2,4,5-Tribromoimidazole
Application- Product Name
- 2,4,5-Tribromoimidazole
- CAS No.
- 2034-22-2
- Chemical Name
- 2,4,5-Tribromoimidazole
- Synonyms
- TIMTEC-BB SBB001252;2,4,5-tribromoimidazo;2,4,5-tribromo-imidazol;2,4,5-TRIBROMOIMIDAZOLE;2,4,5-Tribromoimidazole,97%;2,4,5-TRIBROMO-1H-IMIDAZOLE;1H-Imidazole, 2,4,5-tribromo-;2,4,5-Tribromoimidazole，98%min;2,4,5- threebroMinatediMidazole;2,4,5-TribroMoiMidazole, 97% 5GR
- CBNumber
- CB3311987
- Molecular Formula
- C3HBr3N2
- Formula Weight
- 304.77
- MOL File
- 2034-22-2.mol
2,4,5-Tribromoimidazole Property
- Melting point:
- 217-220 °C (dec.) (lit.)
- Boiling point:
- 401.3±48.0 °C(Predicted)
- Density
- 3.8211 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- 2-8°C
- form
- Powder
- pka
- 6.32±0.10(Predicted)
- color
- Beige-yellow
- BRN
- 115314
- InChIKey
- JCGGPCDDFXIVQB-UHFFFAOYSA-N
- CAS DataBase Reference
- 2034-22-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Imidazole, 2,4,5-tribromo-(2034-22-2)
Safety
- Hazard Codes
- T,Xi
- Risk Statements
- 23/24/25-36/37/38-25
- Safety Statements
- 22-26-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- NI8660000
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29332990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 141704
- Product name
- 2,4,5-Tribromoimidazole
- Purity
- 97%
- Packaging
- 25g
- Price
- $41.3
- Updated
- 2025/07/31
- Product number
- T2266
- Product name
- 2,4,5-Tribromoimidazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- T2266
- Product name
- 2,4,5-Tribromoimidazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $110
- Updated
- 2025/07/31
- Product number
- T772633
- Product name
- 2,4,5-Tribromoimidazole
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- T772633
- Product name
- 2,4,5-Tribromoimidazole
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
2,4,5-Tribromoimidazole Chemical Properties,Usage,Production
Application
2,4,5-Tribromoimidazole is an organic intermediate that can be obtained by brominating imidazole. 2,4,5-Tribromoimidazole can be debrominated to give 4,5-dibromoimidazole.
Chemical Properties
BEIGE-YELLOW POWDER
General Description
2,4,5-Tribromoimidazole(2,4,5-TBI) on condensation with sugar precursors yields 2,4,5-TBI nucleosides.
Biochem/physiol Actions
2,4,5-Tribromoimidazole induces poisoning typical of uncouplers of oxidative phosphorylation in rats.
Synthesis
288-32-4
2034-22-2
The general procedure for the synthesis of 2,4,5-tribromoimidazole from imidazole was as follows: to a three-necked flask equipped with a thermostatic separatory funnel was added imidazole (29.24 g, 0.43 mol), sodium acetate (317.34 g, 3.87 mol) and acetic acid (150 mL). The mixture was dissolved in additional acetic acid (100 mL). Bromine (65 mL, 1.28 mol) was added slowly dropwise through a thermostatic separatory funnel at room temperature, controlling the reaction temperature to not exceed 40°C. After the dropwise addition was completed, the reaction mixture continued to be stirred for 3 hours at room temperature. Upon completion of the reaction, the reaction solution was poured into 1.5 L of water to induce precipitation of the solid product. The solid product was collected by filtration and washed several times with water to remove impurities. Finally, the solid product was dried to afford the target compound 2,4,5-tribromoimidazole (120 g, 92% yield).
References
[1] Patent: CN106256830, 2016, A. Location in patent: Paragraph 0044; 0049; 0050; 0051
[2] Tetrahedron Letters, 2015, vol. 56, # 41, p. 5646 - 5650
[3] Tetrahedron Letters, 1998, vol. 39, # 44, p. 8163 - 8166
[4] Tetrahedron, 1999, vol. 55, # 4, p. 935 - 942
[5] Journal of Organic Chemistry, 1992, vol. 57, # 9, p. 2740 - 2741
2,4,5-Tribromoimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
2,4,5-Tribromoimidazole Suppliers
- Tel
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- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
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View Lastest Price from 2,4,5-Tribromoimidazole manufacturers
- Product
- 2,4,5-Tribromoimidazole 2034-22-2
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- 2,4,5-Tribromoimidazole 2034-22-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-14