2-Bromo-3,5-dichloropyridine
- Product Name
- 2-Bromo-3,5-dichloropyridine
- CAS No.
- 14482-51-0
- Chemical Name
- 2-Bromo-3,5-dichloropyridine
- Synonyms
- 2-Bromo-3,5-dichL;AKOS BBS-00001365;5-Dichloro-2-broMopyridine;2-BROMO-3,5-DICHLOROPYRIDINE;3,5-DICHLORO-2-BROMOPYRIDINE;2-BROMO-3,5-DICHLOROPYRIDUNE;PYRIDINE, 2-BROMO-3,5-DICHLORO-;2-Bromo-3,5-dichloropyridine >3,5-DICHLORO-2-BROMOPYRIDINE 98+%;3,5-DICHLOROPYRIDIN-2-YL-BORONIC ACID
- CBNumber
- CB3339772
- Molecular Formula
- C5H2BrCl2N
- Formula Weight
- 226.89
- MOL File
- 14482-51-0.mol
2-Bromo-3,5-dichloropyridine Property
- Melting point:
- 40-42
- Boiling point:
- 243.3±35.0 °C(Predicted)
- Density
- 1.848±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- -2.37±0.10(Predicted)
- form
- Solid
- color
- Pale brown
- InChI
- InChI=1S/C5H2BrCl2N/c6-5-4(8)1-3(7)2-9-5/h1-2H
- InChIKey
- QCKPJWDIDCGQRB-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC=C(Cl)C=C1Cl
- CAS DataBase Reference
- 14482-51-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-41-37/38-25
- Safety Statements
- 26-45-39
- Hazard Note
- Irritant
- HazardClass
- 6.1
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS003979
- Product name
- 2-Bromo-3,5-dichloropyridine
- Purity
- AldrichCPR
- Packaging
- 250mg
- Price
- $70.9
- Updated
- 2024/03/01
- Product number
- B3734
- Product name
- 2-Bromo-3,5-dichloropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $33
- Updated
- 2025/07/31
- Product number
- B3734
- Product name
- 2-Bromo-3,5-dichloropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $130
- Updated
- 2025/07/31
- Product number
- B691168
- Product name
- 2-Bromo-3,5-dichloropyridine
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- B691168
- Product name
- 2-Bromo-3,5-dichloropyridine
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
2-Bromo-3,5-dichloropyridine Chemical Properties,Usage,Production
Uses
2-Bromo-3,5-dichloropyridine is used in various fields, including pharmaceuticals, agrochemicals, and materials science. It is an essential intermediate for the synthesis of different chemical compounds, such as fungicides, herbicides, and insecticides.
Synthesis
4214-74-8
14482-51-0
Step 1: Synthesis of 2-bromo-3,5-dichloropyridine To a solution of 3,5-dichloropyridin-2-amine (1.0 g, 6.2 mmol) dissolved in 40% aqueous hydrobromic acid (8 mL), bromine (2.8 g, 17 mmol) was slowly added dropwise at -20 °C. The resulting orange-colored suspension was stirred continuously for 2 hours at -20 °C. Subsequently, aqueous sodium nitrite (1.1 g, 17 mmol) was added at the same temperature. The reaction mixture was warmed up to ambient temperature and stirring was continued for 2 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and the pH was adjusted with 30% aqueous sodium hydroxide solution to about 12. The reaction mixture was extracted with ether to give a light yellow organic phase. The organic phases were combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the title compound 2-bromo-3,5-dichloropyridine as a yellow solid (730 mg, 52% yield). 1H NMR (400MHz, CDCl3) δ 8.27 (d, J=2.3Hz, 1H).
References
[1] Patent: US4510148, 1985, A
[2] Patent: WO2008/70908, 2008, A1. Location in patent: Page/Page column 71-72
[3] Patent: WO2015/187845, 2015, A1. Location in patent: Paragraph 0239
[4] European Journal of Medicinal Chemistry, 1989, vol. 24, # 3, p. 249 - 258
[5] Phosphorus and Sulfur and the Related Elements, 1987, vol. 34, p. 123 - 132
2-Bromo-3,5-dichloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-3,5-dichloropyridine Suppliers
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- Country
- France
- ProdList
- 303
- Advantage
- 58
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- France
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View Lastest Price from 2-Bromo-3,5-dichloropyridine manufacturers
- Product
- 2-Bromo-3,5-dichloropyridine 14482-51-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 2-Bromo-3,5-dichloropyridine 14482-51-0
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- 2-Bromo-3,5-dichloropyridine 14482-51-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.4%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26