4-Bromo-2-fluorobenzaldehyde

Product Name: 4-Bromo-2-fluorobenzaldehyde
CAS No.: 57848-46-1
Chemical Name: 4-Bromo-2-fluorobenzaldehyde
Synonyms: 2-FLUORO-4-B;4-Bromo-2-fluoro benzelhyde;4-BROMO-2-FLUOROBENZALDEHYDE;2-FLUORO-4-BROMOBENZALEDHYDE;2-FLUORO-4-BROMOBENZALDEHYDE;Benzaldehyde, 4-bromo-2-fluoro-;4-Bromo-2-fluorobenzaldehyde98%;4-Bromo-2-fluorobenzaldehyde,96%;4-Bromo-2-fluorobenzaldehyde 98%;4-Bromo-2-fluorobenzaldehyde >
CBNumber: CB3377073
Molecular Formula: C7H4BrFO
Formula Weight: 203.01
MOL File: 57848-46-1.mol

More

Less

4-Bromo-2-fluorobenzaldehyde Property

Melting point:: 58-62 °C (lit.)
Boiling point:: 42°C 19mm
Density: 1.6698 (rough estimate)
refractive index: 1.5700 (estimate)
Flash point:: 42°C/19mm
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
color: White to Orange to Green
Water Solubility: INSOLUBLE
Sensitive: Air Sensitive
BRN: 7700208
InChI: InChI=1S/C7H4BrFO/c8-6-2-1-5(4-10)7(9)3-6/h1-4H
InChIKey: UPCARQPLANFGQJ-UHFFFAOYSA-N
SMILES: C(=O)C1=CC=C(Br)C=C1F
CAS DataBase Reference: 57848-46-1(CAS DataBase Reference)
NIST Chemistry Reference: 2-Fluoro-4-bromobenzaldehyde(57848-46-1)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26-36
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT, AIR SENSITIVE
HS Code: 29130000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 465232
Product name: 4-Bromo-2-fluorobenzaldehyde
Purity: 96%
Packaging: 5g
Price: $25
Updated: 2023/06/20

Sigma-Aldrich

Product number: 465232
Product name: 4-Bromo-2-fluorobenzaldehyde
Purity: 96%
Packaging: 25g
Price: $119
Updated: 2023/06/20

TCI Chemical

Product number: B2002
Product name: 4-Bromo-2-fluorobenzaldehyde
Purity: >96.0%(GC)
Packaging: 5g
Price: $61
Updated: 2025/07/31

TCI Chemical

Product number: B2002
Product name: 4-Bromo-2-fluorobenzaldehyde
Purity: >96.0%(GC)
Packaging: 25g
Price: $174
Updated: 2025/07/31

TRC

Product number: B684520
Product name: 4-Bromo-2-fluorobenzaldehyde
Packaging: 10g
Price: $130
Updated: 2021/12/16

More

Less

4-Bromo-2-fluorobenzaldehyde Chemical Properties,Usage,Production

Chemical Properties

lightyellowtobeigecrystal

Uses

4-Bromo-2-fluorobenzaldehyde is used in the preparation of nigeglanine hydrobromide.

Uses

4-Bromo-2-fluorobenzaldehyde has been used in the preparation of:

2-functionalized aromatic monoaldehydes, via reaction with different secondary amines and phenol
fluorostilbenes
benzyl amine-based histamine H3 antagonist having serotonin reuptake activity
6-bromo-2-(4-bromo-2-fluorophenyl)-2,3-dihydro-4H-chromen-4-one

Uses

4-Bromo-2-fluorobenzaldehyde is used in the synthesis of Nigeglanine hydrobromide.

Synthesis

222978-01-0

57848-46-1

General procedure for the synthesis of 4-bromo-2-fluorobenzaldehyde from 4-bromo-3-fluorobenzyl alcohol: To a solution of 4-bromo-3-fluorobenzyl alcohol (7.9 g, 38.5 mmol) in dichloromethane (160.0 mL) was added sodium acetate (940 mg, 11.5 mmol) and pyridinium chlorochromate (10.8 g, 50.0 mmol) sequentially. The reaction mixture was stirred at room temperature and protected from light for 2 hours. After completion of the reaction, the mixture was diluted with ethyl acetate (1.0 L) and filtered through a diatomaceous earth pad. The filtrate was washed sequentially with aqueous sodium bicarbonate (600 mL) and water (600 mL) and subsequently dried with anhydrous sodium sulfate. After evaporation of the solvent under reduced pressure, the resulting crude product was further purified by column chromatography to afford 4-bromo-2-fluorobenzaldehyde as a white solid (5.0 g, 63% yield).

References

[1] Patent: WO2011/21209, 2011, A1. Location in patent: Page/Page column 38; 39
[2] Patent: US2012/101099, 2012, A1. Location in patent: Page/Page column 13; 14

4-Bromo-2-fluorobenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-Bromo-2-fluorobenzaldehyde Suppliers

Americas 1 Belgium 2 Canada 2 China 374 Europe 4 France 2 Germany 4 India 11 Italy 1 Japan 5 Jordan 1 Slovakia 1 Switzerland 3 Ukraine 2 United Kingdom 23 United States 55 Global 491

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

CHANGZHOU FLUORIDE CHEMICAL CO.,LTD

Tel: 0086-519-89892883 15995021858
Fax: 0519-85227531
Email: info@fluoridechem.com
Country: China
ProdList: 80
Advantage: 58

JIANGYIN RUISHIPHARM CO.,LIMITED

Tel: 0510-0510-66227179 18921203887
Fax: +86-0510-66227179 QQ:2200317867
Email: sales@ruishipharm.com
Country: China
ProdList: 749
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Liaoning Tianhua Chemical Co., Ltd.

Tel: 0418-6530555 2855550
Fax: +86-418-6502885
Country: China
ProdList: 338
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing dtftchem Technology Co., Ltd.

Tel: 010-60275820 13031183356
Fax: 010-60270825
Email: elainezt@sina.com
Country: China
ProdList: 1390
Advantage: 62

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

More

Less

View Lastest Price from 4-Bromo-2-fluorobenzaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Bromo-2-fluorobenzaldehyde 57848-46-1
Price: US $9.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-12-03

LY Global chemicals co.,ltd .

Product: 4-Bromo-2-fluorobenzaldehyde 57848-46-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%Min
Supply Ability: 1000kg
Release date: 2023-03-13

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Bromo-2-fluorobenzaldehyde 57848-46-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

57848-46-1, 4-Bromo-2-fluorobenzaldehydeRelated Search:

4'-Bromopropiophenone Transfluthrin 1,2-Difluorobenzene 2-Bromofluorobenzene Bromoxynil octanoate Florfenicol 4-Fluorobenzaldehyde 4-Bromobenzaldehyde 4-Bromo-2-fluorobenzoic acid 3-Bromofluorobenzene 3-Bromoanisole Bromoxynil 4-Bromofluorobenzene Bromine 4-Bromo-2,6-difluorobenzoic acid 4-BROMO-2,3,5,6-TETRAFLUOROBENZOYL CHLORIDE FENFLURAMINE 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID

4-Bromo-2-fluorobenzaldehyde 98%

4-Bromo-2-fluorobenzaldehyde98%

Benzaldehyde, 4-bromo-2-fluoro-

4-Bromo-2-fluorobenzaldehyde,96%

4-BroMo-2-fluorobenzaldehyde, 96% 5GR

4-BroMo-2-fluorobenzaldehyde, 97+%

2-FLUORO-4-BROMOBENZALDEHYDE

2-FLUORO-4-BROMOBENZALEDHYDE

4-BROMO-2-FLUOROBENZALDEHYDE

4-Bromo-2-Fluorobenzaldehyde 2-Fluoro-4-Bromobenzaldehyde

2-FLUORO-4-B

4-Bromo-2-fluorobenzaldehyde &gt

4-Bromo-2-fluorobenzaldehyde ISO 9001：2015 REACH

4-Bromo-2-fluoro benzelhyde

(2-Bromo-5-methoxy-29-methyl-phenyl)-methano

57848-46-1

BrC6H3FCHO

ALDEHYDE

Organic Building Blocks

Aldehydes

Building Blocks

C7

Carbonyl Compounds

Benzaldehyde (Building Blocks for Liquid Crystals)

Building Blocks for Liquid Crystals

FINE Chemical & INTERMEDIATES

Aromatic Aldehydes & Derivatives (substituted)

Fluorobenzene

Fluorin-contained benzaldehyde series

Aldehydes

C7

Carbonyl Compounds

Benzene series

Benzaldehyde

Miscellaneous

Adehydes, Acetals & Ketones

Bromine Compounds

Fluorine Compounds

Benzaldehyde (Building Blocks for Liquid Crystals)

Building Blocks for Liquid Crystals

Functional Materials

bc0001