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Boc-O-benzyl-L-tyrosine

Product Name
Boc-O-benzyl-L-tyrosine
CAS No.
2130-96-3
Chemical Name
Boc-O-benzyl-L-tyrosine
Synonyms
BOC-TYR(BZL);Boc-L-Tyr(Bzl);BOC-TYR(BZL)-OH;Boc-Tyr(Bz1)-OH;Boc-Tyr(BzI)-0H;BOC-L-TYR(BZL)-OH;BOC-O-BENZYL-L-TYR;BOC-L-Tyr(OBZL)-OH;Boc-Tyr(Bzl)-OH 98%;BOC-TYROSINE(BZL)-OH
CBNumber
CB3341577
Molecular Formula
C21H25NO5
Formula Weight
371.43
MOL File
2130-96-3.mol
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Boc-O-benzyl-L-tyrosine Property

Melting point:
110-112 °C
alpha 
27 º (c=2% in ethanol)
Boiling point:
552.4±50.0 °C(Predicted)
Density 
1.185±0.06 g/cm3(Predicted)
refractive index 
29.5 ° (C=2, EtOH)
storage temp. 
Store below +30°C.
solubility 
almost transparency in EtOH
pka
2.99±0.10(Predicted)
form 
Powder or Crystalline Powder
color 
White
optical activity
[α]20/D +27.0±1.5°, c = 2% in ethanol
BRN 
2227416
CAS DataBase Reference
2130-96-3(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29242990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.53056
Product name
Boc-Tyr(Bzl)-OH
Purity
Novabiochem?
Packaging
25g
Price
$69.1
Updated
2025/07/31
Sigma-Aldrich
Product number
8.53056
Product name
Boc-Tyr(Bzl)-OH
Purity
Novabiochem?
Packaging
100g
Price
$212
Updated
2025/07/31
Sigma-Aldrich
Product number
15410
Product name
Boc-Tyr(Bzl)-OH
Purity
≥99.0% (T)
Packaging
5g
Price
$41.2
Updated
2023/06/20
TCI Chemical
Product number
B1631
Product name
N-(tert-Butoxycarbonyl)-O-benzyl-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$42
Updated
2025/07/31
TCI Chemical
Product number
B1631
Product name
N-(tert-Butoxycarbonyl)-O-benzyl-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$114
Updated
2025/07/31
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Boc-O-benzyl-L-tyrosine Chemical Properties,Usage,Production

Chemical Properties

Light yellow powder

Uses

Boc-Tyr(Bzl)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

3978-80-1

100-39-0

2130-96-3

Example 2: To a solution of N-Boc-L-tyrosine (281 mg, 1.0 mmol) in methanol (0.5 mL) was added 28% sodium methanol-methanol solution (0.42 mL, 2.1 mmol) and benzyl bromide (162 μL, 1.4 mmol). The reaction mixture was stirred at 40 °C for 3 hours. After completion of the reaction, water (2 mL) was added to homogenize the system and the reaction system was analyzed by high performance liquid chromatography (HPLC). The analysis confirmed the generation of the target product (S)-3-(4-(benzyloxy)phenyl)-2-((tert-butoxycarbonyl)amino)propionic acid (353 mg, 95% conversion).

References

[1] Patent: US2005/283021, 2005, A1. Location in patent: Page/Page column 6
[2] European Journal of Organic Chemistry, 2015, vol. 2015, # 14, p. 3057 - 3062
[3] European Journal of Medicinal Chemistry, 2016, vol. 114, p. 318 - 327
[4] Patent: CN107954937, 2018, A. Location in patent: Paragraph 0032-0034

Boc-O-benzyl-L-tyrosine Preparation Products And Raw materials

Raw materials

H-TYR(BZL)-OH 1,4-Dioxane Ethyl acetate

Preparation Products

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Boc-O-benzyl-L-tyrosine Suppliers

Americas 1 Canada 1 China 214 Europe 3 France 1 Germany 5 Hungary 1 India 13 Japan 7 South Korea 1 Switzerland 4 United Kingdom 10 United States 47 Global 308
Reanal Finechemical Private Ltd.
Tel
--
Fax
--
Email
sales@reanal.hu
Country
Hungary
ProdList
132
Advantage
50
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View Lastest Price from Boc-O-benzyl-L-tyrosine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-Tyr(bzl)-OH 2130-96-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-11-16
Honest Joy Holdings Limited
Product
Boc-tyr(bzl)-oh 2130-96-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99.1%
Supply Ability
100 tons
Release date
2022-01-26
Career Henan Chemical Co
Product
Boc-O-benzyl-L-tyrosine 2130-96-3
Price
US $10.00/KG
Min. Order
10KG
Purity
99%
Supply Ability
100kg
Release date
2018-07-31

2130-96-3, Boc-O-benzyl-L-tyrosineRelated Search:

Benzyl benzoate H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH tert-Butyl carbazate Prostratin, PKC activator Benzyl alcohol PYRAZOPHOS L-Tyrosine Benzyl bromide Boc-Aib-OH CARBONYL SULFIDE N-Carbobenzyloxyglycine Boc-D-Tyr-OH BOC-L-Proline Boc-Ser(tBu)-OH N-BOC-O-Benzyl-L-serine Boc-Lys-OH BOC-GLY-LEU-OH BOC-TYR(2,6-DI-CL-BZL)-OH

  • BOC-O-BENZYL-L-TYROSINE
  • BOC-O-BENZYL-L-TYR
  • BOC-L-TYR(BZL)-OH
  • BOC-(S)-2-AMINO-3-(4'-BENZYLOXYPHENYL)PROPANOIC ACID
  • BOC-TYR(BZL)
  • BOC-TYR(BZL)-OH
  • BOC-TYROSINE(BZL)-OH
  • T-BUTYLOXYCARBONYL-O-BENZYL-L-TYROSINE
  • N-BOC-O-BENZYL-L-TYROSINE
  • N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-L-TYROSINE
  • N-ALPHA-T-BUTOXYCARBONYL-O-BENZYL-L-TYROSINE
  • N-ALPHA-T-BOC-O-BENZYL-L-TYROSINE
  • N-(TERT-BUTOXYCARBONYL)-O-BENZYL-L-TYROSINE
  • N-TERT-BUTOXYCARBONYL-O-BENZYL-L-TYRISINE
  • N-T-BUTOXYCARBONYL-O-BENZYL-L-TYROSINE
  • (2S)-3-[4-(benzyloxy)phenyl]-2-{[(tert-butoxy)carbonyl]amino}propanoic acid
  • Boc-Tyr(Bzl)-OH 98%
  • Butoxycarbonylbenzyltyrisine
  • N-T-boc-O-benzyl-L-tyrosine crystalline
  • O-benzyl-N-[(tert-butoxy)carbonyl]-L-tyrosine
  • Boc-L-Tyr(Bzl)
  • N-ALPHA-TERT-BUTYLOXYCABONYL-O-BENZYL-L-TYROSINE
  • N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-L-TYROSINE
  • BOC-(O-BENZYL)-TYROSINE
  • N-(tert-Butoxycarbonyl)-4-(benzyloxy)-L-phenylalanine
  • N-(tert-Butoxycarbonyl)-4-(benzyloxy)phenylalanine
  • N-[(tert-Butyloxy)carbonyl]-O-benzyl L-tyrosine
  • N-Boc-O-Benzyltyrosine
  • O-Benzyl-N-(tert-butyloxycarbonyl)-L-tyrosine
  • 3-[4-hydroxy-2-(phenylmethyl)phenyl]-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoic acid
  • N-Boc-O-benzyl-L-tyrosine Boc-Tyr(Bzl)-OH
  • Boc-Tyr(Bz1)-OH
  • (S)-3-(4-(benzyloxy)phenyl)-2-((tert-butoxycarbonyl)aMino)propanoic acid
  • Boc-O-benzyl-L-tyros
  • Boc-Tyr(Bzl)-OH >=99.0% (T)
  • (2S)-2-(tert-butoxycarbonylamino)-3-[4-(phenylmethoxy)phenyl]propanoic acid
  • (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-(phenylmethoxy)phenyl]propanoic acid
  • (2S)-2-[(tert-butoxy-oxomethyl)amino]-3-[4-(phenylmethoxy)phenyl]propanoic acid
  • (2S)-3-[4-(benzyloxy)phenyl]-2-(tert-butoxycarbonylamino)propionic acid
  • (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoic aci
  • N-Boc-4-benzyloxy-L-phenylalanine
  • Boc-O-benzyl-L-tyrosine99%
  • (Tert-Butoxy)Carbonyl Tyr(Bzl)-OH
  • N-(tert-Butoxycarbonyl)-O-benzyl-L-tyrosine &gt
  • BOC-TYR(BZL)-OH 25 G
  • L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-
  • Boc-O-benzyl-L-tyrosine USP/EP/BP
  • N-BOC-O-Benzyl-L-Tyrosine extrapure, 98%
  • BOC-L-Tyr(OBZL)-OH
  • Boc-Tyr(BzI)-0H
  • 2130-96-3
  • 21300-96-3
  • C6H5CH2OC6H4CH2CHCOOHNHCOOCCH33
  • Protected & Labeled Amino Acids
  • Boc-Amino Acids
  • Amino Acids (N-Protected)
  • Peptide Synthesis
  • Specialty Synthesis