ChemicalBook > CAS DataBase List > 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

Product Name
4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
CAS No.
21561-09-1
Chemical Name
4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
Synonyms
WHI-P258;JAK3 INHIBITOR, NEGATIVE CONTROL;4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE;6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE;6,7-dimethoxy-N-phenylquinazolin-4-amine;4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-;N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE;JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258;WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258
CBNumber
CB3348071
Molecular Formula
C16H15N3O2
Formula Weight
281.31
MOL File
Mol file
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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Property

Boiling point:
441.2±40.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml
form 
A crystalline solid
pka
6.19±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
10 mg
Price
$118
Updated
2024/03/01
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
25 mg
Price
$202
Updated
2024/03/01
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
500μg
Price
$103
Updated
2023/01/06
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
1mg
Price
$186
Updated
2023/01/06
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
5mg
Price
$74
Updated
2024/03/01
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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Chemical Properties,Usage,Production

Description

WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.

Uses

4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Suppliers

China 56 India 1 United Kingdom 2 United States 11 Global 70
VDM Biochemicals
Tel
0330-2528181
Fax
0330-2528171
Email
sales@vdmbio.com
Country
United States
ProdList
510
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64
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
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57
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
ShangHai KenEn Chemical Technology Co., Ltd.
Tel
13120367189
Fax
021-50315529
Email
mychess007@163.com
Country
China
ProdList
1994
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55
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
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55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4456
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55
D&C Chemicals
Tel
+86-21-58447131
Fax
+86-21-61642470
Email
1724405207@qq.com
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China
ProdList
472
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ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
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58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai Changyan Chem & Tech Co., Ltd.
Tel
021-20242659 18930833303
Fax
+86 (21) 2024-2659
Email
Sales@changyanchem.cn
Country
China
ProdList
5010
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55

21561-09-1, 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINERelated Search:

4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL WEHI-345 JAK3 INHIBITOR I 4-AMINO-3-CYANO-1,2,5,6-TETRAHYDROPYRIDINE WH-4-023 7-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE WHI-P97 JAK3 Inhibitor Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-

  • WHI-P258
  • JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258
  • 4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-
  • N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE
  • 6,7-dimethoxy-N-phenylquinazolin-4-amine
  • JAK3 INHIBITOR, NEGATIVE CONTROL
  • 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
  • 6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE
  • WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258
  • 21561-09-1
  • Inhibitors