Uses
ChemicalBook > CAS DataBase List > 3-HYDROXYPHTHALIC ANHYDRIDE

3-HYDROXYPHTHALIC ANHYDRIDE

Uses
Product Name
3-HYDROXYPHTHALIC ANHYDRIDE
CAS No.
37418-88-5
Chemical Name
3-HYDROXYPHTHALIC ANHYDRIDE
Synonyms
4-HYDROXY-ISOBENZOFURAN-1,3-DIONE;Nsc 80858;Brn 0135783;3-HydroxyphthaL;3-hydroxy-phthalicanhydrid;3-hydroxyphtalic anhydride;3-HYDROXYPHTHALIC ANHYDRIDE;Phthalic anhydride, 3-hydroxy-;4-hydroxy-3-isobenzofurandione;3-HYDROXYPHTHALIC ACID ANHYDRIDE
CBNumber
CB3253702
Molecular Formula
C8H4O4
Formula Weight
164.12
MOL File
37418-88-5.mol
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3-HYDROXYPHTHALIC ANHYDRIDE Property

Melting point:
199-202 °C (lit.)
Boiling point:
365.4±25.0 °C(Predicted)
Density 
1.624±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Acetonitrile (Slightly), DMSO (Slightly)
pka
6.25±0.20(Predicted)
form 
Powder
color 
White to beige
BRN 
135783
Stability:
Hygroscopic
InChI
InChI=1S/C8H4O4/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3,9H
InChIKey
CCTOEAMRIIXGDJ-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C(O)=CC=C2)C(=O)O1
CAS DataBase Reference
37418-88-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
TI3300000
21
HS Code 
29182900
Toxicity
mouse,LD50,intravenous,75mg/kg (75mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#08845,
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
308021
Product name
3-Hydroxyphthalic anhydride
Purity
98%
Packaging
1g
Price
$120.4
Updated
2024/03/01
TRC
Product number
H951270
Product name
3-Hydroxyphthalic anhydride
Packaging
2.5g
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
2H26-1-33
Product name
3-Hydroxyphthalic anhydride
Purity
97%
Packaging
5G
Price
$109
Updated
2021/12/16
Oakwood
Product number
222694
Product name
4-Hydroxyisobenzofuran-1,3-dione
Packaging
250mg
Price
$20
Updated
2021/12/16
BroadPharm
Product number
BP-13154
Product name
3-Hydroxyphthalic anhydride
Purity
98%
Packaging
250mg
Price
$35
Updated
2021/12/16
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3-HYDROXYPHTHALIC ANHYDRIDE Chemical Properties,Usage,Production

Uses

3-Hydroxyphthalic Anhydride is used to synthesize 3-Hydroxyphthalic Anhydride-modified human serum albumin which has high potency as a microbicide for prevention of the sexual transmission of HIV. It is also used as a reagent in organic synthesis of other compounds including that of inhibitors of NF-κB derived from thalidomide.

Chemical Properties

Beige powder

Uses

3-Hydroxyphthalic Anhydride is used to synthesize 3-Hydroxyphthalic Anhydride-modified human serum albumin whichhas high potency as a microbicide for prevention of the sexual transmission of HIV. It is also used as a reagent in organicsynthesis of other compounds including that of inhibitors of NF-κB derived from thalidomide.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 5092, 1955 DOI: 10.1021/ja01624a042
Synthesis, p. 788, 1985 DOI: 10.1055/s-1985-31350

3-HYDROXYPHTHALIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-HYDROXYPHTHALIC ANHYDRIDE Suppliers

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View Lastest Price from 3-HYDROXYPHTHALIC ANHYDRIDE manufacturers

Asia Chem I and E (Jiangsu) Co Ltd
Product
3-Hydroxyphthalic anhydride 37418-88-5
Price
US $125.58/Kg/Drum
Min. Order
25Kg/Drum
Purity
98.00%HPLC
Supply Ability
1ton/month
Release date
2021-09-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
3-HYDROXYPHTHALIC ANHYDRIDE 37418-88-5
Price
US $10.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2021-05-17
Hebei Mojin Biotechnology Co., Ltd
Product
3-HYDROXYPHTHALIC ANHYDRIDE 37418-88-5
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000KG
Release date
2023-08-24

37418-88-5, 3-HYDROXYPHTHALIC ANHYDRIDERelated Search:


  • 4-HYDROXY-ISOBENZOFURAN-1,3-DIONE
  • 3-HYDROXYPHTHALIC ACID ANHYDRIDE
  • 3-HYDROXYPHTHALIC ANHYDRIDE
  • 3-hydroxy-phthalicanhydrid
  • 4-hydroxy-3-isobenzofurandione
  • 1,3-Isobenzofurandione, 4-hydroxy-
  • Brn 0135783
  • Nsc 80858
  • Phthalic anhydride, 3-hydroxy-
  • 4-hydroxy-1,3-dihydro-2-benzofuran-1,3-dione
  • 4-Hydroxy-2-benzofuran-1,3-dione
  • 3-HYDROXYPHTHALIC ANHYDRIDE 97+%
  • 4-Hydroxy-1,3-isobenzofurandione
  • 3-HydroxyphthaL
  • 3-hydroxyphtalic anhydride
  • 3-HYDROXYPHTHALIC ANHYDRIDE ISO 9001:2015 REACH
  • 3-Hydroxyphthalic anhydride 4-Chlorophthalic anhydride
  • 37418-88-5
  • Organic Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Building Blocks
  • Anhydride Monomers
  • Monomers
  • Polymer Science
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Organic Building Blocks
  • Phthalic Acids, Esters and Derivatives
  • 37418-88-5