ChemicalBook > CAS DataBase List > 2,4,5-Tribromoimidazole

2,4,5-Tribromoimidazole

Application

Product Name: 2,4,5-Tribromoimidazole
CAS No.: 2034-22-2
Chemical Name: 2,4,5-Tribromoimidazole
Synonyms: TIMTEC-BB SBB001252;2,4,5-tribromoimidazo;2,4,5-tribromo-imidazol;2,4,5-TRIBROMOIMIDAZOLE;2,4,5-Tribromoimidazole,97%;2,4,5-TRIBROMO-1H-IMIDAZOLE;1H-Imidazole, 2,4,5-tribromo-;2,4,5-Tribromoimidazole，98%min;2,4,5- threebroMinatediMidazole;2,4,5-TribroMoiMidazole, 97% 5GR
CBNumber: CB3311987
Molecular Formula: C3HBr3N2
Formula Weight: 304.77
MOL File: 2034-22-2.mol

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2,4,5-Tribromoimidazole Property

Melting point:: 217-220 °C (dec.) (lit.)
Boiling point:: 401.3±48.0 °C(Predicted)
Density: 3.8211 (rough estimate)
refractive index: 1.6500 (estimate)
storage temp.: 2-8°C
form: Powder
pka: 6.32±0.10(Predicted)
color: Beige-yellow
BRN: 115314
InChIKey: JCGGPCDDFXIVQB-UHFFFAOYSA-N
CAS DataBase Reference: 2034-22-2(CAS DataBase Reference)
NIST Chemistry Reference: Imidazole, 2,4,5-tribromo-(2034-22-2)

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Safety

Hazard Codes: T,Xi
Risk Statements: 23/24/25-36/37/38-25
Safety Statements: 22-26-36/37/39-45
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: NI8660000
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: II
HS Code: 29332990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 141704
Product name: 2,4,5-Tribromoimidazole
Purity: 97%
Packaging: 25g
Price: $41.3
Updated: 2025/07/31

TCI Chemical

Product number: T2266
Product name: 2,4,5-Tribromoimidazole
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $39
Updated: 2025/07/31

TCI Chemical

Product number: T2266
Product name: 2,4,5-Tribromoimidazole
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $110
Updated: 2025/07/31

TRC

Product number: T772633
Product name: 2,4,5-Tribromoimidazole
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: T772633
Product name: 2,4,5-Tribromoimidazole
Packaging: 50mg
Price: $45
Updated: 2021/12/16

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2,4,5-Tribromoimidazole Chemical Properties,Usage,Production

Application

2,4,5-Tribromoimidazole is an organic intermediate that can be obtained by brominating imidazole. 2,4,5-Tribromoimidazole can be debrominated to give 4,5-dibromoimidazole.

Chemical Properties

BEIGE-YELLOW POWDER

General Description

2,4,5-Tribromoimidazole(2,4,5-TBI) on condensation with sugar precursors yields 2,4,5-TBI nucleosides.

Biochem/physiol Actions

2,4,5-Tribromoimidazole induces poisoning typical of uncouplers of oxidative phosphorylation in rats.

Synthesis

288-32-4

2034-22-2

The general procedure for the synthesis of 2,4,5-tribromoimidazole from imidazole was as follows: to a three-necked flask equipped with a thermostatic separatory funnel was added imidazole (29.24 g, 0.43 mol), sodium acetate (317.34 g, 3.87 mol) and acetic acid (150 mL). The mixture was dissolved in additional acetic acid (100 mL). Bromine (65 mL, 1.28 mol) was added slowly dropwise through a thermostatic separatory funnel at room temperature, controlling the reaction temperature to not exceed 40°C. After the dropwise addition was completed, the reaction mixture continued to be stirred for 3 hours at room temperature. Upon completion of the reaction, the reaction solution was poured into 1.5 L of water to induce precipitation of the solid product. The solid product was collected by filtration and washed several times with water to remove impurities. Finally, the solid product was dried to afford the target compound 2,4,5-tribromoimidazole (120 g, 92% yield).

References

[1] Patent: CN106256830, 2016, A. Location in patent: Paragraph 0044; 0049; 0050; 0051
[2] Tetrahedron Letters, 2015, vol. 56, # 41, p. 5646 - 5650
[3] Tetrahedron Letters, 1998, vol. 39, # 44, p. 8163 - 8166
[4] Tetrahedron, 1999, vol. 55, # 4, p. 935 - 942
[5] Journal of Organic Chemistry, 1992, vol. 57, # 9, p. 2740 - 2741

2,4,5-Tribromoimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,4,5-Tribromoimidazole manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2,4,5-Tribromoimidazole 2034-22-2
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

Career Henan Chemical Co

Product: 2,4,5-Tribromoimidazole 2034-22-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-14

2034-22-2, 2,4,5-TribromoimidazoleRelated Search:

Bromotrimethylsilane N-(Trimethylsilyl)imidazole Imidazole Phosphorus oxybromide 2,2,2-Tribromoethanol 2,4,5-TRIBROMO-1-METHYL-1H-IMIDAZOLE 1-BENZYL-2,4,5-TRIBROMO-1H-IMIDAZOLE ETHYL 2-(2,4,5-TRIBROMO-1H-IMIDAZOL-1-YL)ACETATE 2,4,5-TRIBROMO-1-(METHOXYMETHYL)-1H-IMIDAZOLE 2,4,5-Tribromoimidazole 1-Methyl-tribromoimidazole 2,4,5-tribromoimidazole-1-n-butylcarboxylate N'1-BENZYLIDENE-2-(2,4,5-TRIBROMO-1H-IMIDAZOL-1-YL)ETHANOHYDRAZIDE 1-Dimethylcarbamoyl-2,4,5-tribromoimidazole,2,4,5-tribromoimidazole-1-dimethylcarbamic acid 2,4,5-TRIBROMO-1-(2-METHOXYETHYL)-1H-IMIDAZOLE 2,4,5-TRIBROMO-1-[2-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-ETHYL]-1H-IMIDAZOLE 2,4,5-TRIBROMO-1-VINYLIMIDAZOLE

1H-Imidazole, 2,4,5-tribromo-

2,4,5-tribromo-imidazol

TIMTEC-BB SBB001252

2,4,5-TRIBROMO-1H-IMIDAZOLE

2,4,5-TRIBROMOIMIDAZOLE

2,4,5-tribromoimidazo

2,4,5-Tribromoimidazole,97%

2,4,5-TribroMoiMidazole, 97% 25GR

2,4,5-TribroMoiMidazole, 97% 5GR

2,4,5- threebroMinatediMidazole

2,4,5-Tribromoimidazole, 10 mM in DMSO

2,4,5-Tribromoimidazole，98%min

2034-22-2

C3HBr3N2

Imidazoles

Halogenated Heterocycles

Heterocyclic Building Blocks

Building Blocks

alkyl bromide

Imidazol&Benzimidazole

Miscellaneous

Imidaxoles

Halogenated Heterocycles

Heterocyclic Building Blocks

ImidazolesBuilding Blocks

blocks

Bromides

Imidazoles