Bis(2-dimethylaminoethyl) ether Property

Boiling point:

189 °C/760 mmHg

Density 

0.841 g/mL at 25 °C

vapor pressure 

49Pa at 20℃

refractive index 

n 20/D 1.430

Flash point:

151 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Soluble in water

form 

clear liquid

pka

9.12±0.28(Predicted)

color 

Colorless to Light yellow

Water Solubility 

100g/L at 20℃

BRN 

1739668

Exposure limits

ACGIH: TWA 0.05 ppm; STEL 0.15 ppm (Skin)

InChIKey

GTEXIOINCJRBIO-UHFFFAOYSA-N

LogP

-0.34 at 20℃

CAS DataBase Reference

3033-62-3(CAS DataBase Reference)

NIST Chemistry Reference

Ethanamine, 2,2'-oxybis[N,N-dimethyl-(3033-62-3)

EPA Substance Registry System

Bis[2-(dimethylamino)ethyl]ether (3033-62-3)

Safety

Hazard Codes 

T

Risk Statements 

20-22-24-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2927 6.1/PG 2

WGK Germany 

2

RTECS 

KR9460000

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29221990

Hazardous Substances Data

3033-62-3(Hazardous Substances Data)

Toxicity

LD50 orl-rat: 1070 mg/kg JTOTDO 5,3,86

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Bis(2-dimethylaminoethyl) ether Chemical Properties,Usage,Production

Chemical Properties

Colorless and transparent liquid or Brown liquid. Soluble in water, easily soluble in alcohol, benzene, etc.

Uses

Bis(2-dimethylaminoethyl) ether is an efficient tertiary amine catalyst, which is suitable for the production of almost all foam products, mainly for the production of flexible foam products, especially for high resilience and RIM products. It is characterized by high catalytic activity, smooth foaming, large tolerance to tin, easy to adjust the formulation, and the physical and chemical properties of products produced with it, such as resilience and elongation, are better than other products.

Preparation

The main methods for the synthesis of Bis(2-dimethylaminoethyl) ether are:
(1) reaction of sodium dimethylaminoethanol and SO3 or chlorosulfonic acid;
(2) Reaction of trimethylamine with dichloroethyl ether or dimethylaminoethoxyethyl ether;
(3) One-step synthesis of dimethylamine and monoethyleneglycol under solid catalyst.

Application

Bis(2-dimethylaminoethyl) Ether (Potassium Clavulanate EP Impurity M) is used in the manufacturing of flexible polyurethane foams.

General Description

Bis(2-(dimethylamino)ethyl)ether appears as a clear or yellow liquid. Bp: 188°C. Toxic by inhalation, by skin absorption, ingestion, and eye contact.

Reactivity Profile

Bis (2-(dimethylamino)ethyl)ether reacts as a base. Reacts exothermically with acids. May form explosive peroxides upon exposure to the air.

Safety Profile

Poison by skin contact.Moderately toxic by ingestion. Experimental reproductiveeffects. A severe skin and eye irritant.