McMMAD

Product Name: McMMAD
CAS No.: 1401963-15-2
Chemical Name: McMMAD
Synonyms: McMMAD;Mc-MMAD;Mc MMAD;MC MMAD; MCMMAD;N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide;L-Valinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-
CBNumber: CB32666656
Molecular Formula: C51H77N7O9S
Formula Weight: 964.26358
MOL File: 1401963-15-2.mol

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McMMAD Property

Boiling point:: 1054.1±65.0 °C(Predicted)
Density: 1.168±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C,unstable in solution, ready to use.
solubility: DMSO: ≥ 100 mg/mL (103.71 mM); Water: < 0.1 mg/mL (insoluble)
form: Powder
pka: 13.63±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-1615
Product name: Mc-MMAD
Purity: 98.50%
Packaging: 1mg
Price: $660
Updated: 2021/12/16

ChemScene

Product number: CS-1615
Product name: Mc-MMAD
Purity: 98.50%
Packaging: 5mg
Price: $1116
Updated: 2021/12/16

ChemScene

Product number: CS-1615
Product name: Mc-MMAD
Purity: 98.50%
Packaging: 10mg
Price: $1710
Updated: 2021/12/16

Crysdot

Product number: CD31003618
Product name: Mc-MMAD
Purity: 98+%
Packaging: 1mg
Price: $750
Updated: 2021/12/16

Chemenu

Product number: CM190456
Product name: Mc-MMAD
Purity: 98%
Packaging: 10mg
Price: $868
Updated: 2021/12/16

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McMMAD Chemical Properties,Usage,Production

Uses

Mc-MMAD is a protective group (maleimidocaproyl)-conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a agent-linker conjugate for ADC.

IC 50

Auristatin

References

[1] Antibody-drug conjugates Patent: WO 2013068874 A1

McMMAD Preparation Products And Raw materials

Raw materials

Preparation Products

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McMMAD Suppliers

China 70 United States 5 Global 75

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9520
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Nanjing Dulai Biotechnology Co., Ltd.

Tel: 025-84699383-8003;025-846993838003-8003 18013301593;18013301590
Fax: 025-84699383-8003
Email: njduly@126.com
Country: China
ProdList: 3293
Advantage: 55

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 925
Advantage: 55

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 50266790 18317173152
Fax: QQ3382968513
Email: Hailey@shsendpharm.com
Country: China
ProdList: 904
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

1401963-15-2, McMMADRelated Search:

VcMMAD MonoMethylauristatin F McMMAE MC-MMAF MonoMethyl Dolastatin 10

Mc MMAD

McMMAD

Mc-MMAD

N-[6-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide

MC MMAD; MCMMAD

L-Valinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-

1401963-15-2

C51H77N7O9S

ADCs

ADC LINKER