General description Application Product Introduction
ChemicalBook > CAS DataBase List > 2-Bromothiophene

2-Bromothiophene

General description Application Product Introduction
Product Name
2-Bromothiophene
CAS No.
1003-09-4
Chemical Name
2-Bromothiophene
Synonyms
S0502;DKIIR;NSC 4456;INDIP-020;forTipepidine;2-Bromthiophen;Thienyl bromide;2-bromo-thiophen;2-BROMOTHIOPHENE;2-Bromothiaphene
CBNumber
CB3335815
Molecular Formula
C4H3BrS
Formula Weight
163.04
MOL File
1003-09-4.mol
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2-Bromothiophene Property

Melting point:
-10 °C
Boiling point:
149-151 °C (lit.)
Density 
1.684 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.586(lit.)
Flash point:
140 °F
storage temp. 
2-8°C
form 
Liquid
Specific Gravity
1.684
color 
Clear colorless to slightly brownish
Water Solubility 
IMMISCIBLE
Sensitive 
Light Sensitive
BRN 
104663
InChIKey
TUCRZHGAIRVWTI-UHFFFAOYSA-N
CAS DataBase Reference
1003-09-4(CAS DataBase Reference)
NIST Chemistry Reference
Thiophene, 2-bromo-(1003-09-4)
EPA Substance Registry System
Thiophene, 2-bromo- (1003-09-4)
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Safety

Hazard Codes 
T,N,Xn
Risk Statements 
10-25-41-51/53-36/37/38-23/24-22-20/21/22
Safety Statements 
26-36/37/39-45-61-16-36
RIDADR 
UN 2929 6.1/PG 2
WGK Germany 
3
F 
8
Hazard Note 
Irritant
TSCA 
T
HazardClass 
6.1
PackingGroup 
II
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H300Fatal if swallowed

H318Causes serious eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
124168
Product name
2-Bromothiophene
Purity
98%
Packaging
10g
Price
$41.6
Updated
2024/03/01
Sigma-Aldrich
Product number
124168
Product name
2-Bromothiophene
Purity
98%
Packaging
50g
Price
$72.5
Updated
2024/03/01
TCI Chemical
Product number
B0941
Product name
2-Bromothiophene
Purity
>98.0%(GC)
Packaging
25g
Price
$21
Updated
2024/03/01
TCI Chemical
Product number
B0941
Product name
2-Bromothiophene
Purity
>98.0%(GC)
Packaging
250g
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
A11959
Product name
2-Bromothiophene, 98+%
Packaging
50g
Price
$51.8
Updated
2024/03/01
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2-Bromothiophene Chemical Properties,Usage,Production

General description

2-Bromothiophene undergoes metallation-alkylation reaction with various electrophiles to generate various 5-alkylated 2-bromo products. It is coupled with 4-bromoallyl phenyl ether to produce allyl thiophene ether, which is a new type of organic thin film transistor dielectric material.

Application

In dimethylformamide containing tetramethylammonium perchlorate, 2-bromothiophene is electrochemically reduced many mono- and dihalothiophenes on a carbon cathode by cyclic voltammetry and controlled potential electrolysis.

Product Introduction

The 2-Bromothiophene(casno:1003-09-4) is an organic compound with the formula C4H3BrS. The IUPAC name of this chemical is 2-bromothiophene. With the CAS registry number 1003-09-4, it is also named as Bromothiophene. The product's categories are Thiophenes; Halides; Thiophenes & Benzothiophenes; Thiophene & Benzothiophene; Thiophenes & Benzothiophenes. Besides, 2-Bromothiophene(casno:1003-09-4) is a colorless to light yellow transparent liquid, which should be stored in a closed dark and cool place. 2-Bromothiophene(casno:1003-09-4) can be used for organic synthesis and pharmaceutical intermediates.

Chemical Properties

colorless to light yellow liquid. Soluble in ether and acetone, insoluble in water.

Uses

2-Bromothiophene has been used in electrochemical reduction of a number of mono- and dihalothiophenes at carbon cathodes in dimethylformamide containing tetramethylammonium per chlorate by cyclic voltammetry and controlled-potential electrolysis.

Preparation

2-Bromothiophene is synthesized by bromination of thiophene, which is achieved through the following steps: dissolve thiophene in acetic acid, and add bromine in glacial acetic acid solution below 10°C. Water was added to the reaction mixture to precipitate an oily liquid. Extract with ether. Add potassium carbonate to the extract to remove acetic acid, dry it, distill off the ether, and then conduct vacuum distillation to collect fractions at 42-46°C (1.73kPa) to obtain 2-bromothiophene with a yield of 55%.

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 5474, 1957 DOI: 10.1021/ja01577a039
Synthesis, p. 890, 1988 DOI: 10.1055/s-1988-27740

General Description

2-Bromothiophene undergoes metalation-alkylation reaction with various electrophiles to form various 5-alkylated 2-bromo products. It undergoes coupling with 4-bromo allyl phenyl ether to form allyl phenyl thiophene ether, which is a novel potential dielectric material for organic thin film transistors.

2-Bromothiophene Preparation Products And Raw materials

Raw materials

Acetic acid solution

Preparation Products

4,6-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 2-(METHYLTHIO)THIOPHENE 5-(METHYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID 2-AMIDINOTHIOPHENE HYDROCHLORIDE 5-DIMETHYLAMINO-THIOPHENE-2-CARBALDEHYDE 2-Bromo-5-nitrothiophene 2,2':5',2''-TERTHIOPHENE 5-Bromothiophene-2-carbaldehyde 5-(METHYLTHIO)THIOPHENE-2-CARBOXYLIC ACID 6-(2-THIENYL)-2-PYRIDINECARBOXALDEHYDE 2-(5-BROMO-2-THIENYL)-3-CHLOROQUINOXALINE
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View Lastest Price from 2-Bromothiophene manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
2-Bromothiophene 1003-09-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-25
airuikechemical co., ltd.
Product
2-bromothiophene 1003-09-4
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-09
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Bromothiophene 1003-09-4
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-19

1003-09-4, 2-BromothiopheneRelated Search:

Tetrahydrothiophene Cephalothin sodium Ethidium bromide Allyl bromide Thiophene Rocuronium bromide Vecuronium bromide Thifensulfuron methyl Dibenzothiophene Sodium bromate Dimidium bromide Methyl bromide Tetrabromothiophene 2,3,5-Tribromothiophene 2,5-Dibromothiophene 4,5-Dibromothiophene-2-sulphonyl chloride 2,5-DIBROMO-3,4-DINITROTHIOPHENE 5-Bromothiophene-2-carbaldehyde

  • TIMTEC-BB SBB003931
  • 2 - broMine thiophene
  • 2-bromothiophene:2-thienyl bromide
  • INDIP-020
  • Clopidogrel Impurity 74
  • 2-BROMOTHIOPHENE, 98%2-BROMOTHIOPHENE, 98%2-BROMOTHIOPHENE, 98%2-BROMOTHIOPHENE, 98%
  • 2-THIENYL BROMIDE
  • 2-BROMOTHIOPHENE
  • ALPHA-THIENYL BROMIDE
  • 2-bromo-thiophen
  • Thienyl bromide
  • thiophene,2-bromo-
  • 2-Bromothiophene99%
  • 2-Bromothiophene, 98+%
  • forTipepidine
  • 2-Bromothiaphene
  • 2-BroMothiophene, 98% 50ML
  • NSC 4456
  • 2-BROMOTHIOPHENE FOR SYNTHESIS
  • 2-Bromothiophene &gt
  • 2-Bromothiophene ISO 9001：2015 REACH
  • S0502
  • 2-Bromothiophene pure, 98%
  • Tiotropium Bromide Impurity 9
  • 2-Bromothiophene CAS NO.1003-09-4
  • DKIIR
  • 2-Dibromothiophene
  • 2-Bromothiophene in isooctane
  • 2-Bromthiophen
  • 1003-09-4
  • 10003-09-4
  • C4H3BrS
  • C4H3SBr
  • HALOGEN
  • Building Blocks
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Thiophenes
  • Heterocycle-oher series
  • Thiophene&Benzothiophene
  • Thiophenes & Benzothiophenes
  • Halides
  • Thiophenes & Benzothiophenes
  • Heterocycles
  • Sulfur & Selenium Compounds
  • Thiophenes
  • bc0001
  • K00001