CU-CPT-9a
- Product Name
- CU-CPT-9a
- CAS No.
- 2162962-69-6
- Chemical Name
- CU-CPT-9a
- Synonyms
- CPD1577;CU-CPT-9a;TLR8 inhibitor;cas 2162962-69-6;TLR8-specific antagonist 1;4-(4-hydroxy-3-methylphenyl)quinolin-7-ol;CU-CPT-9A;CAS 2162962-69-6;TLR8 INHIBITOR;2-Methyl-4-(7-hydroxy-4-quinolinyl)phenol;7-Quinolinol, 4-(4-hydroxy-3-methylphenyl)-;inhibit,Toll-like Receptor (TLR),CU-CPT9b,Inhibitor,CUCPT9b,CU CPT9b
- CBNumber
- CB33369600
- Molecular Formula
- C16H13NO2
- Formula Weight
- 251.28
- MOL File
- 2162962-69-6.mol
CU-CPT-9a Property
- Boiling point:
- 452.6±45.0 °C(Predicted)
- Density
- 1.287±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form
- A crystalline solid
- pka
- 8.46±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 28723
- Product name
- CU-CPT9b
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 28723
- Product name
- CU-CPT9b
- Packaging
- 25mg
- Price
- $494
- Updated
- 2024/03/01
- Product number
- 28723
- Product name
- CU-CPT9b
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 28723
- Product name
- CU-CPT9b
- Packaging
- 10mg
- Price
- $214
- Updated
- 2024/03/01
- Product number
- 6479
- Product name
- CUCPT9a
- Purity
- ≥98%(HPLC)
- Packaging
- 5
- Price
- $171
- Updated
- 2021/12/16
CU-CPT-9a Chemical Properties,Usage,Production
Description
CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF-ĸB induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
Uses
CU-CPT9a is a potent TLR8 inhibitor (IC50 = 0.5 nM and Kd = 21 nM). Stabilizes the TLR8 dimer in its resting state, preventing activation. Suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
CU-CPT-9a Preparation Products And Raw materials
Raw materials
Preparation Products
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