ChemicalBook > CAS DataBase List > GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE

GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE

Product Name
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE
CAS No.
908844-75-7
Chemical Name
GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE
Synonyms
M871;M871 TFA;WTLNSAGYLLGPEHPPPALALA-NH2;M871, Galanin GAL2 receptor antagonist;GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE;TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLU-HIS-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2;L-Alaninamide, L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-α-glutamyl-L-histidyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-
CBNumber
CB32456352
Molecular Formula
C108H163N27O28
Formula Weight
2287.61
MOL File
908844-75-7.mol
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GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE Property

storage temp. 
Desiccate at -20°C
solubility 
Soluble to 1 mg/ml in 30% acetonitrile
form 
Powder
color 
White to off-white
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
H2N-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Glu-His-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2698
Product name
M871
Packaging
1
Price
$342
Updated
2021/12/16
Usbiological
Product number
255747
Product name
M871
Packaging
1mg
Price
$602
Updated
2021/12/16
ApexBio Technology
Product number
B5327
Product name
M871
Packaging
1mg
Price
$497
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004506
Product name
M871
Purity
95.00%
Packaging
5MG
Price
$500.23
Updated
2021/12/16
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GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE Chemical Properties,Usage,Production

Description

Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists.

Uses

M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 (GalR2) antagonist. M871 exhibits Ki values of 13.1 nM and 420 nM for GalR2 and GalR1, respectively. M871 can be used for research on GalR2-related diseases (such as epilepsy, pain)[1].

storage

Store at -20°C

References

[1] U. E. Sollenberg, et al. M871—A Novel Peptide Antagonist Selectively Recognizing the Galanin Receptor Type 2. Int J Pept Res Ther. 2006;12:2965-2982.

GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE Suppliers

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908844-75-7, GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDERelated Search:

α-Conotoxin MII A-CONOTOXIN AUIB H-SER-PHE-LEU-LEU-ARG-NH2 DABCYL-LYS-HCOV-SARS REPLICASE POLYPROTEIN 1AB (3235-3246)-GLU-EDANS PBP10 leucokinin I H-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-NH2 11-Dideuterolinoleic acid Met-RANTES (human) IKKγ NBD Inhibitory Peptide RAGE antagonist peptide ALPHA-CGRP (8-37) (RAT) GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE

  • GALANIN-(2-13)-GLU-HIS-(PRO)3-(ALA-LEU)2-ALA-AMIDE
  • M871
  • TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-GLU-HIS-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2
  • L-Alaninamide, L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-α-glutamyl-L-histidyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-
  • WTLNSAGYLLGPEHPPPALALA-NH2
  • M871 TFA
  • M871, Galanin GAL2 receptor antagonist
  • 908844-75-7
  • C108H163N27O28