ChemicalBook > CAS DataBase List > DL-O-METHYLSERINE
DL-O-METHYLSERINE
- Product Name
- DL-O-METHYLSERINE
- CAS No.
- 19794-53-7
- Chemical Name
- DL-O-METHYLSERINE
- Synonyms
- Methylserine;DL-Ser(Me)-OH;DL-H-Ser(Me)-OH;O-Methyl-DL-serin;DL-O-METHYLSERINE;O-METHYL-DL-SERINE;DL-O-Methylserine>DL-O-Methylserine,>98%,;2-Amino-3-methoxy-propionic acid;DL-O-Methylserine
- CBNumber
- CB3393228
- Molecular Formula
- C4H9NO3
- Formula Weight
- 119.12
- MOL File
- 19794-53-7.mol
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DL-O-METHYLSERINE Property
- Boiling point:
- 260.6±30.0 °C(Predicted)
- Density
- 1.195±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- powder to crystal
- pka
- 2.10±0.10(Predicted)
- color
- White to Almost white
- CAS DataBase Reference
- 19794-53-7(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2922500090
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- M7378
- Product name
- O-Methyl-DL-serine
- Packaging
- 1g
- Price
- $452
- Updated
- 2023/06/20
TCI Chemical
- Product number
- M0888
- Product name
- DL-O-Methylserine
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $161
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M0888
- Product name
- DL-O-Methylserine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $541
- Updated
- 2025/07/31
TRC
- Product number
- M327520
- Product name
- O-Methylserine
- Packaging
- 5g
- Price
- $435
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0001536
- Product name
- 2-AMINO-3-METHOXYPROPANOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $708.48
- Updated
- 2021/12/16
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DL-O-METHYLSERINE Chemical Properties,Usage,Production
Uses
O-Methylserine acts as a reagent for the synthesis of D-serine transporter inhibitors which are used pharmaceutically for the treatment of visual system disorders and enhancement of the visual functions.
Definition
ChEBI: O-Methyl-DL-serine is an alpha-amino acid.
Synthesis
27704-96-7
19794-53-7
1) Add 215 g of methyl acrylate to the reaction flask. The temperature of the reaction system was raised to 55°C and 500 g of bromine was added slowly and dropwise. The reaction was maintained for 1 hour. Subsequently, concentration was carried out under reduced pressure at 60 °C to remove the excess bromine. To the residue was added 1260 g of methanol and the mixture was cooled to -17 °C. At this temperature, 127 g of sodium methanol was added and the reaction was carried out for 5.5 hours. Upon completion of the reaction, the methanol was removed by distillation under reduced pressure. 750 g of ammonia was added to the reaction mixture and the reaction was held at 20-25°C for 3 hours. Finally, 260 g of O-methyl-DL-serine was obtained by concentrated crystallization.
References
[1] Patent: CN105949074, 2016, A. Location in patent: Paragraph 0041
DL-O-METHYLSERINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DL-O-METHYLSERINE manufacturers
Career Henan Chemical Co
- Product
- DL-O-METHYLSERINE 19794-53-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-12-19
19794-53-7, DL-O-METHYLSERINERelated Search:
2-HYDRAZINOCARBONYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
H-SER(TBU)-OTBU HCL
DL-O-METHYLSERINE
O-BENZYL-DL-SERINE
FMOC-O-tert-Butyl-L-serine
Diethyl nitromalonate
H-THR(TBU)-OH
O-ACETYL-L-SERINE
Diethyl aminomalonate hydrochloride
AZASERINE
DIETHYL BENZAMIDOMALONATE
Dimethyl nitromalonate
Z-SER(BZL)-OH
Diethyl acetamidomalonate
DIETHYL ACETAMIDOMALONATE-2-13C
DIETHYL FORMAMIDOMALONATE
DL-A-METHYLSERINE,DL-2-METHYLSERINE
DL-Serine