Sorafenib Impurity 6
- Product Name
- Sorafenib Impurity 6
- CAS No.
- 1285533-84-7
- Chemical Name
- Sorafenib Impurity 6
- Synonyms
- Deschloro Sorafenib;Sorafenib impurity Y;Sorafenib impurities173;Sorafenib Deschloro Impurity;N-methyl-4-(4-(3-(3-(trifluoromethyl);N-methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide;4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methylpyridine-2-carboxamide;2-Pyridinecarboxamide, N-methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-;Sorafenib impurity 2/Deschloro Sorafenib/N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide;N-Methyl-4-[4-[[[3-(trifluoromethyl)phenyl]carbamoyl]amino]phenoxy]pyridine-2-carboxamide (as per EP) N-Methyl-4-{4-[3-(3-trifluoromethylphenyl)ureido]phenoxy}picolinamide (as per USP)
- CBNumber
- CB33129352
- Molecular Formula
- C21H17F3N4O3
- Formula Weight
- 430.38
- MOL File
- 1285533-84-7.mol
Sorafenib Impurity 6 Property
- Melting point:
- 187.6 °C
- Boiling point:
- 498.1±45.0 °C(Predicted)
- Density
- 1.399±0.06 g/cm3(Predicted)
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.39±0.70(Predicted)
- color
- Off-White to Light Brown
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M331390
- Product name
- N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide
- Packaging
- 1g
- Price
- $1390
- Updated
- 2021/12/16
- Product number
- 153512
- Product name
- N-Methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide
- Purity
- 95%
- Packaging
- 1g
- Price
- $2550
- Updated
- 2021/12/16
- Product number
- 153512
- Product name
- N-Methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide
- Purity
- 95%
- Packaging
- 250mg
- Price
- $765
- Updated
- 2021/12/16
Sorafenib Impurity 6 Chemical Properties,Usage,Production
Uses
N-Methyl-4-[4-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic.