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Thio-PEG2-t-butyl ester

Product Name
Thio-PEG2-t-butyl ester
CAS No.
1398044-50-2
Chemical Name
Thio-PEG2-t-butyl ester
Synonyms
HS-PEG2-COOtBu;HS-PEG2-CH2CH2COOtBu;SH-PEG2-CH2CH2COOtBu;Thio-PEG2-t-butyl ester;Thiol-PEG2-t-butly ester;Thiol-PEG2-t-butyl ester;Thiol-PEG3-t-butly ester;tert-butyl 3-[2-(2-sulfanylethoxy)ethoxy]propanoate;tert-Butyl 3-[2-(2-mercaptoethoxy)ethoxy]propanoate;Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-, 1,1-dimethylethyl ester
CBNumber
CB33062679
Molecular Formula
C11H22O4S
Formula Weight
250.35
MOL File
1398044-50-2.mol
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Thio-PEG2-t-butyl ester Property

Boiling point:
330.6±27.0 °C(Predicted)
Density 
1.041±0.06 g/cm3(Predicted)
pka
9?+-.0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T351223
Product name
Thiol-PEG2-t-butylEster
Packaging
5mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
BIPG1847
Product name
Thio-PEG2-t-butyl ester
Packaging
100mg
Price
$428
Updated
2021/12/16
purepeg
Product number
437802
Product name
HS-PEG2-CH2CH2COOtBu
Purity
min.95%
Packaging
1g
Price
$300
Updated
2021/12/16
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Thio-PEG2-t-butyl ester Chemical Properties,Usage,Production

Biological Activity

Thiol-PEG2-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Thio-PEG2-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Thio-PEG2-t-butyl ester Suppliers

Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from Thio-PEG2-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Thiol-PEG2-t-butyl ester 1398044-50-2
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-27

1398044-50-2, Thio-PEG2-t-butyl esterRelated Search:


  • HS-PEG2-COOtBu
  • HS-PEG2-CH2CH2COOtBu
  • Thio-PEG2-t-butyl ester
  • Thiol-PEG2-t-butyl ester
  • Thiol-PEG2-t-butly ester
  • SH-PEG2-CH2CH2COOtBu
  • Thiol-PEG3-t-butly ester
  • Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-, 1,1-dimethylethyl ester
  • tert-Butyl 3-[2-(2-mercaptoethoxy)ethoxy]propanoate
  • tert-butyl 3-[2-(2-sulfanylethoxy)ethoxy]propanoate
  • 1398044-50-2
  • peg