BC 11-38

Product Name: BC 11-38
CAS No.: 686770-80-9
Chemical Name: BC 11-38
Synonyms: 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one;3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one;Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)-;cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138
CBNumber: CB33037165
Molecular Formula: C15H16N2OS2
Formula Weight: 304.43
MOL File: 686770-80-9.mol

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BC 11-38 Property

storage temp.: RT
solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 14 mg/ml with warming).
form: solid
color: White
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20167
Product name: BC-11-38
Purity: ≥98%
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 20167
Product name: BC-11-38
Purity: ≥98%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 20167
Product name: BC-11-38
Purity: ≥98%
Packaging: 25mg
Price: $252
Updated: 2024/03/01

TRC

Product number: B129345
Product name: BC11-38
Packaging: 25mg
Price: $285
Updated: 2021/12/16

ApexBio Technology

Product number: B7673
Product name: BC11-38
Packaging: 10mg
Price: $291
Updated: 2021/12/16

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BC 11-38 Chemical Properties,Usage,Production

Description

BC-11-38 (686770-80-9) is a? potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1? IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2

Uses

BC 11-38 is a selective inhibitor of phosphodiesterase 11. Potent PDE-11 inhibitor

References

1) Ceyhan et al. (2012), Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen; Chem. Biol., 19 155 2) Lu and Sewer (2015), p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation; Mol. Cell. Biol. 35 1223

BC 11-38 Preparation Products And Raw materials

Raw materials

Preparation Products

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BC 11-38 Suppliers

China 17 United Kingdom 2 United States 8 USA 1 Global 28

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
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Shanghai EFE Biological Technology Co., Ltd.

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Amadis Chemical Company Limited

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Lynnchem

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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MedBioPharmaceutical Technology Inc

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Energy Chemical

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Changzhou Furuisi Biotechnology Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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Bide Pharmatech Ltd.

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Kaifeng Mingren Pharmaceutical Co.,LTD

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Nantong QuanYi Biotechnology Co., Ltd

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Nanjing Shizhou Biology Technology Co.,Ltd

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RD International Technology Co., Limited

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Shanghai Hao Zhun Biological Technology Co., Ltd.

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686770-80-9, BC 11-38Related Search:

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3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one

6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one

Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)-

cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138

686770-80-9