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Bromo-PEG2-phosphonic acid ethyl ester

Product Name
Bromo-PEG2-phosphonic acid ethyl ester
CAS No.
1226767-94-7
Chemical Name
Bromo-PEG2-phosphonic acid ethyl ester
Synonyms
Bromo-PEG2-phosphonic acid ethyl ester;Bromo-PEG2-phosphonic acid diethyl ester;Diethyl [2-[2-(2-Bromoethoxy)ethoxy]ethyl]phosphonate;Diethyl P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]phosphonate;Phosphonic acid, P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-, diethyl ester
CBNumber
CB33062442
Molecular Formula
C10H22BrO5P
Formula Weight
333.16
MOL File
1226767-94-7.mol
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Bromo-PEG2-phosphonic acid ethyl ester Property

Boiling point:
387.4±27.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B680840
Product name
Bromo-PEG2-phosphonicAcidEthylEster
Packaging
10mg
Price
$90
Updated
2021/12/16
BroadPharm
Product number
BP-21708
Product name
Bromo-PEG2-phosphonicaciddiethylester
Purity
98%
Packaging
100mg
Price
$260
Updated
2021/12/16
BroadPharm
Product number
BP-21708
Product name
Bromo-PEG2-phosphonicaciddiethylester
Purity
98%
Packaging
250mg
Price
$430
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002410
Product name
BROMO-PEG2-PHOSPHONIC ACID ETHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$505.59
Updated
2021/12/16
Apolloscientific
Product number
BIPG1344
Product name
Bromo-PEG2-phosphonic acid ethyl ester
Packaging
100mg
Price
$507
Updated
2021/12/16
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Bromo-PEG2-phosphonic acid ethyl ester Chemical Properties,Usage,Production

Description

Bromo-PEG2-phosphonic acid diethyl ester is a PEG linker containing a bromine group and a phosphonic acid diethyl ester. The bromine group is a good leaving group and participates in substitution reactions. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous media.

Uses

Bromo-PEG2-phosphonic acid diethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromo-PEG2-phosphonic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromo-PEG2-phosphonic acid ethyl ester Suppliers

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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1226767-94-7, Bromo-PEG2-phosphonic acid ethyl esterRelated Search:


  • Bromo-PEG2-phosphonic acid ethyl ester
  • Bromo-PEG2-phosphonic acid diethyl ester
  • Phosphonic acid, P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]-, diethyl ester
  • Diethyl P-[2-[2-(2-bromoethoxy)ethoxy]ethyl]phosphonate
  • Diethyl [2-[2-(2-Bromoethoxy)ethoxy]ethyl]phosphonate
  • 1226767-94-7