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4-Aminothiophenol

Product Name
4-Aminothiophenol
CAS No.
1193-02-8
Chemical Name
4-Aminothiophenol
Synonyms
4-AMINOBENZENETHIOL;P-AMINOTHIOPHENOL;4-Aminothiopheno;4-MERCAPTOANILINE;P-AMINOBENZENETHIOL;4-Aminothophenol;4-AMINOTHIOPHENOL;p-Mercaptoaniline;p-Aminophenylthiol;p-amino-benzenethio
CBNumber
CB3289884
Molecular Formula
C6H7NS
Formula Weight
125.19
MOL File
1193-02-8.mol
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4-Aminothiophenol Property

Melting point:
37-42 °C(lit.)
Boiling point:
140-145 °C16 mm Hg(lit.)
Density 
1.136 (estimate)
refractive index 
1.4606 (estimate)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
7.3g/l
pka
8.74±0.10(Predicted)
form 
Crystals, Flakes or Crystalline Mass
color 
Off-white to brown
Water Solubility 
Immiscible with water.
Sensitive 
Stench
BRN 
906904
CAS DataBase Reference
1193-02-8(CAS DataBase Reference)
NIST Chemistry Reference
4-Aminothiophenol(1193-02-8)
EPA Substance Registry System
4-Aminothiophenol (1193-02-8)
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Safety

Hazard Codes 
C
Risk Statements 
34-37
Safety Statements 
26-28-36/37/39-45-25-27
RIDADR 
UN 3263 8/PG 2
WGK Germany 
3
RTECS 
DC0602500
10-13-23
Hazard Note 
Corrosive/Stench
HazardClass 
8
PackingGroup 
III
HS Code 
29309070
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
422967
Product name
4-Aminothiophenol
Purity
97%
Packaging
5g
Price
$56.7
Updated
2024/03/01
Sigma-Aldrich
Product number
422967
Product name
4-Aminothiophenol
Purity
97%
Packaging
25g
Price
$135
Updated
2024/03/01
TCI Chemical
Product number
A0623
Product name
4-Aminobenzenethiol
Purity
>98.0%(GC)
Packaging
5g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
A0623
Product name
4-Aminobenzenethiol
Purity
>98.0%(GC)
Packaging
25g
Price
$107
Updated
2024/03/01
Alfa Aesar
Product number
A14082
Product name
4-Aminothiophenol, 97%
Packaging
5g
Price
$57.3
Updated
2024/03/01
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4-Aminothiophenol Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline low melting mass

Uses

4-Aminothiophenol is used in the synthesis of pectin-4-aminothiophenol conjugates and it forms self-assembled monolayers (SAMs) in the development of DNA. It is used in the detection of thrombin by protein recognition using surface-enhanced Raman spectroscopy (SERS), which finds applications in silver and gold nano particles. It acts as a linker to thiol (SH) functionalizes multiwalled carbon nanotubes (MWCNTs).

Uses

4-Aminothiophenol (4-ATP) was employed as bifunctional molecule to functionalize gold nanoparticles (NPs) used in surface-enhanced Raman spectroscopy (SERS) detection of thrombin by protein recognition.

Preparation

synthesis of 4-aminothiophenol: A mixture of 128 g. of p-chloronitrobenzene and a solution of 480 g. of sodium sulfide nonahydrate in 2 l. of water is heated to reflux for 8 hours. The cooled mixture is extracted with ether to remove a small amount of oil, the remaining aqueous solution is saturated with sodium chloride, and 240 g. of glacial acetic acid is added. The precipitated oil is removed by ether extraction, and the resulting ethereal solution is dried over sodium sulfate and distilled to give 70 g. (69%) of 4-aminothiophenol boiling at 143-146°/17 mm. and melting at 43-45°.

General Description

4-Aminothiophenol (p-aminothiophenol, PATP) is an aromatic thiol. The self-assembly of silver and gold nano particles which are interconnected with 4-ATP to form metal-molecule-metal sandwich architecture has been characterized by surface enhanced Raman scattering (SERS) using an off-surface plasmon resonance condition. Chemical transformation of PATP to 4,4-dimercaptoazobenzene (DMAB) has been extensively studied.

4-Aminothiophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Aminothiophenol Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
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View Lastest Price from 4-Aminothiophenol manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
4-Aminothiophenol 1193-02-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2023-03-31
Hebei Zhanyao Biotechnology Co. Ltd
Product
4-Aminothiophenol 1193-02-8
Price
US $10.00/KG
Min. Order
1g
Purity
99%
Supply Ability
20 tons
Release date
2021-09-07
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Aminothiophenol 1193-02-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

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