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SOLASONINE

Product Name
SOLASONINE
CAS No.
19121-58-5
Chemical Name
SOLASONINE
Synonyms
SOLASONIN;PURAPURIN;NSC 82149;SOLANINE S;PURAPURINE;SOLASONINE;SOLANCARPIN;Solasoonine;SOLASODAMINE;α-Solasonine
CBNumber
CB3274987
Molecular Formula
C45H73NO16
Formula Weight
884.07
MOL File
19121-58-5.mol
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SOLASONINE Property

Melting point:
301-303℃
alpha 
D23 -88° (c = 1.01 in pyridine); D22 -74.5° (c = 0.51 in methanol)
Density 
1.42
solubility 
DMSO : 100 mg/mL (113.11 mM; Need ultrasonic)
form 
powder
pka
12.78±0.70(Predicted)
color 
White-beige
InChIKey
QCTMYNGDIBTNSK-YQBIRKIONA-N
LogP
4.350 (est)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

TRC
Product number
S676600
Product name
α-Solasonine
Packaging
1mg
Price
$115
Updated
2021/12/16
Usbiological
Product number
300993
Product name
Solasonine
Packaging
10mg
Price
$390
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594310
Product name
Solasonine
Packaging
20mg
Price
$391
Updated
2021/12/16
Biorbyt Ltd
Product number
orb104521
Product name
Solasonine
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb594310
Product name
Solasonine
Packaging
100mg
Price
$799
Updated
2021/12/16
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SOLASONINE Chemical Properties,Usage,Production

Description

This gly<:oalkaloid occurs in several species of Solanum including S. aviculare, S. sodomeum, S. verbascifolium and S. xanthocarpum. The alkaloid crystallizes from 80 per cent EtOH with 4.5 H20, m.p. 245-250°C (dec.), the anhydrous form being obtained from absolute MeOH. It has [α]25D - 68° (EtOH) and yields the following salts: hydrochloride, m.p. 265°C; picrate, m.p. 199-201 °C; picrolonate, m.p. 230-loC and the acetyl derivative, m.p. l35-8°C. On alkaline hydrolysis, the alkaloid gives solasodine and one mole each of galactose, glucose and rhamnose. The solution in concentrated H2S04 eventually gives a crimson colour with a brown fluorescence.

Chemical Properties

Soluble in hot ethanol and hot dioxane, slightly soluble in hot water and dilute acetic acid, insoluble in chloroform and ether. Derived from the fruit of Solanum aviculare Forst., a plant of the Solanaceae family.

Uses

α-Solasonine is a natural glycoalkaloid compound which has been shown to inhibit Gli-mediated transcritional activity.

Definition

ChEBI: Solasonine is an azaspiro compound, an oxaspiro compound and a steroid.

Purification Methods

Solasonine crystallises from aqueous 80% dioxane or MeOH in needles. [Bell & Briggs J Chem Soc 1 1942, Briggs et al. J Chem Soc 4645 1961, Briggs et al. J Chem Soc 2848 1963.] The picrate crystallises from 30% aqueous EtOH with m 197-198o(dec) [Briggs & Cambie J Chem Soc 1422 1958]. [Beilstein 27 III/IV 2006.]

References

Oddo et a/., Gazzetta, 35, 27 (1905)
Levi., J. Soc. Chem. Ind., 49, 395T (1930)
Briggs., Nature, 144, 247 (1939)
Briggs.,J. Chem. Soc., 3 (1942)
Briggs, Vining., ibid, 2809 (1953)
Hayes, Scaforth., ibid, 74S (1963)

SOLASONINE Preparation Products And Raw materials

Raw materials

Preparation Products

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SOLASONINE Suppliers

China 213 Germany 1 India 3 United Kingdom 7 United States 21 USA 1 Global 246
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6003
Advantage
61
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
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View Lastest Price from SOLASONINE manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
SOLASONINE 19121-58-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-24
Shanghai Standard Technology Co., Ltd.
Product
Solasonine 19121-58-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-22
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Solasonine 19121-58-5 19121-58-5
Price
US $52.00/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-18

19121-58-5, SOLASONINERelated Search:

Solamargine SOLASODINE Monomelittoside Gypenoside L Angoroside C (2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside D-Galactose 2-(2-DODECYLOXYETHOXY)ETHANOL 2-(HEXADECYLOXY)ETHANOL SEC-BUTYL ETHER 12-AMINO-1-DODECANOL 1,1,2-TRIETHOXYETHANE Cyclopentamine CHOLESTERYL ETHYL ETHER Dipropylene glycol monomethyl ether Citronellol 2-(DODECYLOXY)ETHANOL Cholesterol

  • Solasonine alpha-Solasonine
  • NSC 82149
  • PURAPURIN
  • PURAPURINE
  • SOLANINE S
  • SOLANCARPIN
  • Solasonine 19121-58-5
  • SOLASODAMINE
  • SOLASONIN
  • SOLASONINE
  • 5-SOLASODEN-3BETA-OL 3-O-6-D-DEOXY-ALPHA-L-MONOPYRANOSYL (1->2)-BETA-D-GLUCOPYRANOSYL (1->3)-BETA-D-GALACTOPYRANOSIDE
  • .beta.-D-Galactopyranoside, (3.beta.,22.alpha.,25R)-spirosol-5-en-3-yl O-6-deoxy-.alpha.-L-mannopyranosyl-(1?2)-O-.beta.-D-glucopyranosyl-(1?3)-
  • SOLASONINE(RG)
  • [(22R,25R)-Spirosol-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-galactopyranoside
  • Solasoonine
  • ALPHA-SOLASONINE
  • β-D-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-
  • α-Solasonine
  • (2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-(((2'S,4S,5'R,6aR,6bS,8aS,8bR,9S,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Solasonine extrapure, 98%
  • Solasonine (6CI, 7CI, 8CI)
  • (2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-Hydroxy-2-(hydroxymethyl)-6-(((4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • α-Solasonine-RM
  • (2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-Hydroxy-2-(hydroxymethyl)-6-(((4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • 19121-58-5
  • C45H73NO16
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Alkaloids