ChemicalBook > CAS DataBase List > (E)-1,4-Dibromobut-2-ene

(E)-1,4-Dibromobut-2-ene

Product Name
(E)-1,4-Dibromobut-2-ene
CAS No.
821-06-7
Chemical Name
(E)-1,4-Dibromobut-2-ene
Synonyms
trans-1,4-Dibromo-2-butene;Dibromobutene;4-DibroMo-2-butene;1,4-Dibromo-1-butene;(E)-1,4-Dibromobut-2;1,4-DIBROMO-2-PENTENE;4-dibromo-(e)-2-buten; 1,4-dibromo-, trans-;1,4-Dibromo-2-butene, E;4-dibromo-trans-2-buten
CBNumber
CB3312702
Molecular Formula
C4H6Br2
Formula Weight
213.9
MOL File
821-06-7.mol
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(E)-1,4-Dibromobut-2-ene Property

Melting point:
48-51 °C(lit.)
Boiling point:
205 °C(lit.)
Density 
1.9393 (estimate)
refractive index 
1.5361 (estimate)
Flash point:
113°C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystals or Crystalline Powder
color 
colorless to slightly brown
Water Solubility 
slightly soluble
BRN 
1719696
Stability:
Light Sensitive
InChIKey
RMXLHIUHKIVPAB-OWOJBTEDSA-N
CAS DataBase Reference
821-06-7(CAS DataBase Reference)
NIST Chemistry Reference
2-Butene, 1,4-dibromo-, (E)-(821-06-7)
EPA Substance Registry System
2-Butene, 1,4-dibromo-, (2E)- (821-06-7)
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Safety

Hazard Codes 
T,C
Risk Statements 
25-34-23/25
Safety Statements 
26-36/37/39-45-28A
RIDADR 
UN 2923 8/PG 2
WGK Germany 
2
RTECS 
EM4725000
F 
8-19
Hazard Note 
Toxic/Corrosive
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29033990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D39207
Product name
trans-1,4-Dibromo-2-butene
Purity
99%
Packaging
25g
Price
$101
Updated
2025/07/31
Sigma-Aldrich
Product number
D39207
Product name
trans-1,4-Dibromo-2-butene
Purity
99%
Packaging
100g
Price
$129
Updated
2025/07/31
TCI Chemical
Product number
D2944
Product name
trans-1,4-Dibromo-2-butene
Packaging
25G
Price
$86
Updated
2025/07/31
TCI Chemical
Product number
D2944
Product name
trans-1,4-Dibromo-2-butene
Packaging
250G
Price
$644
Updated
2025/07/31
TRC
Product number
D425545
Product name
(2E)-1,4-Dibromo-2-butene
Packaging
250g
Price
$410
Updated
2021/12/16
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(E)-1,4-Dibromobut-2-ene Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(2E)-1,4-Dibromo-2-butene, is used as a reagent in the preparation of diaminoalkenes though copper-mediated diamination reaction.

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 3324, 1971 DOI: 10.1021/jo00821a012

General Description

Crystals or white crystalline solid.

Air & Water Reactions

(E)-1,4-Dibromobut-2-ene may be sensitive to exposure to light and air. Insoluble in water.

Reactivity Profile

(E)-1,4-Dibromobut-2-ene is incompatible with strong oxidizers and strong bases.

Fire Hazard

(E)-1,4-Dibromobut-2-ene is probably combustible.

Synthesis

106-99-0

821-06-7

Example 1 (E)-1,4-dibromo-2-butene (A) Synthesis: 1,3-butadiene (60 mL, 0.70 mol) was added to a 500 mL round-bottomed flask and the flask was placed in a -78 °C cooling bath. Carbon tetrachloride (CCl4, 100 mL) pre-cooled to -20 °C was slowly added to the flask to ensure that the temperature of the reaction mixture was maintained below -20 °C. Subsequently, bromine was added dropwise over a period of 2 hours. The reaction mixture was stirred vigorously at room temperature for 14 hours. After completion of the reaction, most of the solvent was evaporated under reduced pressure. The crude product was purified by recrystallization from cold hexane to afford white crystalline 1,4-dibromo-2-butene (A) (62.4 g, 0.29 mmol) in 58% yield. Thin layer chromatography (TLC) showed an Rf value of 0.74 (unfolding agent ratio hexane:ethyl acetate = 4:1). Nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 300.40 MHz, CDCl3) data were as follows: δ 3.89-4.02 (m, 4H), 5.90-6.05 (m, 2H) ppm.

Purification Methods

Crystallise the dibromide from ligroin and/or distil it in a vacuum. [Beilstein 1 IV 79.]

References

[1] Journal of the American Chemical Society, 2014, vol. 136, # 43, p. 15403 - 15413
[2] Patent: US2008/262271, 2008, A1. Location in patent: Page/Page column 6
[3] Patent: WO2006/38764, 2006, A1. Location in patent: Page/Page column 9-10
[4] Chemische Berichte, 1938, vol. 71, p. 1679
[5] Angewandte Chemie, 1938, vol. 51, p. 919

(E)-1,4-Dibromobut-2-ene Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-dibromo-2,3-butanediol DL-Dithiothreitol
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(E)-1,4-Dibromobut-2-ene Suppliers

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View Lastest Price from (E)-1,4-Dibromobut-2-ene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
(E)-1,4-Dibromobut-2-ene 821-06-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
Henan Fengda Chemical Co., Ltd
Product
(E)-1,4-Dibromobut-2-ene 821-06-7
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-26
Weijer International Trade (Hebei) Co., Ltd
Product
(2E)-1,4-Dibromo-2-butene 821-06-7
Price
US $99.00/kg
Min. Order
1kg
Purity
>99%
Supply Ability
50000kg/Month
Release date
2023-03-07

821-06-7, (E)-1,4-Dibromobut-2-eneRelated Search:

CIS-BUTENEDIOIC ANHYDRIDE Maleic acid CIS-2-BUTENE Fumaric acid 1,3-Dibromo-5,5-dimethylhydantoin 1,3-Dibromopropane 2-Butene 3-METHYL-3-BUTEN-1-OL trans,trans-2,4-Undecadienal 1-BUTENE TRAUMATIC ACID TRANS-2-OCTENOIC ACID trans-2-Octenoic acid methyl ester trans-2-Pentenal (+/-)-trans-1,2-Diaminocyclohexane TRANS-1,4-CYCLOHEXANEDIOL trans-1,2-Cyclopentanediol TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID

  • (2E)-1,4-Dibromo-2-butene
  • (E)-1,4-Dibromo-2-butene
  • 1,4-Dibromo-2-butene, E
  • 1,4-trans-Dibromobutene-2
  • 2-Butene, 1,4-dibromo-, trans-
  • 4-dibromo-(e)-2-buten
  • 1,4-DIBROMO-2-PENTENE
  • Trans1butene4-dibroMo -2-
  • trans-1,4-DibroMo-2-butene 99%
  • 1,4-dibroMo-2-butene (trans)
  • <i>trans</i>-1,4-Dibromo-2-butene
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  • Dibromobutene
  • 1,4-DIBROMO-2-BUTENE, 99%, PREDOMINANTLY TRANS
  • 1,4-Dibromo-2-Butene,~97%
  • 2-Butene, 1,4-dibromo-, (2E)-
  • 1,4-Dibromo-1-butene
  • 4-dibromo- trans-2-butene
  • 1,4-dibromo-, trans-
  • (E)-1,4-Dibromobut-2-ene
  • trans-1,4-Dibromo-2-butene
  • trans-1,4-DibroMo-2-butene, 97% 100GR
  • trans-1,4-DibroMo-2-butene, 97% 25GR
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  • 1,4-Dibromo-trans-2-butene
  • trans-1,4-Dibromo-2-butene,97%
  • trans-1,4-Dibromo-2-butene ,99%
  • (E)-1,4-Dibromobut-2
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  • 4-DibroMo-2-butene
  • trans-1,4-Dibromo-2-butene&gt
  • trans-1,4-Dibrombut-2-en
  • (E)-1,4-Dibromobut-2-ene ISO 9001：2015 REACH
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  • TIANFUCHEM--821-06-7---(E)-1,4-Dibromobut-2-ene
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