Darunavir ethanolate

Product Name: Darunavir ethanolate
CAS No.: 635728-49-3
Chemical Name: Darunavir ethanolate
Synonyms: Darunavir ethanolate;Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3R,3as,6ar)-hexahydrofuro(2,3-B)furan-3-yl ester, compd. with ethanol (1:1);To the drug;Unii-33o78xf0bw;[14C]-Darunavir ethanolate;Darunavir Ethanolate (100 mg);Darunavir Ethanolate(Prezista);Darunavir Ethanolate (DRV, Prezista);DARUNAVIR ETHANOLATE (TMC114 ETHANOLATE);Darunavir(TMC-114,UIC 94017) Ethanolate
CBNumber: CB32496602
Molecular Formula: C29H43N3O8S
Formula Weight: 593.74
MOL File: 635728-49-3.mol

More

Less

Darunavir ethanolate Property

Melting point:: 98-100°C
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: White

More

Less

Safety

HS Code: 29334900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: D193520
Product name: DarunavirEthanolate
Packaging: 5mg
Price: $150
Updated: 2021/12/16

Usbiological

Product number: 163597
Product name: Darunavir Ethanolate
Packaging: 5mg
Price: $460
Updated: 2021/12/16

TRC

Product number: D193520
Product name: DarunavirEthanolate
Packaging: 50mg
Price: $770
Updated: 2021/12/16

ChemScene

Product number: CS-0750
Product name: DarunavirEthanolate
Purity: 99.92%
Packaging: 100mg
Price: $500
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD64995
Product name: Darunavir Ethanolate
Packaging: 500mg
Price: $175
Updated: 2021/12/16

More

Less

Darunavir ethanolate Chemical Properties,Usage,Production

Uses

Darunavir Ethanolate(Prezista) is an inhibitor of HIV protease. [1] Darunavir was designed to form robust interactions with the protease enzyme from many strains of HIV, including strains from treatment-experienced patients with multiple resistance mutati

Uses

Darunavir Ethanolate (Prezista) is an HIV protease inhibitor. Derivative of Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.

Biological Activity

darunavir ethanolate is a nonpeptidic hiv protease inhibitor approved for the treatment of hiv infection[1].transepithelial transport of darunavir in caco-2 cell monolayers is 2-fold greater in the basal-to-apical direction compared to that in the opposite direction. in l-mdr1 cell, darunavir (121 mm) inhibits p-glycoprotein-mediated efflux of calcein-acetoxymethyl ester[1].darunavir is effective against wild-type and pi-resistant hiv, and has a low oral bioavailability (37%). when used in combination with ritonavir, bioavailability can be increased to 82%[2].[1]. fujimoto h, higuchi m, watanabe h, et al. p-glycoprotein mediates efflux transport of darunavir in human intestinal caco-2 and abcb1 gene-transfected renal llc-pk1 cell lines. biological & pharmaceutical bulletin, 2009, 32(9): 1588-1593.[2]. bhalekar mr, et al. in-vivo bioavailability and lymphatic uptake evaluation of lipid nanoparticulates of darunavir. drug deliv, 2016, 23(7): 2581-2586.

Darunavir ethanolate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Darunavir ethanolate Suppliers

Canada 4 China 159 France 1 Germany 1 India 30 Japan 1 Nepal 1 Spain 1 Switzerland 1 United Kingdom 6 United States 27 Global 232

Jigs chemical

Tel: --
Fax: --
Email: info@jigschemical.com
Country: India
ProdList: 318
Advantage: 58

LAURUS LABS LIMITED

Tel: --
Fax: --
Email: tversosky@lauruslabs.com
Country: India
ProdList: 32
Advantage: 58

Almelo Pvt. Ltd.

Tel: --
Fax: --
Country: India
ProdList: 37
Advantage: 58

ARENE LIFESCIENCES LIMITED

Tel: --
Fax: --
Email: marketing@arenelife.com
Country: India
ProdList: 19
Advantage: 58

Kevy's Labs

Tel: --
Fax: --
Email: kevyslabs@rocketmail.com
Country: India
ProdList: 29
Advantage: 58

Cipla Ltd.

Tel: --
Fax: --
Email: exports@cipla.com
Country: India
ProdList: 72
Advantage: 58

Pharmaffiliates Analytics & Synthetics (P) Ltd.

Tel: --
Fax: --
Email: g@pharmaffiliates.com
Country: India
ProdList: 631
Advantage: 58

Manus Aktteva Biopharma LLP

Tel: --
Fax: --
Country: India
ProdList: 655
Advantage: 58

Clearsynth Labs

Tel: --
Fax: --
Email: fo@clearsynth.com
Country: India
ProdList: 3887
Advantage: 58

Pharma Affiliates

Tel: --
Fax: --
Email: @pharmaffiliates.com
Country: India
ProdList: 6754
Advantage: 58

Athos Chemicals

Tel: --
Fax: --
Email: export@athoschemicals.com
Country: India
ProdList: 315
Advantage: 58

Merix Laboratories Pvt. Ltd

Tel: --
Fax: --
Email: info@merixindia.com
Country: India
ProdList: 132
Advantage: 58

Amtec Health Care Private Limited

Tel: --
Fax: --
Email: nfo@amtechealthcare.com
Country: India
ProdList: 21
Advantage: 58

Hetero Drugs Limited

Tel: --
Fax: --
Country: India
ProdList: 174
Advantage: 58

Anzen Exports

Tel: --
Fax: --
Email: info@anzen.co.in
Country: India
ProdList: 164
Advantage: 58

LUPIN LTD

Tel: --
Fax: --
Email: info@lupin.com
Country: India
ProdList: 191
Advantage: 58

KPS Chemicals & Pharmaceuticals

Tel: --
Fax: --
Email: kpschempharma@gmail.com
Country: India
ProdList: 240
Advantage: 58

Pharmaffiliates Analytics and Synthetics P. Ltd

Tel: --
Fax: --
Email: mktg@pharmaffiliates.com
Country: India
ProdList: 6739
Advantage: 58

SynZeal Research Pvt Ltd

Tel: --
Fax: --
Email: standards@synzeal.com
Country: India
ProdList: 6514
Advantage: 58

MSN LIFE SCIENCES PRIVATE LTD

Tel: --
Fax: --
Email: formulation@msnlabs.com
Country: India
ProdList: 104
Advantage: 58

HETERO LABS LTD

Tel: --
Fax: --
Email: sales@heterodrugs.com
Country: India
ProdList: 97
Advantage: 58

More

Less

View Lastest Price from Darunavir ethanolate manufacturers

Sinoway Industrial co., ltd.

Product: Darunavir ethanolate 635728-49-3
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 0.0099
Supply Ability: 20 tons
Release date: 2021-08-05

Baoji Guokang Bio-Technology Co., Ltd.

Product: Unii-33o78xf0bw 635728-49-3
Price: US $63.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100kg
Release date: 2021-06-04

Zhuozhou Wenxi import and Export Co., Ltd

Product: Unii-33o78xf0bw 635728-49-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

635728-49-3, Darunavir ethanolateRelated Search:

1-epi-Darunavir (3aS,4R,6aR)-Tetrahydro-4-Methoxyfuro[3,4-b]furan-2(3H)-one BIS THF Nitro Derivative 2 Darunavir O-β-D-Glucuronide BIS THF HNS Derivative 3 Repaglinide Pazopanib Hydrochloride 4-Hydroxy Darunavir [(3R,3aS,6aR)-Hydroxyhexahydrofuro[2,3-β]furanyl Succinimidyl Carbonate tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate Darunavir (3R,3αS,6αR)-Hexahydrofuro[2,3-β]furan-3-yl-4-nitrophenyl carbonate 4-AMINO-N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-N-ISOBUTYLBENZENE-1-SULFONAMIDE 4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile GSK1349572 Raltegravir Etravirine Atazanavir sulfate

Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3R,3as,6ar)-hexahydrofuro(2,3-B)furan-3-yl ester, compd. with ethanol (1:1)

Darunavir ethanolate

Unii-33o78xf0bw

N-[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester compd. with ethanol

Darunavir Ethanolate(Prezista)

Darunavir(TMC-114,UIC 94017) Ethanolate

N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl carbamic acid ester, compd. with ethanol (1:1)

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate compound with ethanol (1:1)

[14C]-Darunavir ethanolate

DARUNAVIR ETHANOLATE (TMC114 ETHANOLATE)

Darunavir Ethanolate (DRV, Prezista)

Darunavir EthanolateQ: What is Darunavir Ethanolate Q: What is the CAS Number of Darunavir Ethanolate Q: What is the storage condition of Darunavir Ethanolate Q: What are the applications of Darunavir Ethanolate

To the drug

(3R,3AS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate Ethanolate

Darunavir Ethanolate (100 mg)

635728-49-3

20661-99-1

C29H43N3O8S

C27H37N3O7SC2H6O

C27H37N3O7SC2H5OH

API

Inhibitor

Prezista, TMC114

Other APIs

Inhibitors