FOLINIC ACID CALCIUM SALT PENTAHYDRATE
- Product Name
- FOLINIC ACID CALCIUM SALT PENTAHYDRATE
- CAS No.
- 41927-89-3
- Chemical Name
- FOLINIC ACID CALCIUM SALT PENTAHYDRATE
- Synonyms
- LEUCOVORIN PENTAHYDRATE;CALCIUM FOLINATE PENTAHYDRATE;LEUCOVORIN CALCIUM SALT PENTAHYDRATE;FOLINIC ACID CALCIUM SALT PENTAHYDRATE;5-HCO-H4PTEGLU CALCIUM SALT PENTAHYDRATE;CITROVORUM FACTOR CALCIUM SALT PENTAHYDRATE;FOLINIC ACID CALCIUM SALT PENTAHYDRATE USP/EP/BP;5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT;5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT PENTAHYDRATE;5-FORMYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID CALCIUM SALT PENTAHYDRATE
- CBNumber
- CB3269631
- Molecular Formula
- C20H31CaN7O12
- Formula Weight
- 601.58
- MOL File
- 41927-89-3.mol
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Property
- Melting point:
- 240-250 °C
- storage temp.
- 0-6°C
- solubility
- Aqueous (Slightly, Sonicated), Water (Sparingly, Heated, Sonicated)
- form
- Solid
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
Safety
- Safety Statements
- 24/25
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P285In case of inadequate ventilation wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- L2023
- Product name
- Leucovorin Calcium Salt Pentahydrate
- Packaging
- 100mg
- Price
- $418
- Updated
- 2021/12/16
- Product number
- ING0006721
- Product name
- CALCIUM FOLINATE PENTAHYDRATE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $679.14
- Updated
- 2021/12/16
- Product number
- ING0006721
- Product name
- CALCIUM FOLINATE PENTAHYDRATE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1612.96
- Updated
- 2021/12/16
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Chemical Properties,Usage,Production
Uses
Anti-anemic (folate deficiency); antidote (to folic acid antagonists).
brand name
Wellcovorin (GlaxoSmithKline).
Clinical Use
Folinic acid rescue
Enhancement of 5-fluorouracil cytotoxicity in
advanced colorectal cancer
Folate deficiency
Drug interactions
Potentially hazardous interactions with other drugs
Should not be administered simultaneously with a
folic acid antagonist as this may nullify the effect of
the antagonist.
Cytotoxics: avoid with panitumumab and raltitrexed.
Metabolism
Folinic acid is a racemate where the L-form (L-5-
formyl-tetrahydrofolate, L-5-formyl-THF), is the active
enantiomer. The major metabolic product of folinic acid
is 5-methyl-tetrahydrofolic acid (5-methyl-THF) which
is predominantly produced in the liver and intestinal
mucosa.
80-90% with the urine (5- and 10-formyltetrahydrofolates
inactive metabolites), 5-8% with the
faeces.
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Suppliers
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View Lastest Price from FOLINIC ACID CALCIUM SALT PENTAHYDRATE manufacturers
- Product
- FOLINIC ACID CALCIUM SALT PENTAHYDRATE 41927-89-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-07-30