ChemicalBook > CAS DataBase List > FMOC-O-tert-Butyl-L-serine

FMOC-O-tert-Butyl-L-serine

Product Name
FMOC-O-tert-Butyl-L-serine
CAS No.
71989-33-8
Chemical Name
FMOC-O-tert-Butyl-L-serine
Synonyms
FMOC-SER(TBU)-OH;FMOC-SER(TBU);FMOC-L-SER(TBU)-OH;FMOC-SER(BUT);Fomc-Ser(tBu)-OH;FMOC-L-Ser(tBu)-OH 98%;Fomc-Ser(t;Fmoc-Ser(OBut);FMOC-L-SER(T-BU);FMOC-SER(BUT)-OH
CBNumber
CB4315210
Molecular Formula
C22H25NO5
Formula Weight
383.44
MOL File
71989-33-8.mol
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FMOC-O-tert-Butyl-L-serine Property

Melting point:
130.5-135.5 °C(lit.)
alpha 
25 º (c=1,EtOAc 24 ºC)
Boiling point:
510.36°C (rough estimate)
Density 
1.2369 (rough estimate)
refractive index 
24 ° (C=1, AcOEt)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.44±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
optical activity
[α]20/D +25.5±1°, c = 1% in ethyl acetate
BRN 
3632013
InChI
InChI=1S/C22H25NO5/c1-22(2,3)28-13-19(20(24)25)23-21(26)27-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChIKey
REITVGIIZHFVGU-IBGZPJMESA-N
SMILES
C(O)(=O)[C@H](COC(C)(C)C)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference
71989-33-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36/37/39-27-26
WGK Germany 
3
HS Code 
29242990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
25g
Price
$90.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
100g
Price
$326
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
250g
Price
$687
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52019
Product name
Fmoc-Ser(tBu)-OH
Purity
Novabiochem?
Packaging
1kg
Price
$2360
Updated
2024/03/01
Sigma-Aldrich
Product number
47619
Product name
Fmoc-Ser(tBu)-OH
Purity
≥98.0% (HPLC)
Packaging
10g
Price
$67.9
Updated
2024/03/01
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FMOC-O-tert-Butyl-L-serine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Ser(tBu)-OH is an N-terminal protected reagent used in the peptide synthesis. Some of the reported examples are:

  • Total synthesis of an antibiotic, daptomycin, by cyclization via a chemoselective serine ligation.
  • Preparation of MUC1, a T-cell helper peptide, using iterative pentafluorophenyl ester-mediated fragment condensations.
  • Linear solid-phase peptide synthesis of ubiquitin and diubiquitin.

General Description

The product number for this product was previously 04-12-1033.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

FMOC-O-tert-Butyl-L-serine Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-O-tert-Butyl-L-serine Suppliers

Lanxi Xingnuo Import and Export Trading Co., Ltd
Tel
15888978871 15888978871
Email
994350525@qq.com
Country
China
ProdList
23
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9960
Advantage
55
Chengdu Aminotp Pharmaceutical Technology Co.,Ltd.
Tel
028-85755578 18140172005
Fax
028-85755578
Email
sales@aminotp.com
Country
China
ProdList
309
Advantage
58
Chengdu Tachem Co., Ltd
Tel
19983060238
Email
sales@tachem.cn
Country
China
ProdList
109
Advantage
58
shanghai Yanfeng biochemical technology Co.,LTD
Tel
021-13611955358 13611955358
Email
yanfen2023@126.com
Country
China
ProdList
1139
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
Sichuan Tongsheng Amino acids Co.,Ltd.
Tel
0838-2809458 13350585791
Fax
+86-838-2274207
Email
pharm@biots.cn
Country
China
ProdList
349
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
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View Lastest Price from FMOC-O-tert-Butyl-L-serine manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Ser(tBu)-OH 71989-33-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-12-07
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Fmoc-Ser(tBu)-OH 71989-33-8
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-26
Chengdu Baishixing Science and Technology Industry Co.,Ltd
Product
Fmoc-Ser(tbu)-OH 71989-33-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2T/month
Release date
2023-07-21

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