TBTU

Product Name: TBTU
CAS No.: 125700-67-6
Chemical Name: TBTU
Synonyms: TBTU;2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE;TBPIPU;TBTU N;TBTU, 98%;TBTU 99.5%;KNORR REAGENT;TBTU extrapure;TBTU [ 125700-67-6;TBTU (Knorr reagent)
CBNumber: CB3357547
Molecular Formula: C11H16BF4N5O
Formula Weight: 321.09
MOL File: 125700-67-6.mol

More

Less

TBTU Property

Melting point:: 205 °C (dec.)(lit.)
storage temp.: 2-8°C
solubility: acetonitrile: 0.1 g/mL, clear
form: Powder
color: White to Almost white
Water Solubility: Soluble in acetonitrile (100 mg/ml, clear, colorless), DMF (160.55 mg/ml, clear), and water (3 mg/ml at 20°C).
Sensitive: Moisture Sensitive
BRN: 7066325
InChI: InChI=1S/C11H16N5O.BF4/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
InChIKey: NQGZJNPFMLJDKU-UHFFFAOYSA-M
SMILES: [B+3]([F-])([F-])([F-])[F-].C(=[N+]1/N=N(=O)C2=CC=CC=C/12)(\N(C)C)/N(C)C
LogP: -2.65 at 21℃
CAS DataBase Reference: 125700-67-6(CAS DataBase Reference)
EPA Substance Registry System: 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1) (125700-67-6)

More

Less

Safety

Hazard Codes: Xi,F,E
Risk Statements: 36/37/38-5-2
Safety Statements: 26-36-37/39-36/37/39-35
RIDADR: 1325
WGK Germany: 3
F: 8-10-21
Hazard Note: Irritant/Flammable
HS Code: 2933 99 80
HazardClass: 4.1
PackingGroup: Ⅱ

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.51008
Product name: TBTU
Purity: 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate Novabiochem®
Packaging: 25 g
Price: $64.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.51008
Product name: TBTU
Purity: 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate Novabiochem®
Packaging: 100 g
Price: $198
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.51008
Product name: TBTU
Purity: 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate Novabiochem®
Packaging: 1 kg
Price: $444
Updated: 2025/07/31

Sigma-Aldrich

Product number: 12806
Product name: O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
Purity: ≥97.0% (N)
Packaging: 5G
Price: $70.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 12806
Product name: O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
Purity: ≥97.0% (N)
Packaging: 25g
Price: $193
Updated: 2025/07/31

More

Less

TBTU Chemical Properties,Usage,Production

Chemical Properties

TBTU [chemical name:2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate] is WHITE TO PALE CREAM FINE CRYSTALLINE POWDER

Uses

TBTU is a coupling reagent for peptide synthesis causing low racemization, which is ideally suited for solid-phase peptide synthesis. Also used in the synthesis of acid based t-antigen glycodendrimers.

reaction suitability

reaction type: Coupling Reactions

TBTU Preparation Products And Raw materials

Raw materials

Preparation Products

1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE

More

Less

TBTU Suppliers

Americas 1 Canada 3 China 442 Czech Republic 1 Europe 6 France 4 Germany 11 India 34 Israel 3 Japan 7 Poland 1 Slovakia 1 South Korea 1 Switzerland 7 The Netherlands 1 United Kingdom 21 United States 59 Global 603

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-69209928 18796809688
Fax: 0512-68417696
Email: zhouyingxiang@highfine.com
Country: China
ProdList: 475
Advantage: 75

Changzhow Moisten International Trading Co., Ltd.

Tel: 13606112397
Email: tang13606112397@163.com
Country: China
ProdList: 191
Advantage: 58

Shanghai Zhuorui Chemical Co.,Ltd.

Tel: 021-69180038
Fax: 0086-21-39177059
Email: zhuoruichem@163.com
Country: China
ProdList: 105
Advantage: 58

Lianyungang Guanxin Pharmaceutical Technology Co., Ltd

Tel: 15351860687
Email: 1462699602@qq.com
Country: China
ProdList: 42
Advantage: 58

Jiangsu Jitai Peptide Technology Co., Ltd.

Tel: 0515-8085-5066 13770132022
Email: sales05@gtaipeptide.com
Country: China
ProdList: 2675
Advantage: 58

Binhai gill polypeptide co. LTD

Tel: 021-61263389 13524856427
Fax: WeChat630417570
Email: Joetang@glschina.com
Country: China
ProdList: 10000
Advantage: 58

Shaoxing Jiufu New Material Technology Co., LTD

Tel: 0575-87095566 18067860628
Email: sales@sxjiufu.com
Country: China
ProdList: 410
Advantage: 58

Gill polypeptide biopharmaceutical (dalian) co., LTD

Tel: 021-61263455 13167021076
Email: amy@glschina.com
Country: China
ProdList: 9736
Advantage: 58

Sanjing New Materials Technology (Taizhou) Co., Ltd.

Tel: 15250805028
Fax: QQ：1048979734
Email: 1048979734@qq.com
Country: China
ProdList: 339
Advantage: 58

Jinan Daen Pharma Tech Co., Ltd.

Tel: 0531-15905416-458 15905416458
Email: 2479528971@qq.com
Country: China
ProdList: 309
Advantage: 58

More

Less

View Lastest Price from TBTU manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: TBTU 125700-67-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98
Supply Ability: 10000KGS
Release date: 2025-12-02

Xinxiang Juyuan Biological Technology Co., Ltd.

Product: TBTU 125700-67-6
Price: US $700.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 50TONS
Release date: 2025-08-05

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate 125700-67-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-10

125700-67-6, TBTURelated Search:

Tolyltriazole AZURE B TETRAFLUOROBORATE 1,1,3,3-Tetramethylurea 1H-Benzotriazole 5-Methyl-1H-benzotriazole Ribavirin 1,2,3-1H-Triazole O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one 2-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate HOAt 1-Hydroxybenzotriazole HBTU HATU Fluoroboric acid TBTU 1-Hydroxybenzotriazole hydrate

benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate

[benzotriazol-1-yloxy(dimethylamino)methylene]-dimethyl-ammonium

1-[Bis(dimethylamino)methylene]-1H-benzotriazolium 3-Oxide Tetrafluoroborate

O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE

O-(1H-BENZOTRIAZOLE-1-YL) N,N,N',N'-TETRAMETHYL URONIUM TETRAFLUOROBORATE

O-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYL-URONIUM TETRAFLUOROBORATE

O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-PENTAMETHYLENE-URONIUM TETRAFLUOROBORATE

O-(1H-BENZO-1,2,3-TRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYL-URONIUM TETRAFLUOROBORATE

O-(BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE

N-[(1H-BENZOTRIAZOL-1-YL)(DIMETHYL-AMINO)METHYLENE]-N-METHYL-METHANAMINIUM TETRAFLUOROBORATE

TBPIPU

TBTU

TETRAFLUOROBORATE TBTU

O-BENZOTRIAZOL-1-YL-N,N,N',N'-TETRA- &

O-BENZOTRIAZOL-1-YL-N,N,N',N'-TETRAMETHY LURONIUM

TBTU,O-(BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE

O-Benzotriazol-lYL-N,N',N'-Tetramethyluronium Tetrafluoroborate

2-(1H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE (TBTU)

O-Benzotriazol-1-yl-N,N,N',N'-tetramethylisouronium tetrafluoroborate

TBTU/2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumtetrafluoroborate

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluro

2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetraMethyluroni

1H-BenzotriazoliuM-1-[bis(diMethylaMine)

2-(1H-Benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetraMethyluroniuM tetrafluoroborate

TBTU, [(1H-Benzotriazol-1-yl)oxy](dimethylamino)-N,N-dimethylmethaniminium tetrafluoroborate

O-(BENZOTRIAZOLE-1-YL)-N,N,N',N'-TETRAMETHYL URONIUM TETRAFLUORO BORATE

KNORR REAGENT

2-(1H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE

2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE

O-(Benzotriazol-1-yl)-N,N,N',N'-tetraMethyluroniuM tetrafluoroborate >=97.0% (N)

3-[(dimethylamino)(dimethyliminiumyl)methyl]-1-oxo-2,3-dihydro-1H-1λ?,2,3-benzotriazol-1-ylium-2-ide

2-(1H-Benzotriazole-1-yl)-1,1,3,3-Tetram

TBTU (Knorr reagent)

O-(1H-BENZOTRIAZOL-1-YL)-N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE(TBTU)

O-Benzotriazol-l-yl- N,N,N'',N'',- tetramethyluroniumtetrafluoroborate

O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium Tetrafluoroborate (TBTU)

TDBTU (O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL)-N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE)

N-[(1H-Benzotriazol-1-yl)(dimethylamino)methylene]-N-methylmethanaminium tetrafluoroborate N-oxide

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate [Coupling Reagent for Peptide]

TBTU extrapure

benzotriazolyl tetramethyluronium fluoroborate

2-(1H-Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate, 97+%

TBTU (o-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium tetrafluo

benzotriazol-1-yl-N-tetramethyl-uronium tetrafluoroborate

O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium tetrafluoroborate,97%

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetraMethyluroniuM tetrafluoroborate, 99%, 99%

TBTU 99.5%

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate≥ 98% (HPLC)

N,N,N′,N′-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate

TBTU 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate Novabiochem

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate for synthesis

(Benzotriazol-1-yloxy-dimethylamino-methylene)dimethylammonium tetrafluoroborate

[dimethylamino-(3-oxidobenzotriazol-3-ium-1-yl)methylidene]-dimethylazanium

TBTU [Coupling Reagent for Peptide]

O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM TETRAFL

TBTU, N,N,Nμ,Nμ-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate [Coupling Reagent for Peptide]&gt

TBTU N