tropisetron manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tropisetron 89565-68-4
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kg
Release date
2021-10-22
Shaanxi Dideu Medichem Co. Ltd
Product
Tropisetron 89565-68-4
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-05-06
Hebei Zhanyao Biotechnology Co. Ltd
Product
Tropisetron 89565-68-4
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-22

89565-68-4, TropisetronRelated Search:


  • TROPISETRON
  • 1H-Indole-3-carboxylic acid (1β,5β)-8-methyl-8-azabicyclo[3.2.1]octan-3α-yl ester
  • 1H-Indole-3-carboxylic acid, endo-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
  • Tropisetron (ICS 205930)
  • 8-methyl-8-azabicyclo(3.2.1)oct-3-ylester,endo-1h-indole-3-carboxylicaci
  • icf205-930
  • 3-TROPANYL-INDOLE-3-CARBOXYLATE HYDROCHL ORIDE(ICS-205,930, NOVOBAN
  • 3-TROPANYL-INDOLE-3-CARBOXYLATE METHIODI DE ICS-205,930, METHIODI
  • TROPISHTRON HYDROCHLORIDE
  • SS-TROPISETRON
  • 1H-INDOLE-3-CARBOXYLIC ACID, (3-ENDO)-8-METHYL-8-AZABICYCLO [3,2,1]OCT-3-YL ESTER
  • 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-1h-indole-3-carboxylic acid
  • BETA-TROPISETRON
  • TROPICACID
  • Indole-3-carbonyl chloride
  • lαH,5Αh-Tropan-3α-yl indole-3-carboxylate
  • 3-Tropanylindole-3-carboxylate
  • NOVABAN; ICS 205930; SDZ-ICS 930
  • 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride
  • 3H-indole-3-carboxylic acid (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) ester hydrochloride
  • CS-348
  • β-Tropisetron
  • Tropisetron USP/EP/BP
  • rel-(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 1H-indole-3-carboxylate
  • Tropisetron, 10 mM in DMSO
  • 89565-68-4
  • 39565-68-4
  • C17H2N2O2
  • C17H6N2O2