1-BOC-2-METHYL-PIPERIDIN-4-ONE
- Product Name
- 1-BOC-2-METHYL-PIPERIDIN-4-ONE
- CAS No.
- 190906-92-4
- Chemical Name
- 1-BOC-2-METHYL-PIPERIDIN-4-ONE
- Synonyms
- TERT-BUTYL 2-METHYL-4-OXOPIPERIDINE-1-CARBOXYLATE;N-Boc-2-methyl-piperidone;1-Boc-2-Methyl-Piperidinone;1-Boc-2-methyl-4-piperidi...;1-Boc-2-methyl-4-piperidinone;1-BOC-2-METHYL-PIPERIDIN-4-ONE;2-Methyl-4-oxo-piperidine-1-Boc;1-N-BOC-2-METHYL-PIPERIDIN-4-ONE;N-Boc-(+/-)-2-methyl-4-piperidone;2-Methyl-4-oxo-piperidine-1-Boc 97%
- CBNumber
- CB3358791
- Molecular Formula
- C11H19NO3
- Formula Weight
- 213.27
- MOL File
- 190906-92-4.mol
1-BOC-2-METHYL-PIPERIDIN-4-ONE Property
- Boiling point:
- 298.8±33.0 °C(Predicted)
- Density
- 1.060±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -1.52±0.40(Predicted)
- form
- solid
- color
- White to light yellow
- InChI
- InChI=1S/C11H19NO3/c1-8-7-9(13)5-6-12(8)10(14)15-11(2,3)4/h8H,5-7H2,1-4H3
- InChIKey
- HQMYWQCBINPHBB-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCC(=O)CC1C
- CAS DataBase Reference
- 190906-92-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- Hazard Note
- Irritant
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H310Fatal in contact with skin
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P263Avoid contact during pregnancy/while nursing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B423308
- Product name
- tert-Butyl2-Methyl-4-oxopiperidine-1-carboxylate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB140300
- Product name
- tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- S954
- Product name
- 1-Boc-2-methyl-4-piperidinone
- Packaging
- 250mg
- Price
- $78
- Updated
- 2021/12/16
- Product number
- FB140300
- Product name
- tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate
- Packaging
- 500mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- OR9058
- Product name
- 2-Methylpiperidin-4-one,N-BOCprotected
- Purity
- 97%
- Packaging
- 5g
- Price
- $95
- Updated
- 2021/12/16
1-BOC-2-METHYL-PIPERIDIN-4-ONE Chemical Properties,Usage,Production
Uses
1-Boc-2-methyl-piperidin-4-one s a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.
Synthesis
126503-08-0
190906-92-4
1-tert-butoxycarbonyl-2-methyl-4-piperidone vinyl acetal (6.00 g) was used as starting material and dissolved in acetone (150 mL). To this solution, p-toluenesulfonic acid monohydrate (4.40 g) was slowly added under ice bath cooling and stirring conditions. After addition, the reaction mixture was gradually warmed to room temperature with continuous stirring overnight. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate and the organic layer was subsequently washed with saturated sodium bicarbonate solution and saturated aqueous sodium chloride solution sequentially. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent to afford 1-tert-butoxycarbonyl-2-methyl-piperidone (2.40 g, 48% yield) as a yellow oil. Its 1H NMR (500 MHz, CDCl3) data were as follows: δ 1.18 (3H, d, J=7.0 Hz), 1.49 (9H, s), 2.20-2.30 (1H, m), 2.30-2.40 (1H, m), 2.45-2.55 (1H, m), 2.65-2.70 (1H, m), 3.25-3.35 ( 1H, m), 3.90-4.05 (1H, m), 4.20-4.30 (1H, m).
References
[1] Patent: EP1375482, 2004, A1. Location in patent: Page 153
1-BOC-2-METHYL-PIPERIDIN-4-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
1-BOC-2-METHYL-PIPERIDIN-4-ONE Suppliers
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- United Kingdom
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View Lastest Price from 1-BOC-2-METHYL-PIPERIDIN-4-ONE manufacturers
- Product
- 1-BOC-2-METHYL-PIPERIDIN-4-ONE 190906-92-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 1-BOC-2-METHYL-PIPERIDIN-4-ONE 190906-92-4
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-08-05