2-Bromo-3,5-dichloropyridine

Product Name: 2-Bromo-3,5-dichloropyridine
CAS No.: 14482-51-0
Chemical Name: 2-Bromo-3,5-dichloropyridine
Synonyms: 2-Bromo-3,5-dichL;AKOS BBS-00001365;5-Dichloro-2-broMopyridine;2-BROMO-3,5-DICHLOROPYRIDINE;3,5-DICHLORO-2-BROMOPYRIDINE;2-BROMO-3,5-DICHLOROPYRIDUNE;PYRIDINE, 2-BROMO-3,5-DICHLORO-;2-Bromo-3,5-dichloropyridine >3,5-DICHLORO-2-BROMOPYRIDINE 98+%;3,5-DICHLOROPYRIDIN-2-YL-BORONIC ACID
CBNumber: CB3339772
Molecular Formula: C5H2BrCl2N
Formula Weight: 226.89
MOL File: 14482-51-0.mol

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2-Bromo-3,5-dichloropyridine Property

Melting point:: 40-42
Boiling point:: 243.3±35.0 °C(Predicted)
Density: 1.848±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: -2.37±0.10(Predicted)
form: Solid
color: Pale brown
InChI: InChI=1S/C5H2BrCl2N/c6-5-4(8)1-3(7)2-9-5/h1-2H
InChIKey: QCKPJWDIDCGQRB-UHFFFAOYSA-N
SMILES: C1(Br)=NC=C(Cl)C=C1Cl
CAS DataBase Reference: 14482-51-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38-41-37/38-25
Safety Statements: 26-45-39
Hazard Note: Irritant
HazardClass: 6.1
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS003979
Product name: 2-Bromo-3,5-dichloropyridine
Purity: AldrichCPR
Packaging: 250mg
Price: $70.9
Updated: 2024/03/01

TCI Chemical

Product number: B3734
Product name: 2-Bromo-3,5-dichloropyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: B3734
Product name: 2-Bromo-3,5-dichloropyridine
Purity: >98.0%(GC)
Packaging: 25g
Price: $130
Updated: 2025/07/31

TRC

Product number: B691168
Product name: 2-Bromo-3,5-dichloropyridine
Packaging: 5g
Price: $75
Updated: 2021/12/16

TRC

Product number: B691168
Product name: 2-Bromo-3,5-dichloropyridine
Packaging: 500mg
Price: $45
Updated: 2021/12/16

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2-Bromo-3,5-dichloropyridine Chemical Properties,Usage,Production

Uses

2-Bromo-3,5-dichloropyridine is used in various fields, including pharmaceuticals, agrochemicals, and materials science. It is an essential intermediate for the synthesis of different chemical compounds, such as fungicides, herbicides, and insecticides.

Synthesis

4214-74-8

14482-51-0

Step 1: Synthesis of 2-bromo-3,5-dichloropyridine To a solution of 3,5-dichloropyridin-2-amine (1.0 g, 6.2 mmol) dissolved in 40% aqueous hydrobromic acid (8 mL), bromine (2.8 g, 17 mmol) was slowly added dropwise at -20 °C. The resulting orange-colored suspension was stirred continuously for 2 hours at -20 °C. Subsequently, aqueous sodium nitrite (1.1 g, 17 mmol) was added at the same temperature. The reaction mixture was warmed up to ambient temperature and stirring was continued for 2 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and the pH was adjusted with 30% aqueous sodium hydroxide solution to about 12. The reaction mixture was extracted with ether to give a light yellow organic phase. The organic phases were combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the title compound 2-bromo-3,5-dichloropyridine as a yellow solid (730 mg, 52% yield). 1H NMR (400MHz, CDCl3) δ 8.27 (d, J=2.3Hz, 1H).

References

[1] Patent: US4510148, 1985, A
[2] Patent: WO2008/70908, 2008, A1. Location in patent: Page/Page column 71-72
[3] Patent: WO2015/187845, 2015, A1. Location in patent: Paragraph 0239
[4] European Journal of Medicinal Chemistry, 1989, vol. 24, # 3, p. 249 - 258
[5] Phosphorus and Sulfur and the Related Elements, 1987, vol. 34, p. 123 - 132

2-Bromo-3,5-dichloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-3,5-dichloropyridine Suppliers

Americas 1 China 242 Europe 3 France 2 Germany 4 India 22 Japan 1 United Kingdom 13 United States 43 Global 331

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 023-13650506873 19923294409
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INTATRADE GmbH

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TCI (Shanghai) Development Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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Energy Chemical

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Shijiazhuang Sdyano Fine Chemical Co., Ltd.

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View Lastest Price from 2-Bromo-3,5-dichloropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Bromo-3,5-dichloropyridine 14482-51-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-30

Henan Fengda Chemical Co., Ltd

Product: 2-Bromo-3,5-dichloropyridine 14482-51-0
Price: US $5.00-0.10/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-09

Honest Joy Holdings Limited

Product: 2-Bromo-3,5-dichloropyridine 14482-51-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.4%
Supply Ability: 100 tons
Release date: 2022-01-26

14482-51-0, 2-Bromo-3,5-dichloropyridineRelated Search:

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2-BROMO-3,5-DICHLOROPYRIDINE

3,5-DICHLOROPYRIDIN-2-YL-BORONIC ACID

3,5-DICHLORO-2-BROMOPYRIDINE

AKOS BBS-00001365

3,5-DICHLORO-2-BROMOPYRIDINE 98+%

5-Dichloro-2-broMopyridine

PYRIDINE, 2-BROMO-3,5-DICHLORO-

2-BROMO-3,5-DICHLOROPYRIDUNE

2-Bromo-3,5-dichloropyridine &gt

2-Bromo-3,5-dichL

2-Bromo-3,5-dichloropyridine ISO 9001：2015 REACH

14482-51-0

C5H2BrCl2N

Pyridine series

Halides

blocks

Bromides

Pyridines

Pyridines, Pyrimidines, Purines and Pteredines