ChemicalBook > CAS DataBase List > 2-Bromo-3,5-dichloropyridine

2-Bromo-3,5-dichloropyridine

Product Name
2-Bromo-3,5-dichloropyridine
CAS No.
14482-51-0
Chemical Name
2-Bromo-3,5-dichloropyridine
Synonyms
2-Bromo-3,5-dichL;AKOS BBS-00001365;5-Dichloro-2-broMopyridine;2-BROMO-3,5-DICHLOROPYRIDINE;3,5-DICHLORO-2-BROMOPYRIDINE;2-BROMO-3,5-DICHLOROPYRIDUNE;PYRIDINE, 2-BROMO-3,5-DICHLORO-;2-Bromo-3,5-dichloropyridine >3,5-DICHLORO-2-BROMOPYRIDINE 98+%;3,5-DICHLOROPYRIDIN-2-YL-BORONIC ACID
CBNumber
CB3339772
Molecular Formula
C5H2BrCl2N
Formula Weight
226.89
MOL File
14482-51-0.mol
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2-Bromo-3,5-dichloropyridine Property

Melting point:
40-42
Boiling point:
243.3±35.0 °C(Predicted)
Density 
1.848±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
-2.37±0.10(Predicted)
form 
Solid
color 
Pale brown
InChI
InChI=1S/C5H2BrCl2N/c6-5-4(8)1-3(7)2-9-5/h1-2H
InChIKey
QCKPJWDIDCGQRB-UHFFFAOYSA-N
SMILES
C1(Br)=NC=C(Cl)C=C1Cl
CAS DataBase Reference
14482-51-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-41-37/38-25
Safety Statements 
26-45-39
Hazard Note 
Irritant
HazardClass 
6.1
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003979
Product name
2-Bromo-3,5-dichloropyridine
Purity
AldrichCPR
Packaging
250mg
Price
$70.9
Updated
2024/03/01
TCI Chemical
Product number
B3734
Product name
2-Bromo-3,5-dichloropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$33
Updated
2025/07/31
TCI Chemical
Product number
B3734
Product name
2-Bromo-3,5-dichloropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$130
Updated
2025/07/31
TRC
Product number
B691168
Product name
2-Bromo-3,5-dichloropyridine
Packaging
5g
Price
$75
Updated
2021/12/16
TRC
Product number
B691168
Product name
2-Bromo-3,5-dichloropyridine
Packaging
500mg
Price
$45
Updated
2021/12/16
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2-Bromo-3,5-dichloropyridine Chemical Properties,Usage,Production

Uses

2-Bromo-3,5-dichloropyridine is used in various fields, including pharmaceuticals, agrochemicals, and materials science. It is an essential intermediate for the synthesis of different chemical compounds, such as fungicides, herbicides, and insecticides.

Synthesis

4214-74-8

14482-51-0

Step 1: Synthesis of 2-bromo-3,5-dichloropyridine To a solution of 3,5-dichloropyridin-2-amine (1.0 g, 6.2 mmol) dissolved in 40% aqueous hydrobromic acid (8 mL), bromine (2.8 g, 17 mmol) was slowly added dropwise at -20 °C. The resulting orange-colored suspension was stirred continuously for 2 hours at -20 °C. Subsequently, aqueous sodium nitrite (1.1 g, 17 mmol) was added at the same temperature. The reaction mixture was warmed up to ambient temperature and stirring was continued for 2 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and the pH was adjusted with 30% aqueous sodium hydroxide solution to about 12. The reaction mixture was extracted with ether to give a light yellow organic phase. The organic phases were combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the title compound 2-bromo-3,5-dichloropyridine as a yellow solid (730 mg, 52% yield). 1H NMR (400MHz, CDCl3) δ 8.27 (d, J=2.3Hz, 1H).

References

[1] Patent: US4510148, 1985, A
[2] Patent: WO2008/70908, 2008, A1. Location in patent: Page/Page column 71-72
[3] Patent: WO2015/187845, 2015, A1. Location in patent: Paragraph 0239
[4] European Journal of Medicinal Chemistry, 1989, vol. 24, # 3, p. 249 - 258
[5] Phosphorus and Sulfur and the Related Elements, 1987, vol. 34, p. 123 - 132

2-Bromo-3,5-dichloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Bromo-3,5-dichloropyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Bromo-3,5-dichloropyridine 14482-51-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-30
Henan Fengda Chemical Co., Ltd
Product
2-Bromo-3,5-dichloropyridine 14482-51-0
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Honest Joy Holdings Limited
Product
2-Bromo-3,5-dichloropyridine 14482-51-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98.4%
Supply Ability
100 tons
Release date
2022-01-26

14482-51-0, 2-Bromo-3,5-dichloropyridineRelated Search:

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  • AKOS BBS-00001365
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  • PYRIDINE, 2-BROMO-3,5-DICHLORO-
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  • 2-Bromo-3,5-dichloropyridine &gt
  • 2-Bromo-3,5-dichL
  • 2-Bromo-3,5-dichloropyridine ISO 9001：2015 REACH
  • 14482-51-0
  • C5H2BrCl2N
  • Pyridine series
  • Halides
  • blocks
  • Bromides
  • Pyridines
  • Pyridines, Pyrimidines, Purines and Pteredines