ChemicalBook > CAS DataBase List > ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE

ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE

Product Name
ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE
CAS No.
71774-13-5
Chemical Name
ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE
Synonyms
cAMPS-Sp;(S)-Adenosine;Sp cAMPS,SpcAMPS;Rp cAMPS TEA salt;Rp-cAMPS TEA salt;Triethylammoniumsalt;camps,sp-isomer,teasalt;ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE;Adenosine, cyclic 3',5'-[hydrogen (S)-phosphorothioate];Adenosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer
CBNumber
CB5506390
Molecular Formula
C10H12N5O5PS
Formula Weight
345.27
MOL File
71774-13-5.mol
More
Less

ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Property

Boiling point:
648.0±65.0 °C(predicted)
Density 
2.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
storage temp. 
Desiccate at -20°C
pka
-0.55±0.60(predicted)
form 
crystalline solid
Water Solubility 
water: 20mg/mL
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
A280468
Product name
(S)-Adenosine,cyclic3'',5''-(hydrogenphosphorothioate)triethylammonium
Packaging
2.5mg
Price
$240
Updated
2021/12/16
TRC
Product number
A280468
Product name
(S)-Adenosine,cyclic3'',5''-(hydrogenphosphorothioate)triethylammonium
Packaging
1mg
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
NA08994
Product name
Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt
Packaging
1mg
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
NA08994
Product name
Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt
Packaging
2mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
NA08994
Product name
Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt
Packaging
5mg
Price
$450
Updated
2021/12/16
More
Less

ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Chemical Properties,Usage,Production

Uses

(S)-Adenosine, cyclic 3'',5''-(hydrogenphosphorothioate) triethylammonium is an activator of PKA.

Definition

ChEBI: (Sp)-cAMPS is a nucleoside 3',5'-cyclic phosphorothioate having adenine as the nucleobase (the Sp-stereoisomer). It has a role as a protein kinase agonist. It is a member of purines and a nucleoside 3',5'-cyclic phosphorothioate. It is functionally related to a 3',5'-cyclic AMP.

Biological Activity

Cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor.

in vivo

In chronic alcohol consumption (CAC) mice, direct infusion of the Sp-cAMPS (1 μg/μL) into the prefrontal cortex significantly improves or impairs, respectively, working memory performance in withdrawn and water animals[5].

IC 50

PKA I; PKA II; PDE3A: 47.6 μM (Ki); PDE10 GAF domain: 50 μM (EC50)

ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE Suppliers

China 9 Germany 2 United Kingdom 3 United States 8 Global 22
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
NewCan Biotech Limited
Tel
+86-0571-86912261 +8613735419629
Email
sales@newcanbio.com
Country
China
ProdList
9985
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
BOC Sciences
Tel
16314854226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
9713
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Enzo Biochem Inc
Tel
Enzo Biochem Inc. 13797054060
Email
Enzoname@qq.com
Country
China
ProdList
6174
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
Advantage
58

71774-13-5, ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATERelated Search:

ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-BROMO-, RP-ISOMER, SODIUM SALT ADENOSINE-2',3'-CYCLIC MONOPHOSPHOROTHIOATE, EXO/SP-ISOMER SODIUM SALT,ADENOSINE-2',3'-CYCLIC MONOPHOSPHOROTHIOATE, ENDO/RP-ISOMER SODIUM SALT ADENOSINE-2',3'-CYCLIC MONOPHOSPHOROTHIOATE, ENDO/RP-ISOMER SODIUM SALT,ADENOSINE-2',3'-CYCLIC MONOPHOSPHOROTHIOATE, EXO/SP-ISOMER SODIUM SALT ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER TRIETHYL AMMONIUM SALT 2'-(6-AMINOHEXYLCARBAMOYL)ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER, IMMOBILIZED ON AGAROSE GEL 2'-(6-AMINOHEXYLCARBAMOYL) ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER, IMMOBILIZED ON AGAROSE GEL sp-adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt hydrate,ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER TRIETHYL AMMONIUM SALT ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-CHLORO-, RP-ISOMER, SODIUM SALT ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER, TRIETHYLAMMONIUM SALT ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-PIPERIDINO-, RP-ISOMER, SODIUM SALT RP-ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT 8-(4-CHLOROPHENYLTHIO)ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT SP-ADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-BROMO-, SP-ISOMER, SODIUM SALT ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-PIPERIDINO-, SP-ISOMER, SODIUM SALT ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 2'-O-MONOBUTYRYL-, RP-ISOMER, SODIUM SALT ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, ACETOXYMETHYL ESTER, SP-ISOMER

  • adenosine-3’,5’-cyclicmonophosphorothioate,sp-isomer(sp-camps),sodiumsalt
  • camps,sp-isomer,teasalt
  • ADENOSINE-3',5'-CYCLIC -MONOPHOSPHOROTHIOATE
  • (S)-Adenosine
  • cAMPS-Sp
  • Triethylammoniumsalt
  • (S)-ADENOSINE, CYCLIC 3',5'-(HYDROGENPHOSPHOROTHIOATE) TRIETHYLAMMONIUM
  • ADENOSINE3,5-CYCLICMONOPHOSPHOTHIOATESP-ISOMERTRIETHYLAMMONIUMSALT,HIGHPURITY
  • Adenosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer
  • Adenosine, cyclic 3',5'-[hydrogen (S)-phosphorothioate]
  • Rp cAMPS TEA salt
  • Rp-cAMPS TEA salt
  • Sp cAMPS,SpcAMPS
  • 71774-13-5
  • C10H12N5O5PSC6H16N
  • Cyclic Nucleotide related