BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT

Product Name: BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
CAS No.: 87779-49-5
Chemical Name: BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
Synonyms: Bz-VGR-AMC;Bz-Val-Gly-Arg-AMC;Benzoyl-Val-Gly-Arg-AMC;BZ-VAL-GLY-ARG-AMC TFA SALT;Bz-Val-Gly-Arg-AMC (I-1085.0050);BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT;N-Benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide;L-Argininamide, N-benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;N-[(2S)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]benzamide
CBNumber: CB3241806
Molecular Formula: C30H37N7O6
Formula Weight: 591.66
MOL File: 87779-49-5.mol

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BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Property

storage temp.: -15°C
solubility: Soluble in DMSO.
form: White powder.
color: White
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB110482
Product name: Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging: 1mg
Price: $80
Updated: 2021/12/16

Chem-Impex

Product number: 32842
Product name: Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging: 5MG
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB110482
Product name: Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging: 2mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB110482
Product name: Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging: 5mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB110482
Product name: Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging: 10mg
Price: $320
Updated: 2021/12/16

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BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Chemical Properties,Usage,Production

Description

Bz-VGR-AMC (87779-49-5) may be used for measuring the trypsin-like activity of the 20S proteasome, in combination with Suc-LLVY-AMC (Cat.# 10-2971, for assaying its chymotrypsin-like activity) and Z-LLE-AMC, (for determining its PGPH activity). Fluorogenic substrate. Ex.: 380nm Em.: 460nm.

Uses

Bz-Val-Gly-Arg-AMC is a bioactive compound used in assaying the degree of inhibition conferred by PS-341, a potent peptidylboronic acid with anticancer properties.

References

[1] FRANK GILLARDON. The 20S proteasome isolated from Alzheimer’s disease brain shows post-translational modifications but unchanged proteolytic activity[J]. Journal of Neurochemistry, 2007, 101 6: 1483-1490. DOI:10.1111/j.1471-4159.2006.04438.x
[2] JEONG-SUN KIM. Navigation Inside a Protease: Substrate Selection and Product Exit in the Tricorn Protease from Thermoplasma acidophilum[J]. Journal of Molecular Biology, 2002, 324 5: Pages 1041-1050. DOI:10.1016/s0022-2836(02)01153-1
[3] BURKHARDT DAHLMANN . Different proteasome subtypes in a single tissue exhibit different enzymatic properties1[J]. Journal of Molecular Biology, 2000, 303 5: Pages 643-653. DOI:10.1006/jmbi.2000.4185
[4] E S LIGHTCAP. Proteasome inhibition measurements: clinical application.[J]. Clinical chemistry, 2000, 46 5: 673-683.

BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Suppliers

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87779-49-5, BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALTRelated Search:

CL 82198 HYDROCHLORIDE BESTATIN HYDROCHLORIDE JC-1 benzyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate:hydrochloride H-ALA-AMC TFA BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT

N-[(2S)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]benzamide

BZ-VAL-GLY-ARG-AMC TFA SALT

BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT

Bz-VGR-AMC

Bz-Val-Gly-Arg-AMC

L-Argininamide, N-benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

N-Benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide

Bz-Val-Gly-Arg-AMC (I-1085.0050)

Benzoyl-Val-Gly-Arg-AMC

87779-49-5

C30H37N7O6

Miscellaneous Enzyme