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spacer 18 Phosphoramidite

Product Name
spacer 18 Phosphoramidite
CAS No.
125607-09-2
Chemical Name
spacer 18 Phosphoramidite
Synonyms
spacer 18 Phosphoramidite;DMT-PEG Phosphoramidite 18;Hexaethylene glycol phosphoramidite;Spacer 18(PEG)-DMT CE Phosphoramidite;1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite;Phosphoramidous acid, N,N-bis(1-methylethyl)-, 19,19-bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl ester;3-[2-[2-[2-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
CBNumber
CB33122454
Molecular Formula
C42H61N2O10P
Formula Weight
784.91
MOL File
125607-09-2.mol
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spacer 18 Phosphoramidite Property

Boiling point:
763.6±60.0 °C(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
good in most organic solvents
pka
3.53±0.70(Predicted)
form 
Liquid
color 
Colorless to light yellow
Appearance
colorlessoryellowish oil
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
B6709
Product name
1,1-Bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl 2-Cyanoethyl N,N-Diisopropylphosphoramidite
Packaging
500MG
Price
$150
Updated
2025/07/31
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spacer 18 Phosphoramidite Chemical Properties,Usage,Production

Description

Spacer phosphoramidite 18 (hexaethylene glycol phosphoramidite) is an amidite reagent for oligonucleotide synthesis. It provides a long hydrophilic linker that can be used for the synthesis of Scorpion-type qPCR probes, for spacing biotin from oligo strand, and for other applications requiring spatial separation of modifier and oligo

Uses

Hexaethylene glycol phosphoramidite (Spacer Phosphoramidite 18) is an amidite reagent for oligonucleotide synthesis. Hexaethylene glycol phosphoramidite can be used as a linker in synthesis of nucleotide chain and qPCR probes[1][2].

References

[1] Longcheng Li, Moorim KANG. Multi-valent oligonucleotide agent and methods of use thereof. WO2022166849A1
[2] Schaudy E, Lietard J, Somoza MM. Sequence Preference and Initiator Promiscuity for De Novo DNA Synthesis by Terminal Deoxynucleotidyl Transferase. ACS Synth Biol. 2021 Jul 16;10(7):1750-1760. DOI:10.1021/acssynbio.1c00142

spacer 18 Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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spacer 18 Phosphoramidite Suppliers

Hongene Biotech Corporation
Tel
021-64757213
Fax
86-21-64700613
Email
info@hongene.com
Country
China
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Suzhou GenePharma Co., Ltd.
Tel
+86 512 86668828 ,8026
Fax
+86 512 86668828
Email
chem@genepharma.com
Country
China
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46
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Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
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Wellman Pharmaceutical Group Limited
Tel
027-027-83778875 15807197853
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3931
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Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
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945717149@qq.com
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China
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8593
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Wuhu Huaren Science and Technology Co., Ltd.
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0553-5842013-801 18155347026
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jinhuaren@huarensh.com
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China
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Jinan Carbotang Biotech Co.,Ltd.
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+8615866703830
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China
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BOC Sciences
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1-631-614-7828
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United States
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Hefei Stongbio Co.,Ltd.
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15555170917
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Jiangsu Synthgene Biotechnology Co.,Ltd.
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starre@syngenebio.com
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125607-09-2, spacer 18 PhosphoramiditeRelated Search:


  • spacer 18 Phosphoramidite
  • Spacer 18(PEG)-DMT CE Phosphoramidite
  • Phosphoramidous acid, N,N-bis(1-methylethyl)-, 19,19-bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl ester
  • Hexaethylene glycol phosphoramidite
  • 1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite
  • DMT-PEG Phosphoramidite 18
  • 3-[2-[2-[2-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
  • 125607-09-2
  • C42H61N2O10P
  • Phosphoramidite