BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
- Product Name
- BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
- CAS No.
- 87779-49-5
- Chemical Name
- BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
- Synonyms
- Bz-VGR-AMC;Bz-Val-Gly-Arg-AMC;BZ-VAL-GLY-ARG-AMC TFA SALT;Bz-Val-Gly-Arg-AMC (I-1085.0050);BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT;N-Benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide;L-Argininamide, N-benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;N-[(2S)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]benzamide
- CBNumber
- CB3241806
- Molecular Formula
- C30H37N7O6
- Formula Weight
- 591.66
- MOL File
- 87779-49-5.mol
BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Property
- storage temp.
- -15°C
- solubility
- Soluble in DMSO.
- form
- White powder.
- color
- White
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
N-Bromosuccinimide Price
- Product number
- FB110482
- Product name
- Bz-Val-Gly-Arg-AMC trifluoroacetate salt
- Packaging
- 1mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- 32842
- Product name
- Bz-Val-Gly-Arg-AMC trifluoroacetate salt
- Packaging
- 5MG
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FB110482
- Product name
- Bz-Val-Gly-Arg-AMC trifluoroacetate salt
- Packaging
- 2mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FB110482
- Product name
- Bz-Val-Gly-Arg-AMC trifluoroacetate salt
- Packaging
- 5mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FB110482
- Product name
- Bz-Val-Gly-Arg-AMC trifluoroacetate salt
- Packaging
- 10mg
- Price
- $320
- Updated
- 2021/12/16
BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Chemical Properties,Usage,Production
Description
Bz-VGR-AMC (87779-49-5) may be used for measuring the trypsin-like activity of the 20S proteasome, in combination with Suc-LLVY-AMC (Cat.# 10-2971, for assaying its chymotrypsin-like activity) and Z-LLE-AMC, (for determining its PGPH activity). Fluorogenic substrate. Ex.: 380nm Em.: 460nm.
Uses
Bz-Val-Gly-Arg-AMC is a bioactive compound used in assaying the degree of inhibition conferred by PS-341, a potent peptidylboronic acid with anticancer properties.
References
1) Gillardon?et al. (2007),?The 20S proteasome isolated from Alzheimer’s disease brain shows post-translational modifications but unchanged proteolytic activity; J. Neurochem.,?101?1483 2) Kim?et al. (2002),?Navigation inside a protease: substrate selection and product exit in tricorn protease from Thermoplasma acidophilum; J. Mol. Biol.,?324?1041 3) Dahlmann?et al. (2000),?Different proteasome subtypes in a single tissue exhibit different enzymatic properties; J. Mol. Biol.,?303?643 4) Lightcap?et al. (2000),?Proteasome inhibition measurements: clinical application; Clin. Chem.,?46?673
BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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