N3-PEG1-CH2CH2NH2
- Product Name
- N3-PEG1-CH2CH2NH2
- CAS No.
- 464190-91-8
- Chemical Name
- N3-PEG1-CH2CH2NH2
- Synonyms
- N3-PEG1-NH2;H2N-C2-PEG1-N3;Azido-PEG1-NH2;Amino-PEG2-azide;Azido-PEG1-Amine;N3-PEG1-CH2CH2NH2;Azido-PEG1-CH2CH2NH2;2-(2-Azidoethoxy)ethanamine;2-(2-azidoethoxy)ethan-1-amine;Azido-PEG1-amine,2-(2-azidoethoxy)ethanamine
- CBNumber
- CB32603839
- Molecular Formula
- C4H11N4O+
- Formula Weight
- 131.15634
- MOL File
- 464190-91-8.mol
N3-PEG1-CH2CH2NH2 Property
- storage temp.
- Amber Vial, Refrigerator, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Oil
- color
- Colourless to Off-White
- Appearance
- yellowish oil
- InChI
- InChI=1S/C4H11N4O/c5-1-3-9-4-2-7-8-6/h6H,1-5H2/q+1
- InChIKey
- BJMOEXHRQCURAG-UHFFFAOYSA-N
- SMILES
- O(C([H])([H])C([H])([H])N=[N+]=N[H])C([H])([H])C([H])([H])N([H])[H]
N-Bromosuccinimide Price
- Product number
- A965463
- Product name
- Azido-PEG1-amine
- Packaging
- 50mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- BP-21611
- Product name
- Azido-PEG1-amine
- Purity
- 98%
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 282907
- Product name
- N3-PEG1-CH2CH2NH2
- Packaging
- 1g
- Price
- $361
- Updated
- 2021/12/16
- Product number
- POL0002351
- Product name
- AZIDO-PEG1-AMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.08
- Updated
- 2021/12/16
- Product number
- BP-21611
- Product name
- Azido-PEG1-amine
- Purity
- 98%
- Packaging
- 1g
- Price
- $580
- Updated
- 2021/12/16
N3-PEG1-CH2CH2NH2 Chemical Properties,Usage,Production
Description
Azido-PEG1-amine is a heterobifunctional linker containing an amino(NH2)and an azide (N3) group. The amino group is reactive with carboxylic acids, activated NHS esters,. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
Uses
Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N3-PEG1-CH2CH2NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N3-PEG1-CH2CH2NH2 manufacturers
- Product
- azido-PEG1-amine 464190-91-8
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-23