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SOLASONINE

Product Name
SOLASONINE
CAS No.
19121-58-5
Chemical Name
SOLASONINE
Synonyms
SOLASONIN;PURAPURIN;NSC 82149;SOLANINE S;PURAPURINE;SOLASONINE;SOLANCARPIN;Solasoonine;SOLASODAMINE;α-Solasonine
CBNumber
CB3274987
Molecular Formula
C45H73NO16
Formula Weight
884.07
MOL File
19121-58-5.mol
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SOLASONINE Property

Melting point:
301-303℃
alpha 
D23 -88° (c = 1.01 in pyridine); D22 -74.5° (c = 0.51 in methanol)
Density 
1.42
solubility 
DMSO : 100 mg/mL (113.11 mM; Need ultrasonic)
form 
powder
pka
12.78±0.70(Predicted)
color 
White-beige
InChIKey
QCTMYNGDIBTNSK-YQBIRKIONA-N
LogP
4.350 (est)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

TRC
Product number
S676600
Product name
α-Solasonine
Packaging
1mg
Price
$115
Updated
2021/12/16
Usbiological
Product number
300993
Product name
Solasonine
Packaging
10mg
Price
$390
Updated
2021/12/16
Biosynth Carbosynth
Product number
OS65589
Product name
Solasonine
Packaging
1mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
OS65589
Product name
Solasonine
Packaging
2mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
Y0195
Product name
Solasonine
Packaging
1mg
Price
$117
Updated
2021/12/16
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SOLASONINE Chemical Properties,Usage,Production

Description

This gly<:oalkaloid occurs in several species of Solanum including S. aviculare, S. sodomeum, S. verbascifolium and S. xanthocarpum. The alkaloid crystallizes from 80 per cent EtOH with 4.5 H20, m.p. 245-250°C (dec.), the anhydrous form being obtained from absolute MeOH. It has [α]25D - 68° (EtOH) and yields the following salts: hydrochloride, m.p. 265°C; picrate, m.p. 199-201 °C; picrolonate, m.p. 230-loC and the acetyl derivative, m.p. l35-8°C. On alkaline hydrolysis, the alkaloid gives solasodine and one mole each of galactose, glucose and rhamnose. The solution in concentrated H2S04 eventually gives a crimson colour with a brown fluorescence.

Chemical Properties

Soluble in hot ethanol and hot dioxane, slightly soluble in hot water and dilute acetic acid, insoluble in chloroform and ether. Derived from the fruit of Solanum aviculare Forst., a plant of the Solanaceae family.

Uses

α-Solasonine is a natural glycoalkaloid compound which has been shown to inhibit Gli-mediated transcritional activity.

Definition

ChEBI: Solasonine is an azaspiro compound, an oxaspiro compound and a steroid.

Purification Methods

Solasonine crystallises from aqueous 80% dioxane or MeOH in needles. [Bell & Briggs J Chem Soc 1 1942, Briggs et al. J Chem Soc 4645 1961, Briggs et al. J Chem Soc 2848 1963.] The picrate crystallises from 30% aqueous EtOH with m 197-198o(dec) [Briggs & Cambie J Chem Soc 1422 1958]. [Beilstein 27 III/IV 2006.]

References

Oddo et a/., Gazzetta, 35, 27 (1905)
Levi., J. Soc. Chem. Ind., 49, 395T (1930)
Briggs., Nature, 144, 247 (1939)
Briggs.,J. Chem. Soc., 3 (1942)
Briggs, Vining., ibid, 2809 (1953)
Hayes, Scaforth., ibid, 74S (1963)

SOLASONINE Preparation Products And Raw materials

Raw materials

Preparation Products

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SOLASONINE Suppliers

China 213 Germany 1 India 3 United Kingdom 7 United States 21 USA 1 Global 246
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
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58
Carbosynth
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--
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Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
MOLEKULA Ltd.
Tel
--
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Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
Apin Chemicals Limited (UK)
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--
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Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
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ETA SCIENTIFIC Co.,Ltd
Tel
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Email
sales@etascientific.com
Country
United Kingdom
ProdList
6090
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34
Apin Chemicals Ltd.
Tel
--
Fax
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Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
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42
Sequoia Research Products Ltd.
Tel
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Email
sales@seqchem.com
Country
United Kingdom
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3113
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View Lastest Price from SOLASONINE manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
SOLASONINE 19121-58-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-24
Shanghai Standard Technology Co., Ltd.
Product
Solasonine 19121-58-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-11-22
NanJing Spring & Autumn Biological Engineering CO., LTD.
Product
Solasonine 19121-58-5 19121-58-5
Price
US $52.00/mg
Min. Order
20mg
Purity
≥98%
Supply Ability
1000.00 kgs
Release date
2019-07-18

19121-58-5, SOLASONINERelated Search:

Solamargine SOLASODINE Monomelittoside Gypenoside L Angoroside C (2R)-2,3-Dihydroxypropyl-b-D-galactopyranoside D-Galactose 2-(2-DODECYLOXYETHOXY)ETHANOL 2-(HEXADECYLOXY)ETHANOL SEC-BUTYL ETHER 12-AMINO-1-DODECANOL 1,1,2-TRIETHOXYETHANE Cyclopentamine CHOLESTERYL ETHYL ETHER Dipropylene glycol monomethyl ether Citronellol 2-(DODECYLOXY)ETHANOL Cholesterol

  • Solasonine alpha-Solasonine
  • NSC 82149
  • PURAPURIN
  • PURAPURINE
  • SOLANINE S
  • SOLANCARPIN
  • Solasonine 19121-58-5
  • SOLASODAMINE
  • SOLASONIN
  • SOLASONINE
  • 5-SOLASODEN-3BETA-OL 3-O-6-D-DEOXY-ALPHA-L-MONOPYRANOSYL (1->2)-BETA-D-GLUCOPYRANOSYL (1->3)-BETA-D-GALACTOPYRANOSIDE
  • .beta.-D-Galactopyranoside, (3.beta.,22.alpha.,25R)-spirosol-5-en-3-yl O-6-deoxy-.alpha.-L-mannopyranosyl-(1?2)-O-.beta.-D-glucopyranosyl-(1?3)-
  • SOLASONINE(RG)
  • [(22R,25R)-Spirosol-5-en-3β-yl]2-O-(6-deoxy-α-L-mannopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-galactopyranoside
  • Solasoonine
  • ALPHA-SOLASONINE
  • β-D-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-
  • α-Solasonine
  • (2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-(((2'S,4S,5'R,6aR,6bS,8aS,8bR,9S,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Solasonine extrapure, 98%
  • Solasonine (6CI, 7CI, 8CI)
  • (2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-Hydroxy-2-(hydroxymethyl)-6-(((4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • α-Solasonine-RM
  • (2S,3R,4S,5S,6R)-2-(((2R,3S,4S,5R,6R)-3-Hydroxy-2-(hydroxymethyl)-6-(((4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,4,5,6,6a,6b,7,8,8a,8b,9,11a,12,12a,12b-hexadecahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-piperidin]-4-yl)oxy)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • 19121-58-5
  • C45H73NO16
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Alkaloids