ChemicalBook > CAS DataBase List > 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT

8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT

Product Name
8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
CAS No.
142754-28-7
Chemical Name
8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
Synonyms
Sp-8-Cl-cAMPS;SP-8-CL-CAMPS, NA;SP-8-CL-CAMPS SODIUM SALT;8-chloroadenosine-3’,5’-cyclicmonophosphorothioate;ADENOSINE, 8-CHLORO-,CYCLIC 3',5'-[HYDROGEN (S)-P...;8-Chloroadenosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer;8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT;8-chloroadenosine-3’,5’-cyclicmonophosphorothioate,sp-isomer(sp-8-cl-camps);ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-CHLORO-, SP-ISOMER, SODIUM SALT
CBNumber
CB3298350
Molecular Formula
C10H10ClN5NaO5PS
Formula Weight
401.7
MOL File
142754-28-7.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
NUC0004584
Product name
8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
Purity
95.00%
Packaging
5MG
Price
$501.94
Updated
2021/12/16
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8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Chemical Properties,Usage,Production

Uses

Sp-8-Cl-cAMPS is an analog of cAMP (HY-B1511) and a derivative of Sp-8-Cl-cAMP. Sp-8-Cl-cAMPS inhibits the growth of human leukemia cell HL-60 and colon cancer cell LS-174T, with IC50 of 8-100 μM. Sp-8-Cl-cAMPS activates the protein kinases cAKI and cAKII, with Ka of 0.25 and 3.2 μM[1].

References

[1] Yokozaki H, et al., Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cells. Cancer Res. 1992 May 1;52(9):2504-8. PMID:1314695

8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Suppliers

China 3 Germany 1 United Kingdom 1 United States 4 Global 9
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142754-28-7, 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALTRelated Search:

ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE 8-CHLORO-2'-DEOXYADENOSINE Adenosinehydrochloride 8-CHLOROADENINE 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT 8-Chloroadenosine 2-CHLORO-1-ETHOXYMETHYLIMIDAZOLE

  • 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
  • ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-CHLORO-, SP-ISOMER, SODIUM SALT
  • SP-8-CL-CAMPS, NA
  • SP-8-CL-CAMPS SODIUM SALT
  • 8-chloroadenosine-3’,5’-cyclicmonophosphorothioate
  • 8-chloroadenosine-3’,5’-cyclicmonophosphorothioate,sp-isomer(sp-8-cl-camps)
  • 8-Chloroadenosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer
  • Sp-8-Cl-cAMPS
  • ADENOSINE, 8-CHLORO-,CYCLIC 3',5'-[HYDROGEN (S)-P...
  • 142754-28-7