ChemicalBook > CAS DataBase List > BC 11-38
BC 11-38
- Product Name
- BC 11-38
- CAS No.
- 686770-80-9
- Chemical Name
- BC 11-38
- Synonyms
- 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one;3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one;Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)-;cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138
- CBNumber
- CB33037165
- Molecular Formula
- C15H16N2OS2
- Formula Weight
- 304.43
- MOL File
- 686770-80-9.mol
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BC 11-38 Property
- storage temp.
- RT
- solubility
- Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 14 mg/ml with warming).
- form
- solid
- color
- White
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 20167
- Product name
- BC-11-38
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20167
- Product name
- BC-11-38
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20167
- Product name
- BC-11-38
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $252
- Updated
- 2024/03/01
TRC
- Product number
- B129345
- Product name
- BC11-38
- Packaging
- 25mg
- Price
- $285
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7673
- Product name
- BC11-38
- Packaging
- 10mg
- Price
- $291
- Updated
- 2021/12/16
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BC 11-38 Chemical Properties,Usage,Production
Description
BC-11-38 (686770-80-9) is a? potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1? IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2
Uses
BC 11-38 is a selective inhibitor of phosphodiesterase 11. Potent PDE-11 inhibitor
References
1) Ceyhan et al. (2012), Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen; Chem. Biol., 19 155 2) Lu and Sewer (2015), p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation; Mol. Cell. Biol. 35 1223
BC 11-38 Preparation Products And Raw materials
Raw materials
Preparation Products
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