ChemicalBook > CAS DataBase List > N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester

N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester

Product Name
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
CAS No.
286961-14-6
Chemical Name
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
Synonyms
tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate;N-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester;EOS-60794;3,6-DIHYDR;PyridineC5H5N;N-BOC-1.2.5.6;N-BOC-1.2.5.8-;tert-butyl 4-(4;1-Boc-1,2,5,6-tetrahydrop...;6-tetrahydropyridine-1-carboxylate
CBNumber
CB3290758
Molecular Formula
C16H28BNO4
Formula Weight
309.21
MOL File
286961-14-6.mol
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N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Property

Melting point:
114.0 to 118.0 °C
Boiling point:
348.0±52.0 °C(Predicted)
Density 
1.05±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Sparingly), Dichloromethane (Sparingly), DMSO (Slightly)
pka
-1.21±0.40(Predicted)
form 
Solid
color 
white to off-white
Water Solubility 
Soluble in most organic solvents. Insoluble in water.
InChI
InChI=1S/C16H28BNO4/c1-14(2,3)20-13(19)18-10-8-12(9-11-18)17-21-15(4,5)16(6,7)22-17/h8H,9-11H2,1-7H3
InChIKey
VVDCRJGWILREQH-UHFFFAOYSA-N
SMILES
C1N(C(OC(C)(C)C)=O)CC=C(B2OC(C)(C)C(C)(C)O2)C1
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37-60
WGK Germany 
3
TSCA 
No
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
706531
Product name
N-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester
Purity
95%
Packaging
1g
Price
$138
Updated
2024/03/01
TCI Chemical
Product number
B4051
Product name
1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$92
Updated
2024/03/01
Alfa Aesar
Product number
H66193
Product name
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%
Packaging
1g
Price
$66.65
Updated
2024/03/01
Alfa Aesar
Product number
H66193
Product name
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%
Packaging
5g
Price
$243.65
Updated
2024/03/01
Alfa Aesar
Product number
H66193
Product name
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester, 95%
Packaging
25g
Price
$1045
Updated
2024/03/01
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N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Chemical Properties,Usage,Production

Chemical Properties

off-white powder

Uses

Reagent used for suzuki-Miyaura cross-coupling using palladium phosphine catalyst, palladium-catalyzed ligand-controlled regioselective Suzuki coupling, wrenchnolol derivative optimized for gene activation in cells. Also used in Preparation of several enzymatic inhibitors and receptor ligands, orally active anaplastic lymphoma kinase inhibitors and oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes.

Uses

N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester is an intermediate for organic synthesis and pharmaceutical research and development, and can be used for suzuki reaction.

N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester Suppliers

Americas 1 Belgium 1 Canada 2 China 323 Europe 2 France 1 Germany 3 India 12 Japan 1 United Kingdom 4 United States 43 USA 1 Global 394
AllyChem Co., Ltd.
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Energy Chemical
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View Lastest Price from N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester manufacturers

Wuhan Han Sheng New Material Technology Co.，Ltd
Product
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester 286961-14-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50tons
Release date
2023-09-21
Henan Aochuang Chemical Co.,Ltd.
Product
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester 286961-14-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-22
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester 286961-14-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

286961-14-6, N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol esterRelated Search:

Pinacol Pyridine hydrobromide Propyleneglycol alginate Tris(trimethylsilyl)phosphate Methyl acrylate Pyridine Diethyl phthalate Pyridine hydrofluoride 1,1'-Carbonyldiimidazole Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Dimethyl succinate 2,2,4-Trimethyl-1,3-pentanediol monoisobutyrate Dihydromyrcenol tert-butyl 4-(4-amino-2-methoxyphenyl)piperazine-1-carboxylate tert-butyl 4-(4-hydroxybutyl)piperazine-1-carboxylate N-BOC-1,2,3,6-TETRAHYDROPYRIDINE N-BOC-3-Aminopiperidine N-Boc-4-iodopiperidine

  • N-BOC-1,2,5,6-TETRAHYDROPYRIDINE-4-(PINACOLATO)BORONATE
  • (N-TERT-BUTOXYCARBONYL)-1,2,3,6-TETRAHYDROPYRIDINE-4-BORONIC ACID PINACOL ESTER
  • 4-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 3,6-DIHYDRO-2H-PYRIDINE-1-TERT-BUTOXYCARBONYL-4-BORONIC ACID, PINACOL ESTER
  • 1-N-BOC-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE
  • 1-N-BOC-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H-PYRIDINE 98+%
  • N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
  • tert-butyl 1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine
  • tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate
  • 1-Boc-4-(4,4,5,5-tetraMethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine
  • tert-butyl 4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)- 1,2,3,6-tetrahydropyridine-1-carboxylate
  • PyridineC5H5N
  • 3,6-Dihydro-2H-pyridine-1-N-Boc-4-boronic acid pinacol ester
  • 4-(4,4,5,5-TetraMethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid isopropyl ester
  • 3,6-DIHYDR
  • tert-butyl4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate N-Boc-1,2,5,6-
  • 3,6-DIHYDRO-2H-PYRIDINE-1-TERT-BUTOXYCARBONYL-4-BORONIC ACID PINACOL ESTER; N-BOC-1,2,5,6-TETRAHYDROPYRIDINE-4-(PINACOLATO)BORONATE
  • tert-Butyl 1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-1-carboxylate, tert-Butyl 3,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-1-carboxylate
  • tert-butyl 4-(hydroxy((3-hydroxy-2,3-diMethylbutan-2-yl)oxy)boryl)-5,6-dihydropyridine-1(2H)-carboxylate
  • 1-n-boc-3,6-dihydro-2h-pyridine-4-boronic acid pinacol ester
  • (1-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester
  • (N-tert-Butoxycarbonyl-1,2,3,6-tetrahydropyridin-4-yl)boronic acid pinacol ester
  • (N-tert-Butoxycarbonyl-1,2,5,6-tetrahydropyridin-4-yl)boronic acid pinacol ester
  • N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester 3,6-Dihydro-2H-pyridine-1-tert-butoxycarbonyl-4-boronic acid pinacol ester
  • [1-Boc-1,2,3,6-tetrahydropyridine-4-yl]boronic acid pinacol ester
  • N-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacoL
  • 1-Boc-1,2,5,6-tetrahydropyridine-4-ylboronic acid picol ester
  • 1,2,3,6-Tetrahydropyridine-4-boronic acid, pinacol ester, N-BOC protected 95%
  • 1-Boc-3,6-Dihydro-2H-pyridine-4-boronic acid pinacol ester
  • 4-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)-3,6-DIHYDRO-2H
  • 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylicacidtert-butylester
  • 1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester
  • tert-butyl5,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-1(2H)-carbo
  • 3,6-Dihydro-2H-pyridine-1-tert-butoxycarbonyl-4-boronic acid
  • (N-Tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester ,97%
  • tert-butyl 5,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-1(2H)-carboxylate
  • 1-N-BOC-4-(4,4,5,5-TETRAMETHYL-2-YL)-3,6-DIHYDRO-2H-PYRIDINE
  • N-(tert-butoxycarbonyl)-3,6-dihydro-2H-pyridine-4-boronic acidpinacol ester, 97%
  • 1,2,3,6-Tetrahydropyridine-4-boronic acid, pinacol ester, N-BOC protected
  • 6-tetrahydropyridine-1-carboxylate
  • tert-butyl 4-(4
  • 3,6-Dihydro-2H-Pyridine-1-Boc -4-Boronic Acid Pinacol Ester
  • N-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester
  • tert-butyl 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylat
  • 1-Boc-1,2,5,6-tetrahydropyridine-4-boronic acid pinacol ester
  • 1-N-Boc-4-(4,4,5,5- tetraMethyl(1,3,2)dioxoborolan-2-yl)-3,6- dihydro-2H-pyridine
  • tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate, tert-Butyl 3,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-1(2H)-carboxylate
  • 1-Boc-1,2,5,6-tetrahydrop...
  • 1-(tert-Butoxycarbonyl)-1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • t-Butyl 4-(4,4,5,5,-tetramethyl-1,3,2,-dioxaborolan-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate
  • 1-N-BOC-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN
  • 4-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)-3,6-DIH
  • Pinacol 1-Boc-2,3,6-trihydropyridin-4-ylboronate
  • tert-butyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate
  • tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
  • [1-Boc-1,2,5,6-tetrahydropyridine-4-yl]boronic acid pinacol ester
  • N-BOC-1.2.5.6
  • N-BOC-1.2.5.8-