ChemicalBook > CAS DataBase List > CU-CPT-9a

CU-CPT-9a

Product Name
CU-CPT-9a
CAS No.
2162962-69-6
Chemical Name
CU-CPT-9a
Synonyms
CPD1577;CU-CPT-9a;TLR8 inhibitor;cas 2162962-69-6;TLR8-specific antagonist 1;4-(4-hydroxy-3-methylphenyl)quinolin-7-ol;CU-CPT-9A;CAS 2162962-69-6;TLR8 INHIBITOR;2-Methyl-4-(7-hydroxy-4-quinolinyl)phenol;7-Quinolinol, 4-(4-hydroxy-3-methylphenyl)-;inhibit,Toll-like Receptor (TLR),CU-CPT9b,Inhibitor,CUCPT9b,CU CPT9b
CBNumber
CB33369600
Molecular Formula
C16H13NO2
Formula Weight
251.28
MOL File
2162962-69-6.mol
More
Less

CU-CPT-9a Property

Boiling point:
452.6±45.0 °C(Predicted)
Density 
1.287±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
form 
A crystalline solid
pka
8.46±0.20(Predicted)
color 
White to yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
28723
Product name
CU-CPT9b
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
28723
Product name
CU-CPT9b
Packaging
25mg
Price
$494
Updated
2024/03/01
Cayman Chemical
Product number
28723
Product name
CU-CPT9b
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
28723
Product name
CU-CPT9b
Packaging
10mg
Price
$214
Updated
2024/03/01
Tocris
Product number
6479
Product name
CUCPT9a
Purity
≥98%(HPLC)
Packaging
5
Price
$171
Updated
2021/12/16
More
Less

CU-CPT-9a Chemical Properties,Usage,Production

Description

CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF-ĸB induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.

Uses

CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.

CU-CPT-9a Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

CU-CPT-9a Suppliers

ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8012
Advantage
62
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1925
Advantage
55
Twochem Co.Ltd.
Tel
021-58111628 15800915896
Fax
QQ 3285589261
Email
sales@twochem.com
Country
China
ProdList
1788
Advantage
58
Jinan Yaoyan Pharmaceutical Co., Ltd.
Tel
Fax
-
Email
jnyaoyan@163.com
Country
China
ProdList
3069
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd.
Tel
18081075745
Email
chemflowtech@sina.com
Country
China
ProdList
1886
Advantage
58

2162962-69-6, CU-CPT-9aRelated Search:


  • CPD1577
  • CU-CPT-9a
  • 2-Methyl-4-(7-hydroxy-4-quinolinyl)phenol
  • cas 2162962-69-6
  • CU-CPT-9A;CAS 2162962-69-6;TLR8 INHIBITOR
  • TLR8 inhibitor
  • TLR8-specific antagonist 1
  • 4-(4-hydroxy-3-methylphenyl)quinolin-7-ol
  • 7-Quinolinol, 4-(4-hydroxy-3-methylphenyl)-
  • inhibit,Toll-like Receptor (TLR),CU-CPT9b,Inhibitor,CUCPT9b,CU CPT9b
  • 2162962-69-6