FOLINIC ACID CALCIUM SALT PENTAHYDRATE
- Product Name
- FOLINIC ACID CALCIUM SALT PENTAHYDRATE
- CAS No.
- 41927-89-3
- Chemical Name
- FOLINIC ACID CALCIUM SALT PENTAHYDRATE
- Synonyms
- LEUCOVORIN PENTAHYDRATE;CALCIUM FOLINATE PENTAHYDRATE;LEUCOVORIN CALCIUM SALT PENTAHYDRATE;FOLINIC ACID CALCIUM SALT PENTAHYDRATE;5-HCO-H4PTEGLU CALCIUM SALT PENTAHYDRATE;CITROVORUM FACTOR CALCIUM SALT PENTAHYDRATE;FOLINIC ACID CALCIUM SALT PENTAHYDRATE USP/EP/BP;5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT;5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT PENTAHYDRATE;5-FORMYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID CALCIUM SALT PENTAHYDRATE
- CBNumber
- CB3269631
- Molecular Formula
- C20H31CaN7O12
- Formula Weight
- 601.58
- MOL File
- 41927-89-3.mol
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Property
- Melting point:
- 240-250 °C
- storage temp.
- 0-6°C
- solubility
- Aqueous (Slightly, Sonicated), Water (Sparingly, Heated, Sonicated)
- form
- Solid
- color
- Off-White to Pale Yellow
- Stability:
- Hygroscopic
Safety
- Safety Statements
- 24/25
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P285In case of inadequate ventilation wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- L2023
- Product name
- Leucovorin Calcium Salt Pentahydrate
- Packaging
- 100mg
- Price
- $418
- Updated
- 2021/12/16
- Product number
- ING0006721
- Product name
- CALCIUM FOLINATE PENTAHYDRATE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $679.14
- Updated
- 2021/12/16
- Product number
- ING0006721
- Product name
- CALCIUM FOLINATE PENTAHYDRATE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1612.96
- Updated
- 2021/12/16
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Chemical Properties,Usage,Production
Uses
Anti-anemic (folate deficiency); antidote (to folic acid antagonists).
brand name
Wellcovorin (GlaxoSmithKline).
Clinical Use
Folinic acid rescue
Enhancement of 5-fluorouracil cytotoxicity in
advanced colorectal cancer
Folate deficiency
Drug interactions
Potentially hazardous interactions with other drugs
Should not be administered simultaneously with a
folic acid antagonist as this may nullify the effect of
the antagonist.
Cytotoxics: avoid with panitumumab and raltitrexed.
Metabolism
Folinic acid is a racemate where the L-form (L-5-
formyl-tetrahydrofolate, L-5-formyl-THF), is the active
enantiomer. The major metabolic product of folinic acid
is 5-methyl-tetrahydrofolic acid (5-methyl-THF) which
is predominantly produced in the liver and intestinal
mucosa.
80-90% with the urine (5- and 10-formyltetrahydrofolates
inactive metabolites), 5-8% with the
faeces.
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
FOLINIC ACID CALCIUM SALT PENTAHYDRATE Suppliers
View Lastest Price from FOLINIC ACID CALCIUM SALT PENTAHYDRATE manufacturers
- Product
- FOLINIC ACID CALCIUM SALT PENTAHYDRATE 41927-89-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-07-30