Zonisamide sodium salt
- Product Name
- Zonisamide sodium salt
- CAS No.
- 68291-98-5
- Chemical Name
- Zonisamide sodium salt
- Synonyms
- ZON;ZonisaMide (sodiuM);Zonisamide sodium salt;Excegram sodium-potassium salt;Exceglan sodium-potassium salt;Aleviatin sodium-potassium salt;1,2-BENZISOXAZOLE-3-METHANESULFONAMIDE;BENZO[D]ISOXAZOL-3-YL-METHANESULFONAMIDE;1,2-Benzisoxazole-3-methanesulfonamide sodium salt;1,2-benzisoxazole-3-methanesulfonamide sodium-potassium salt
- CBNumber
- CB3252442
- Molecular Formula
- C8H7N2NaO3S
- Formula Weight
- 234.21
- MOL File
- 68291-98-5.mol
Zonisamide sodium salt Property
- storage temp.
- Store at -20°C
- solubility
- H2O: >5mg/mL
- form
- powder
- color
- white to beige
- Water Solubility
- H2O: >5mg/mL
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- Z2001
- Product name
- Zonisamide sodium salt
- Purity
- ≥98% (HPLC), powder
- Packaging
- 10mg
- Price
- $342
- Updated
- 2025/07/31
- Product number
- Z2001
- Product name
- Zonisamide sodium salt
- Purity
- ≥98% (HPLC), powder
- Packaging
- 100mg
- Price
- $2220
- Updated
- 2025/07/31
- Product number
- Z700018
- Product name
- Zonisamide sodium salt
- Packaging
- 25mg
- Price
- $345
- Updated
- 2021/12/16
- Product number
- B1231
- Product name
- Zonisamidesodium
- Packaging
- 10mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- B1231
- Product name
- Zonisamidesodium
- Packaging
- 200mg
- Price
- $82
- Updated
- 2021/12/16
Zonisamide sodium salt Chemical Properties,Usage,Production
Uses
Zonisamide Sodium Salt can be used in biological study of neuroprotective effects of zonisamide target astrocyte. It shows neuroprotection by increasing glutathione, cystine/glutamate exchange transporter expression in mouse CNS catecholaminergic, astrocyte and rat glioma cell and mouse model of 6-OHDA induced hemi-Parkinson''s disease
Biochem/physiol Actions
Zonisamide sodium salt is an anti-epileptic. It is effective in various animal epilepsy models and humans with both partial and generalized epileptic seizures. Zonisamide sodium salt also scavenges nitric oxide (NO).
in vivo
Zonisamide sodium (40 mg/kg; i.p.; single daily for 14 days) prevents seizures in FeCl3-induced chronic amygdalar seizures model[2].
Zonisamide sodium (14, 28, 56 mg/kg; i.p.; single daily for 6 weeks) alleviates cardiac hypertrophy and improved cardiac function in rats subjected to AAC (abdominal aortic constriction)[3].
Zonisamide sodium (14, 28, 56 mg/kg; i.p.; single daily for 6 weeks) upregulates Hrd1 expression and accelerates ERAD in the hearts of AAC rats[3].
| Animal Model: | Male Wistar rats (200-250 g; FeCl3-induced chronic amygdalar seizures)[2]. |
| Dosage: | 40 mg/kg |
| Administration: | Intraperitoneal injection; single daily for 14 days. |
| Result: | Showed activity of anti-seizures. Significantly down-regulated GABA transporters GAT-1 in the hippocampus. |
| Animal Model: | Adult male Sprague-Dawley rats (100-120 g; cardiac hypertrophy model)[3]. |
| Dosage: | 14, 28, 56 mg/kg (dissolved in 1% DMSO) |
| Administration: | Intraperitoneal injection; single daily for 6 weeks. |
| Result: | Significantly attenuated cardiac hypertrophy and fibrosis. Increased LV ejection fraction (EF), fractional shortening (FS) and E/A ratio. Markedly increased the expression of Hrd1 in the hearts of AAC rats. |
Zonisamide sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Zonisamide sodium salt manufacturers
- Product
- Zonisamide sodium 68291-98-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- Zonisamide sodium 68291-98-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- Zonisamide sodium salt 68291-98-5
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20ton
- Release date
- 2019-12-20