ChemicalBook > CAS DataBase List > N3-PEG1-CH2CH2NH2

N3-PEG1-CH2CH2NH2

Product Name
N3-PEG1-CH2CH2NH2
CAS No.
464190-91-8
Chemical Name
N3-PEG1-CH2CH2NH2
Synonyms
N3-PEG1-NH2;H2N-C2-PEG1-N3;Azido-PEG1-NH2;Amino-PEG2-azide;Azido-PEG1-Amine;N3-PEG1-CH2CH2NH2;Azido-PEG1-CH2CH2NH2;2-(2-Azidoethoxy)ethanamine;2-(2-azidoethoxy)ethan-1-amine;Azido-PEG1-amine,2-(2-azidoethoxy)ethanamine
CBNumber
CB32603839
Molecular Formula
C4H11N4O+
Formula Weight
131.15634
MOL File
464190-91-8.mol
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N3-PEG1-CH2CH2NH2 Property

storage temp. 
Amber Vial, Refrigerator, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Oil
color 
Colourless to Off-White
Appearance
yellowish oil
InChI
InChI=1S/C4H11N4O/c5-1-3-9-4-2-7-8-6/h6H,1-5H2/q+1
InChIKey
BJMOEXHRQCURAG-UHFFFAOYSA-N
SMILES
O(C([H])([H])C([H])([H])N=[N+]=N[H])C([H])([H])C([H])([H])N([H])[H]
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A965463
Product name
Azido-PEG1-amine
Packaging
50mg
Price
$100
Updated
2021/12/16
BroadPharm
Product number
BP-21611
Product name
Azido-PEG1-amine
Purity
98%
Packaging
100mg
Price
$250
Updated
2021/12/16
ChemPep
Product number
282907
Product name
N3-PEG1-CH2CH2NH2
Packaging
1g
Price
$361
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002351
Product name
AZIDO-PEG1-AMINE
Purity
95.00%
Packaging
5MG
Price
$497.08
Updated
2021/12/16
BroadPharm
Product number
BP-21611
Product name
Azido-PEG1-amine
Purity
98%
Packaging
1g
Price
$580
Updated
2021/12/16
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N3-PEG1-CH2CH2NH2 Chemical Properties,Usage,Production

Description

Azido-PEG1-amine is a heterobifunctional linker containing an amino(NH2)and an azide (N3) group. The amino group is reactive with carboxylic acids, activated NHS esters,. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Uses

Azido-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N3-PEG1-CH2CH2NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N3-PEG1-CH2CH2NH2 manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
azido-PEG1-amine 464190-91-8
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-23