ChemicalBook > CAS DataBase List > 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE

Product Name
4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
CAS No.
21561-09-1
Chemical Name
4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
Synonyms
WHI-P258;JAK3 INHIBITOR, NEGATIVE CONTROL;4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE;6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE;6,7-dimethoxy-N-phenylquinazolin-4-amine;4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-;N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE;JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258;WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258
CBNumber
CB3348071
Molecular Formula
C16H15N3O2
Formula Weight
281.31
MOL File
Mol file
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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Property

Boiling point:
441.2±40.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml
form 
A crystalline solid
pka
6.19±0.70(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
10 mg
Price
$118
Updated
2024/03/01
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
25 mg
Price
$202
Updated
2024/03/01
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
500μg
Price
$103
Updated
2023/01/06
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
1mg
Price
$186
Updated
2023/01/06
Cayman Chemical
Product number
23453
Product name
WHI-P258
Purity
≥98%
Packaging
5mg
Price
$74
Updated
2024/03/01
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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Chemical Properties,Usage,Production

Description

WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.

Uses

4-Phenylamino-6,7-dimethoxyquinazoline is a specific inhibitors of Janus kinase 3 (JAK3).

4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE Suppliers

China 56 India 1 United Kingdom 2 United States 11 Global 70
VDM Biochemicals
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0330-2528181
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0330-2528171
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sales@vdmbio.com
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United States
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Target molecule Corp.
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857-239-0968
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857-239-8801
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service1@targetmol.com
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TargetMol Chemicals Inc.
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marketing@targetmol.com
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InvivoChem
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Aladdin Scientific
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+1-+1(833)-552-7181
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sales@aladdinsci.com
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Cayman Chemical Company
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cayman@caymanchem.com
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MedChemExpress
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Combi-Blocks Inc.
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Ryan Scientific, Inc.
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EMD Biosciences, Inc.
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21561-09-1, 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINERelated Search:

4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL WEHI-345 JAK3 INHIBITOR I 4-AMINO-3-CYANO-1,2,5,6-TETRAHYDROPYRIDINE WH-4-023 7-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE WHI-P97 JAK3 Inhibitor Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-

  • WHI-P258
  • JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258
  • 4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-
  • N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE
  • 6,7-dimethoxy-N-phenylquinazolin-4-amine
  • JAK3 INHIBITOR, NEGATIVE CONTROL
  • 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
  • 6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE
  • WHI P258,WHI-P258,inhibit,Inhibitor,JNK,WHI-P-258,WHIP258
  • 21561-09-1
  • Inhibitors