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4'-Hydroxy-2,4-dimethoxychalcone

Product Name
4'-Hydroxy-2,4-dimethoxychalcone
CAS No.
151135-64-7
Chemical Name
4'-Hydroxy-2,4-dimethoxychalcone
Synonyms
4-O-Methylechinatin;4'-Hydroxy-2,dimethoxychalcone;4'-Hydroxy-2,4-dimethoxychalcone;4''-Hydroxy-2,4-dimethoxychalcone;4''-Hydroxy-2,4-dimethoxychalcone, 10 mM in DMSO;(E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one;(2E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one;2-Propen-1-one, 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-
CBNumber
CB33054362
Molecular Formula
C17H16O4
Formula Weight
284.31
MOL File
151135-64-7.mol
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4'-Hydroxy-2,4-dimethoxychalcone Property

form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN91163
Product name
4'-Hydroxy-2,4-dimethoxychalcone
Packaging
10mg
Price
$338
Updated
2021/12/16
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4'-Hydroxy-2,4-dimethoxychalcone Chemical Properties,Usage,Production

Uses

4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2].

in vivo

4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T1/2 of 1.94 hours, a Cmax of 158 ng/mL and an AUC of 384 ng?h/mL in four- to five-week-old ICR mice[1].

IC 50

Plasmodium

References

[1] Clare E Gutteridge, et al. In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones. Pharmacology. 2011;87(1-2):96-104. DOI:10.1159/000322532
[2] Qing-An Zheng, et al. Flavonoids from the Resin of Dracaena cochinchinensis. Helvetica Chimica Acta, 87(5), 1167–1171.

4'-Hydroxy-2,4-dimethoxychalcone Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-Hydroxy-2,4-dimethoxychalcone Suppliers

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BioBioPha Co., Ltd.
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Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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  • 4'-Hydroxy-2,4-dimethoxychalcone
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  • 4-O-Methylechinatin
  • (E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
  • (2E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one
  • 4''-Hydroxy-2,4-dimethoxychalcone
  • 4''-Hydroxy-2,4-dimethoxychalcone, 10 mM in DMSO
  • 4'-Hydroxy-2,dimethoxychalcone
  • 151135-64-7