X-PHOS

Reaction

Product Name: X-PHOS
CAS No.: 564483-18-7
Chemical Name: X-PHOS
Synonyms: 5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE;2-Dicyclohexylphosphino-2;dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphane;X-PH0S;dicyclohexyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane;X-PHOS;98% XPhos;2-(DicycL;XPhos 97%;XPhos, >=98%
CBNumber: CB3357527
Molecular Formula: C33H49P
Formula Weight: 476.72
MOL File: 564483-18-7.mol

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X-PHOS Property

Melting point:: 187-190 °C(lit.)
Boiling point:: 569.8±50.0 °C(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: Benzene (Slightly)
form: Powder
color: white
Sensitive: Air Sensitive
Stability:: Air Sensitive
InChIKey: UGOMMVLRQDMAQQ-UHFFFAOYSA-N
CAS DataBase Reference: 564483-18-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-22-40
Safety Statements: 37/39-26-36/37
WGK Germany: 3
TSCA: No
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H351Suspected of causing cancer
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 638064
Product name: XPhos
Purity: 97%
Packaging: 1g
Price: $92.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 638064
Product name: XPhos
Purity: 97%
Packaging: 5g
Price: $171
Updated: 2024/03/01

TCI Chemical

Product number: D5038
Product name: 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl
Purity: >98.0%(GC)
Packaging: 1g
Price: $98
Updated: 2024/03/01

TCI Chemical

Product number: D5038
Product name: 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl
Purity: >98.0%(GC)
Packaging: 5g
Price: $288
Updated: 2024/03/01

Strem Chemicals

Product number: 15-1149
Product name: 2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% XPhos
Packaging: 500mg
Price: $33
Updated: 2024/03/01

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X-PHOS Chemical Properties,Usage,Production

Reaction

Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates.
Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling reaction and carbonyl enolate coupling.
Ligand used for the chemoselective amination of aryl chlorides.
Ligand used for the Pd-catalyzed borylation of aryl chlorides, for the formation of trifluoroborates.
Ligand used for the Pd-catalyzed amination of vinyl halides and triflates.
Ligand used for the Pd-catalyzed three-component synthesis of indoles.
Ligand used for the Pt-catalyzed regioselective hydrosilylation of functionalized terminal arylalkynes.
Ligand used for the Pd-catalyzed synthesis of carbazoles.
Ligand used for the Pd-catalyzed Suzuki-Miyaura coupling of aryl chloride and NHC-boranes.
Ligand used for the direct arylation of picoline N-oxide.
Ligand used for the Negishi coupling of 2-heterocyclic organozinc reagents.
Catalyst for a phosphine-catalyzed Heine reaction.
Ligand used for the palladium-catalyzed oxidative coupling of indoles and heteroarenes.
Ligand used for the silver-catalyzed hydrogenation of aldehydes.
Ligand used for the palladium-catalyzed cyanation of heterycyclic halides.

Chemical Properties

White crystalline powder

Uses

suzuki reaction

Uses

Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates. XPHOS is used as a regent in the synthesis of novel [1,2,4]triazolo[4,3-a]pyrazine derivatives as potential selective c-met inhibitors with improved pharmacokinetic properties.

General Description

This product has been enhanced for catalytic efficiency.

X-PHOS Preparation Products And Raw materials

Raw materials

2-Bromochlorobenzene Dicyclohexylchlorophosphine Carbon tetrachloride Hydroquinone Tetrahydrofuran 1,3,5-Triisopropylbenzene Ethyl acetate Copper(I) chloride Government regulation Dichloromethane Methanol Iron Magnesium

Preparation Products

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X-PHOS Suppliers

Americas 1 Belgium 3 Canada 1 China 378 Europe 1 France 3 Germany 9 India 15 Ireland 1 Italy 1 Japan 2 Norway 1 Russia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 10 United States 41 Global 473

Xinxiang Runyu Material Co., Ltd.

Tel: 166-166-37336996 15690792173
Fax: 0373-7759608
Email: chenxi.song@runvmat.com
Country: China
ProdList: 454
Advantage: 55

Nanjin Cynthia chemicals Technology Co.,Ltd

Tel: 0550-5618439 15951861180
Fax: 0550-5610690
Email: cynthiachem@163.com
Country: China
ProdList: 335
Advantage: 62

Sinocompound Catalysts Co., Ltd.

Tel: 0512-67216630 18962121273;
Fax: 0512-56316689
Email: sales@sinocompound.com
Country: China
ProdList: 273
Advantage: 64

Puyang Huicheng Electronic Material Co. Ltd.

Tel: 0393-0393-8910800 18339358320
Fax: 0393-8912775
Email: info@huichengchem.com
Country: China
ProdList: 550
Advantage: 64

Zhengzhou HQ Material Co., Ltd.

Tel: 0371-67759225 13526468238
Fax: +86-37155919558
Email: sales@hqmat.com
Country: China
ProdList: 525
Advantage: 60

Shanghai Chino Pharmaceutical Technology Co., Ltd

Tel: 021-021-51557188 15901710861
Fax: QQ: 569058060
Email: sales@channelpharm.com
Country: China
ProdList: 997
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19918
Advantage: 55

Creasyn Finechem(Tianjin) Co., Ltd.

Tel: 022-022-83946278 13820372920
Fax: 022-83945176
Email: sales@creasyn.com
Country: China
ProdList: 994
Advantage: 68

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169097
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

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View Lastest Price from X-PHOS manufacturers

Shanghai Affida new material science and technology center

Product: X-PHOS 564483-18-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 50000KG/month
Release date: 2024-03-13

Shanghai UCHEM Inc.

Product: 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl 564483-18-7
Price: US $26.00-461.00/g
Min. Order: 25g
Purity: 0.99
Supply Ability: 100kg
Release date: 2023-10-25

Hebei Mojin Biotechnology Co., Ltd

Product: X-PHOS 564483-18-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-23

564483-18-7, X-PHOSRelated Search:

5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE DIPOTASSIUM SALT 2-(Dicyclohexylphosphino)biphenyl DI-N-PENTYLPHENYLPHOSPHINE DIBUTYLPHENYLPHOSPHINE 2-(Dicyclohexylphosphino)-2'-methylbiphenyl X-PHOS Dicyclohexylphenylphosphine 5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE DISODIUM SALT PNP-PHOS K PNP-PHOS 2 CHX PNP-PHOS DINA HEXAHYDRATE 5-Bromo-4-chloro-3-indolyl phosphate hydrate disodium salt PHOS-ALPHA-D-GLC 2H2O 5-Bromo-4-chloro-3-indolyl phosphate p-toluidine salt PNP-PHOS DINA CYCLOHEXYLPHOSPHINE DICYCLOHEXYLPHOSPHINE GOAT F(AB')2 ANTI-HUMAN LAMBDA (F+B) ALK PHOS

X-PHOS

5-BROMO-4-CHLORO-3-INDOLYL PHOSPHATE

2-(DICYCLOHEXYLPHOSPHINO)-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL

2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL

2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISOPROPYLBIPHENYL

2-Dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl, X-PHOS

2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl,min.98%X-Phos

-biphenyl]-2-yl]phosphane

(2-(2,4,6-triisopropylphenethyl)phenyl)dicyclohexylphosphine(X-Phos)

X-PH0S

2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl, 98+%

ChemDose(R), X-Phos impregnated tablets, 2-Dicyclohexylphosphino-2μ,4μ,6μ-triisopropylbiphenyl impregnated tablets

X-Phos, ChemDose(R) tablets

2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbip

2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,

2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl ,97%

2-Dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl,XPhos

2-Dicyclohexylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl, 98+% X-PHOS

98% XPhos

2-(DicyclohexylphosphiNA)-2',4',6'-triisopropylbiphenyl

Dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphine

2,,4',6'-Diisopropyl-1,1'-biphenyl-2-yldicyclohexylphosphine

2-(Dicyclohexylphosphino)-2',4

2-(Dicyclohexylphosphanyl)-2',4',6'-tris(isopropyl)biphenyl

Dicyclohexyl[2',4',6'-tris(prop-2-yl)biphenyl-2-yl]phosphine, Dicyclohexyl[2',4',6'-tris(prop-2-yl)biphenyl-2-yl]phosphane, X-phos

2-(DicycL

phosphino)-2',4',6'-tri-i-propyL

Dicyclohexyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine

Phosphine, dicyclohexyl[2',4',6'-tris(1-Methylethyl)[1,1'-biphenyl]-2-yl]-

XPhos 97%

2-Dicyclohexylphosphino-2

2-(DICYCLOHEXYLPHOSPHINO)-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL OR X-PHOS

(2-(2,4,6-triisopropylphenethyl)phenyl)dicyclohexylphosphine

X-PHOS,2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl

XPhos, >=98%

Dicyclohexyl[2-(2,4,6-triisopropylphenyl)phenyl]phosphane

X-Phos, ChemDose? tablets

2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98%

dicyclohexyl(2',4',6'-triisopropyl-[1,1'-biphenyl]-2-yl)phosphane

dicyclohexyl[2',4',6'-tris(propan-2-yl)-[1,1'-biphenyl]-2-yl]phosphane

2-Dicyclohexylphosphino-2',4',6'-t

dicyclohexyl-[2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane

[2'-(methylamino)-[1,1'-biphenyl]-2-yl]palladio methanesulfonate

X-Phos, ChemDose(TM) tablets

-1,1'-biphenyL

2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl,min.98%

X-Phos ( 2-dicyclohexylphosphino-2’,4’,6’-triisopropylbiphenyl)

2-Dicyclohexylphosphino-2',4',6'-trisopropyl-1,1'-biphenyl(X-phos)

2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL,xphos

X-Phos (2-Dicyclohexylphosphino-2,4,6-Triisopropylbiphenyl) extrapure, 98%

2-Dicyclohexylphosphate-2 ', 4', 6 '- triisopropylbiphenyl

2-dicyclohexylphosphine 2',4',6' -triisopropyl biphenyl

Abemaciclib Impurity 31

Abemaciclib Impurity 39

2-(Dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1'-biphenyl

2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISO-PROPYL-1,1'-BIPHENYL

XPhos(2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl)

2,,4',6'-Diisopropyl-1,1'-biphenyl-2-yldicyclohexylphosphine