ChemicalBook > CAS DataBase List > MPEG12-NH2

MPEG12-NH2

Product Name: MPEG12-NH2
CAS No.: 1977493-48-3
Chemical Name: MPEG12-NH2
Synonyms: 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine;m-PEG13-amine;m-PEG12-amine ，S0603;mPEG12-NH2/3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine
CBNumber: CB33145592
Molecular Formula: C25H53NO12
Formula Weight: 559.69
MOL File: 1977493-48-3.mol

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MPEG12-NH2 Property

Boiling point:: 583.6±45.0 °C(Predicted)
Density: 1.073±0.06 g/cm3(Predicted)
storage temp.: -20°C, protect from light, stored under nitrogen
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 8.74±0.10(Predicted)
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C25H53NO12/c1-27-4-5-29-8-9-31-12-13-33-16-17-35-20-21-37-24-25-38-23-22-36-19-18-34-15-14-32-11-10-30-7-6-28-3-2-26/h2-26H2,1H3
InChIKey: MSKSQCLPULZWNO-UHFFFAOYSA-N
SMILES: C(N)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-21112
Product name: m-PEG12-amine
Purity: 98%
Packaging: 1g
Price: $600
Updated: 2021/12/16

Activate Scientific

Product number: AS104096
Product name: mPEG12-NH2
Purity: 95+%
Packaging: 1g
Price: $787
Updated: 2021/12/16

Acrotein

Product number: B-0986
Product name: mPEG12-NH2
Purity: 97%
Packaging: 0.25g
Price: $293.34
Updated: 2021/12/16

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MPEG12-NH2 Chemical Properties,Usage,Production

Description

m-PEG12-amine is a monodisperse PEG linker containing an amino group, It is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

IC 50

PEGs; Non-cleavable Linker

References

[1] Vasco AV, et al. A Multicomponent Stapling Approach to Exocyclic Functionalized Helical Peptides: Adding Lipids, Sugars, PEGs, Labels, and Handles to the Lactam Bridge. Bioconjug Chem. 2019 Jan 16;30(1):253-259. DOI:10.1021/acs.bioconjchem.8b00906
[2] Joseph Fox, et al. Methods for inducing bioorthogonal reactivity. WO2017106427A1.

MPEG12-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from MPEG12-NH2 manufacturers

LAURENT

Product: mPEG12-NH2 1977493-48-3
Price: US $758.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-20

Xian confluore Biological Technology Co., Ltd.

Product: m-PEG12-amine 1977493-48-3
Price: US $0.00/g
Min. Order: 5g
Purity: >95.00%
Supply Ability: 5g
Release date: 2024-03-27

1977493-48-3, MPEG12-NH2Related Search:

2,5,8,11,14,17-Hexaoxanonadecan-19-amine 2-(2-Methoxyethoxy)ethanamine 3,6,9,12-tetraoxatridecylamine m-PEG10-amine 2,5,8,11,14,17,20-Heptaoxadocosan-22-amine 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine 2,5,8,11,14-Pentaoxahexadecan-16-amine 2-[2-(2-methoxyethoxy)ethoxy]ethylamine 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine alpha, oMega-Dipropionic acid hexaethylene glycol mPEG12-OH 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontane-1-thiol MPEG11-CH2CH2COOH MPEG12-N3 MPEG12-Mal mPEG12-Br m-PEG12-OTs

m-PEG13-amine

3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine

mPEG12-NH2/3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine

m-PEG12-amine ，S0603

1977493-48-3