((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

Product Name: ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
CAS No.: 874638-80-9
Chemical Name: ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate
Synonyms: (2R)-2-DEOXY-2-FLUORO-2-METHYL-D-ERYTHRO;((2R,3S,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate;(S)-isopropyl 2-(((S)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;SFBM;SF-X1;Sofosbuvir INT 3;Sofosbuvir imp-2;PSI-6130 interMediate;Sofosbuvir Impurity 30;SofosBuvir Impurity 46
CBNumber: CB32514087
Molecular Formula: C20H17FO6
Formula Weight: 372.35
MOL File: 874638-80-9.mol

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((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Property

Melting point:: 133℃
Boiling point:: 458.6±34.0 °C(Predicted)
Density: 1.33
storage temp.: 2-8°C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: D232985
Product name: (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonicAcidγ-Lactone3,5-Dibenzoate
Packaging: 25g
Price: $165
Updated: 2021/12/16

TRC

Product number: D232985
Product name: (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonicAcidγ-Lactone3,5-Dibenzoate
Packaging: 50g
Price: $275
Updated: 2021/12/16

Usbiological

Product number: 293138
Product name: 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone
Packaging: 2g
Price: $319
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MD09387
Product name: 3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone
Packaging: 100g
Price: $410
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2H23-3-13
Product name: ((2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methylbenzoate
Packaging: 100g
Price: $295
Updated: 2021/12/16

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((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Chemical Properties,Usage,Production

Uses

neuromuscular blocking agent

Uses

(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic Acid γ-Lactone 3,5-Dibenzoate is a reactant used in the synthesis of 1''-C-cyano-2''-fluoro-2''-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.

Application

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate is an impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir.

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate Suppliers

China 284 India 8 United Kingdom 1 United States 16 Global 309

BOC Sciences

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Aladdin Scientific

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Aceschem Inc.

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View Lastest Price from ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate 874638-80-9
Price: US $0.01-1.00/KG
Min. Order: 10g
Purity: 99%+
Supply Ability: 10000KG
Release date: 2019-12-25

WUHAN FORTUNA CHEMICAL CO., LTD

Product: ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate 874638-80-9
Price: US $0.00-0.00/KG
Min. Order: 100g
Purity: 98%min
Supply Ability: 100kgs
Release date: 2021-08-30

Henan Bao Enluo International TradeCo.，LTD

Product: ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate 874638-80-9
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500t/month
Release date: 2023-08-17

874638-80-9, ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoateRelated Search:

D-Alanine, N-[[P(S),2'R]-2'-cyano-2'-deoxy-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI) Sofosbuvir Impurity 17 L-Alanine, N-[(R)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-Methylethyl ester (3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester L-Alanine isopropyl ester hydrochloride (2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate PSI-6130 derivative D-Arabinonic acid, 2-C-methyl-4,5-O-(1-methylethylidene)-,ethyl ester 2'-deoxy-2'-fluoro-2'-C-methyluridine Sofosbuvir alpha-D-erythro-Pentofuranous-2-ulose 1,3,5-tribenzoate sofosBuvir impurity 36 SofosBuvir Impurity 55 Sofosbuvir impurity E SofosBuvir Impurity 40 SofosBuvir Impurity 54

3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-ribono-γ-latone

SFBM

(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid γ-lactone 3,5-dibenzoate

Sofosbuvir intermediate

Sofosbuvir Impurity 30

3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-ribono-1,4-lactone

(2R,3R,4R)-2-[(benzoyloxy)methyl]-4-fluoro-4-methyl-5-oxooxolan-3-yl benzoate

Sofosbuvir Intermediate 1

Sofosbuvir INT 3

((2R,3S,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate

(2R)-2-Deoxy-2-fluoro-2-methy-D- erythropentonic acid gamma-lactone 3,5- dibenzoate

nterMediate of Sofosbuvir

Di-O-benzoyl-2-deoxy-2-fluoro-2-C-Methyl-D

Sofosbuvir imp-2

3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-C-methyl-D-ribono-γ-latone

4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one

(S)-isopropyl 2-(((S)-(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

(2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythro-pentonic acid-g-lactone 3,5-dibenzoate

Methyl ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetrahydrofuran-2-yl) benzoate

(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythropentonic acid gamma-lactone 3,5-dibenzoate

PSI-6130 interMediate

(2R)-2-DEOXY-2-FLUORO-2-METHYL-D-ERYTHRO

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-C-Methyl-D-ribono-γ-lactone

D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-Methyl-, γ-lactone, 3,5-dibenzoate, (2R)-

(2R)-2-Deoxy-2-fluoro-2-Methyl-D-erythropentonic acid

InterMediate of Sofosbuvir

3. ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-Methyl-5-oxotetra

SofosBuvir Impurity 46

3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2C-methyl-D-arabino-1,4-lactone

(2R-3R,4R)-3-(Benzoyzxy)-4-Fluoro-4-Methyl-5-Oxotetrahydrofuran-2Yl)Methyl Benzoate

Sofosbuvir Impurity 101

SF-X1

((2R,3R,4R)-3-(BENZOYLOXY)-4-FLUORO-4-METHYL-5-OXOTETRAHYDROFURAN-2-YL)METHYL BENZOATE 874638-80-9

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate ISO 9001：2015 REACH

((2R,3R,4R)-3-(DENZOYLOXY)-4-FLUORO-4-METHYL-5-OXOTETRAHYDROFURAN-2-YL)METHYL BENZOATE

((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydro...

(2R,3R,4R)-3- (benzoyoxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2yl)methyl Benzoate, 98%

(2R)-3,5-di-O-benzoyl-2-fluoro-2-C-methyl-D-ribono-r-lactone

874638-80-9

1334518-02-8

874638-08-9

C20H17FO6

C20H17O6F

apis

Sofosbuvir intermediate